Mode of Insertion of the Signal Sequence of a Bacterial Precursor Protein into Phospholipid Bilayers As Revealed by Cysteine-Based Site-Directed Spectroscopy

Principles of Fluorescence Spectroscopy

1983 • 5,123 citations

Signal sequences

1985 • 2,179 citations

Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells.

1984 • 230 citations

Characterization of membrane-associated and soluble states of SecA protein from wild-type and SecA51(TS) mutant strains of Escherichia coli.

1991 • 196 citations

Deep penetration of a portion of Escherichia coli SecA protein into model membranes is promoted by anionic phospholipids and by partial unfolding.

1992 • 183 citations

Negatively charged phospholipids restore prePhoE translocation across phosphatidylglycerol-depleted Escherichia coli inner membranes

1991 • 159 citations

SecA protein needs both acidic phospholipids and SecY/E protein for functional high-affinity binding to the Escherichia coli plasma membrane.

1991 • 150 citations

ProOmpA contains secondary and tertiary structure prior to translocation and is shielded from aggregation by association with SecB protein.

1990 • 114 citations

Induction of non-bilayer lipid structures by functional signal peptides.

1990 • 107 citations

Protein translocation: Common themes from bacteria to man

1994 • 74 citations

Characterization of the interfacial behavior and structure of the signal sequence of Escherichia coli outer membrane pore protein PhoE.

1988 • 72 citations

SecB Protein Stabilizes a Translocation-Competent State of Purified prePhoE Protein

1989 • 67 citations

OmpF-Lpp signal sequence mutants with varying charge hydrophobicity ratios provide evidence for a phosphatidylglycerol-signal sequence interaction during protein translocation across the Escherichia coli inner membrane

1993 • 61 citations

A dual role for phosphatidylglycerol in protein translocation across the Escherichia coli inner membrane.

1994 • 59 citations

Anionic phospholipids and protein translocation

1994 • 52 citations

Nucleotide and negatively charged lipid‐dependent vesicle aggregation caused by SecA

1993 • 33 citations

Protein translocation in Escherichia coli

1994 • 31 citations

Continuous-Wave Saturation of Two-Component, Inhomogeneously Broadened, Anisotropic EPR Spectra

1993 • 24 citations

Insertion mutagenesis on a cell-surface-exposed region of outer membrane protein PhoE of Escherichia coli K-12

1987 • 23 citations

Requirement for conformational flexibility in the signal sequence of precursor protein.

1994 • 23 citations

Phosphatidylglycerol dependent protein translocation across the Escherichia coli inner membrane is inhibited by the anti‐cancer drug doxorubicin

1993 • 22 citations

Biochemical characterization of the presecretory protein translocation machinery of Escherichia coli

1994 • 22 citations