Schnurri interacts with Mad in a Dpp‐dependent manner

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The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

Transcriptional Activators of TGF-β Responses: Smads

1998 • 1,024 citations

Synergistic Signaling in Fetal Brain by STAT3-Smad1 Complex Bridged by p300

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Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription

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A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

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A transcriptional partner for MAD proteins in TGF-β signalling

1996 • 699 citations

GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex.

1995 • 682 citations

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.

1995 • 672 citations

Signal transduction by bone morphogenetic proteins

1998 • 528 citations

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation

1998 • 527 citations

Smad2 and Smad3 Positively and Negatively Regulate TGFβ-Dependent Transcription through the Forkhead DNA-Binding Protein FAST2

1998 • 513 citations

TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300

1998 • 503 citations

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Physical and Functional Interaction of SMADs and p300/CBP

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Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

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TGF-β Family Signal Transduction in Drosophila Development: From Mad to Smads

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Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila

1994 • 317 citations

An absolute requirement for both the type II and type I receptors, punt and thick veins, for Dpp signaling in vivo

1995 • 312 citations

Synergistic cooperation of TFE3 and Smad proteins in TGF-β-induced transcription of the plasminogen activator inhibitor-1 gene

1998 • 288 citations

Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors

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Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family

1995 • 275 citations

Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic

1994 • 275 citations

Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing

1996 • 264 citations

Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

1994 • 254 citations

Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to theDrosophila mesoderm

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A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence.

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Characterization of Human FAST-1, a TGFβ and Activin Signal Transducer

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The drosophila schnurri gene acts in the Dpp/TGFβ signaling pathway and encodes a transcription factor homologous to the human MBP family

1995 • 212 citations

TGF-β–induced Phosphorylation of Smad3 Regulates Its Interaction with Coactivator p300/CREB-binding Protein

1998 • 211 citations

A kinase subdomain of transforming growth factor-β (TGF-β) type I receptor determines the TGF-β intracellular signaling specificity

1997 • 203 citations

schnurri is required for drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1

1995 • 200 citations

The Drosophila Activin receptor Baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development

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Characterization of a Bone Morphogenetic Protein-responsive Smad-binding Element

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CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor β transcriptional responses in endothelial cells

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A large protein containing zinc finger domains binds to related sequence elements in the enhancers of the class I major histocompatibility complex and kappa immunoglobulin genes.

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The decapentaplegic gene: a TGF-β homologue controlling pattern formation in Drosophila

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The Drosophila saxophone Gene: a Serine-Threonine Kinase Receptor of the TGF-β Superfamily

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A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling

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E1A Inhibits Transforming Growth Factor-β Signaling through Binding to Smad Proteins

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Spatially Restricted Activation of the SAX Receptor by SCW Modulates DPP/TKV Signaling in Drosophila Dorsal–Ventral Patterning

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Interplay of Signal Mediators of Decapentaplegic (Dpp): Molecular Characterization of Mothers against dpp, Medea, and Daughters against dpp

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A function of CBP as a transcriptional co-activator during Dpp signalling

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Putative Metal Finger Structure of the Human Immunodeficiency Virus Type 1 Enhancer Binding Protein HIV-EP1

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Angiotensinogen gene-inducible enhancer-binding protein 1, a member of a new family of large nuclear proteins that recognize nuclear factor kappa B-binding sites through a zinc finger motif.

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Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-β family signals

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Cell Fate Specification in theDrosophilaSalivary Gland: The Integration of Homeotic Gene Function with the DPP Signaling Cascade

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HIV-EP2, a new member of the gene family encoding the human immunodeficiency virus type 1 enhancer-binding protein. Comparison with HIV-EP1/PRDII-BF1/MBP-1

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Structure and expression of major histocompatibility complex-binding protein 2, a 275-kDa zinc finger protein that binds to an enhancer of major histocompatibility complex class I genes.

1992 • 51 citations

Drosophila dSmad2 and Atr‐I transmit activin/TGFβ signals

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Regulation of human immunodeficiency virus enhancer function by PRDII-BF1 and c-rel gene products

1992 • 39 citations

Isolation of two cDNAs encoding zinc finger proteins which bind to the α₁antitrypsin promoter and to the major histocompatibility complex class I enhancer

1991 • 33 citations

Identification of a NovelDrosophilaSMAD on the X Chromosome

1998 • 28 citations

Genetic and biochemical analysis of TGFβ signal transduction

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Cloning and characterization of a c-myc intron binding protein (MIBP1)

1994 • 25 citations