Selenium Supplementation Suppresses Tumor Necrosis Factor α-Induced Human Immunodeficiency Virus Type 1 Replicationin Vitro

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 • 1,524 citations

Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat.

1989 • 781 citations

SYSTEMIC GLUTATHIONE DEFICIENCY IN SYMPTOM-FREE HIV-SEROPOSITIVE INDIVIDUALS

1989 • 725 citations

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity.

1995 • 599 citations

Activation of HIV gene expression during monocyte differentiation by induction of NF-kB

1989 • 590 citations

Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

1993 • 581 citations

A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity.

1996 • 540 citations

Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.

1996 • 471 citations

Characterization of the AIDS-associated retrovirus reverse transcriptase and optimal conditions for its detection in virions

1985 • 449 citations

Glutathione deficiency and human immunodeficiency virus infection

1992 • 409 citations

Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway.

1994 • 389 citations

Cytokine-stimulated human immunodeficiency virus replication is inhibited by N-acetyl-L-cysteine.

1990 • 381 citations

Low Concentrations of Acid-Soluble Thiol (Cysteine) in the Blood Plasma of HIV-1-Infected Patients

1989 • 349 citations

Interferon-α But Not AZT Suppresses HIV Expression in Chronically Infected Cell Lines

1989 • 339 citations

Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine.

1991 • 330 citations

Characterization of a promonocyte clone chronically infected with HIV and inducible by 13-phorbol-12-myristate acetate.

1988 • 323 citations

Interferons and bacterial lipopolysaccharide protect macrophages from productive infection by human immunodeficiency virus in vitro.

1989 • 283 citations

Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression.

1996 • 283 citations

Inhibition of HIV-1 replication and NF-x B activity by cysteine and cysteine derivatives

1991 • 256 citations

Redox regulation of signal transduction: tyrosine phosphorylation and calcium influx.

1994 • 220 citations

Lipid hydroperoxides induce apoptosis in T cells displaying a HIV-associated glutathione peroxidase deficiency.

1994 • 205 citations

Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor-dependent cytotoxicity on U937 cells.

1991 • 201 citations

Stimulation of Glutathione Peroxidase Activity Decreases HIV Type 1 Activation after Oxidative Stress

1994 • 164 citations

Increased Virulence of a Human Enterovirus (Coxsackievirus B3) in SeleniumDeficient Mice

1994 • 162 citations

Intracellular Glutathione Levels in T Cell Subsets Decrease in HIV-Infected Individuals

1992 • 161 citations

Tumor Necrosis Factor- /Caehectin Enhances Human Immunodeficiency Virus Type 1 Replication in Primary Macrophages

1991 • 149 citations

Selenium deficiency in HIV infection and the acquired immunodeficiency syndrome (AIDS)

1994 • 146 citations

Tumour necrosis factors (α, β) induced by HIV-1 in peripheral blood mononuclear cells potentiate virus replication

1990 • 145 citations

A preliminary report on the intervention trials of primary liver cancer in high-risk populations with nutritional supplementation of selenium in China

1991 • 142 citations

Activation of Human Immunodeficiency Virus Type 1 by Oxidative Stress

1990 • 142 citations

Kinetics of cytokine expression during primary human immunodeficiency virus type 1 infection.

1996 • 136 citations

Antioxidants Inhibit Stimulation of HIV Transcription

1993 • 114 citations

Serum selenium concentration and disease progress in patients with HIV infection

1991 • 104 citations

Stimulation of a human T-cell clone with anti-CD3 or tumor necrosis factor induces NF-kappa B translocation but not human immunodeficiency virus 1 enhancer-dependent transcription.

1990 • 93 citations

Selenium-mediated inhibition of mouse mammary tumorigenesis

1980 • 89 citations

Glutathione and N-Acetylcysteine Suppression of Human Immunodeficiency Virus Replication in Human Monocyte/Macrophages In Vitro

1992 • 80 citations

Selenium Deficiency and Cardiomyopathy in Acquired Immunodeficiency Syndrome

1991 • 76 citations

Selenium in the maintenance and therapy of HIV-infected patients

1994 • 73 citations

Post-transcriptional regulation of glutathione peroxidase gene expression by selenium in the HL-60 human myeloid cell line

1989 • 71 citations

Role of lipid peroxidation in hematoporphyrin derivative-sensitized photokilling of tumor cells: protective effects of glutathione peroxidase.

1989 • 68 citations

Differential effect of monoclonal anti-DR antibody on monocytes in antigen- and mitogen-stimulated responses: Mechanism of inhibition and relationship to interleukin 1 secretion

1983 • 65 citations

Regulation of Human Immunodeficiency Virus Infection: Implications For Pathogenesis

1994 • 61 citations

A human T-cell line resistant to cytopathic effects of the human immunodeficiency virus (HIV)

1987 • 60 citations

Relationship of trace element, immunological markers, and HIV1 infection progression

1995 • 57 citations

Serum trace element levels in HIV-infected subjects

1990 • 44 citations

The Lipophilic Muramyl Peptide MTP-PE Is a Potent Inhibitor of HIV Replication in Macrophages

1990 • 42 citations

Molecular Biology of Selenium and Its Role in Human Health

1996 • 27 citations

Appraisal of Potential Therapeutic Index of Antioxidants on the Basis of TheirIn VitroEffects on HIV Replication in Monocytes and Interleukin 2-Induced Lymphocyte Proliferation

1994 • 25 citations

Sodium selenite inhibition of the reproduction of some oncogenic RNA-viruses

1981 • 20 citations

Cellular immune responses to HIV-1 in progressive and non-progressive infections

1996 • 15 citations

Is TNF involved in the progression of AIDS?

1990 • 7 citations