Peripheral tolerance in mice expressing a liver-specific class I molecule: inactivation/deletion of a T-cell subpopulation.

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

1989 • 1,010 citations

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

1988 • 505 citations

Acquisition of immunologic self-tolerance

1989 • 484 citations

Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

1988 • 476 citations

Clonal anergy induced in mature Vβ6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells

1989 • 462 citations

Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells

1988 • 343 citations

Induction of classical transplantation tolerance in the adult.

1989 • 325 citations

Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic β cells

1988 • 266 citations

Tolerance of class I histocompatibility antigens expressed extrathymically

1989 • 251 citations

T-cell tolerance by clonal anergy in transgenic mice with nonlymphoid expression of MHC class II I–E

1989 • 238 citations

Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells.

1989 • 156 citations

Secretion of a transplantation-related antigen

1983 • 150 citations

Transgenic Mice with I-A on Islet Cells Are Normoglycemic But Immunologically Intolerant

1989 • 135 citations

Peripheral tolerance to allogeneic class II histocompatibility antigens expressed in transgenic mice: evidence against a clonal-deletion mechanism.

1989 • 91 citations

Tissue-specific expression of allogeneic class II MHC molecules induces neither tissue rejection nor clonal inactivation of alloreactive T cells.

1990 • 56 citations

Selection of the T cell repertoire during ontogeny: Limiting dilution analysis

1982 • 39 citations

Effect of the expression of a hepatocyte-specific MHC molecule in transgenic mice on T cell tolerance.

1990 • 30 citations

Limiting dilution analysis of alloantigen-reactive T lymphocytes. III. Effect of priming on precursor frequencies.

1979 • 29 citations

Modification of the cytotoxic T cell repertoire in neonatal tolerance. Evidence for preferential survival of cells with low avidity for tolerogen.

1987 • 28 citations

Expression of hybrid class I genes of the major histocompatibility complex in mouse L cells.

1985 • 27 citations

Cytotoxic T lymphocytes from mice with soluble class I Q10 molecules in their serum are not tolerant to membrane-bound Q10.

1987 • 25 citations

Estimates of the precursor frequency of cytotoxic T lymhocytes against antigens controlled by defined regions of the H-2 gene complex: comparison of the effect of H-2 differences due to intra-H-2 recombination vs mutation.

1978 • 19 citations

The Kinetics of Antibody Production and Affinity in Balb/c Mice Immune and Partially Tolerant to the 2,4-Dinitrophenyl Determinant

1972 • 17 citations

Characterization of determinants encoded by four Qa-1 genotypes and their recognition by cloned cytotoxic T lymphocytes.

1983 • 13 citations

An immunodominant epitope present in multiple class I MHC molecules and recognized by cytotoxic T lymphocytes.

1988 • 11 citations