The Role of Putative Fibrinogen Aα-, Bβ-, and γA-chain Integrin Binding Sites in Endothelial Cell-mediated Clot Retraction

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.

1985 • 593 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors.

1987 • 428 citations

Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells

1989 • 343 citations

Role of fibrinogen alpha and gamma chain sites in platelet aggregation.

1992 • 315 citations

Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody.

1983 • 280 citations

Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs.

1987 • 223 citations

The Preparation and Properties of Human Fibrinogen of Relatively High Solubility^*

1966 • 207 citations

Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3

1985 • 175 citations

Platelet glycoproteins IIb and IIIa: evidence for a family of immunologically and structurally related glycoproteins in mammalian cells.

1986 • 157 citations

Binding of recombinant fibrinogen mutants to platelets.

1994 • 154 citations

Plasma Factor XIII Binds Specifically to Fibrinogen Molecules Containing γ‘ Chains

1996 • 142 citations

Interaction of fibrinogen with its platelet receptor. Differential effects of alpha and gamma chain fibrinogen peptides on the glycoprotein IIb-IIIa complex.

1988 • 133 citations

Impaired platelet aggregation and sustained bleeding in mice lacking the fibrinogen motif bound by integrin alpha IIb beta 3.

1996 • 132 citations

Adhesion of platelets to surface-bound fibrinogen under flow

1996 • 104 citations

Comparison of Human Plasma Fibrinogen Subfractions and Early Plasmic Fibrinogen Derivatives

1974 • 102 citations

Dissecting Clot Retraction and Platelet Aggregation

1996 • 96 citations

Anticoagulant proteases from western diamondback rattlesnake (Crotalus atrox) venom

1984 • 86 citations

SUBFRACTIONS OF HUMAN FIBRINOGEN; PREPARATION AND ANALYSIS.

1963 • 72 citations

Endothelial cell spreading on fibrin requires fibrinopeptide B cleavage and amino acid residues 15-42 of the beta chain.

1992 • 68 citations

Glycoprotein IIb/IIIa Blockade Inhibits Platelet-mediated Force Development and Reduces Gel Elastic Modulus

1995 • 67 citations

Beta 3 integrin-mediated fibrin clot retraction by nucleated cells: differing behavior of alpha IIb beta 3 and alpha v beta 3

1995 • 65 citations

Involvement of α6β3 Integrin in Mediating Fibrin Gel Retraction

1995 • 65 citations

Characterization of purified recombinant fibrinogen: partial phosphorylation of fibrinopeptide A

1993 • 62 citations

Beta 3 integrin-mediated fibrin clot retraction by nucleated cells: differing behavior of alpha IIb beta 3 and alpha v beta 3

1995 • 57 citations

Conservation of human fibrinogen conformation after cleavage of the B beta chain NH2 terminus.

1985 • 51 citations

Characterization of adhesion of “resting” and stimulated platelets to fibrinogen and its fragments

1993 • 50 citations

Fibronectin and fibrinolysis are not required for fibrin gel contraction by human skin fibroblasts

1989 • 43 citations

The residues AGDV of recombinant gamma chains of human fibrinogen must be carboxy-terminal to support human platelet aggregation.

1992 • 42 citations

B Lymphocyte Fibronectin Receptors: Expression and Utilization

1991 • 41 citations

Polymerization site in the .beta. chain of fibrin: mapping of the B.beta.1-55 sequence

1991 • 33 citations

Localization of the domains of fibrin involved in binding to platelets

1988 • 30 citations

The Residues AGDV of Recombinant γ Chains of Human Fibrinogen Must Be Carboxy-Terminal to Support Human Platelet Aggregation

1992 • 29 citations

Peptides and monoclonal antibodies which bind to platelet glycoproteins IIb and/or IIIa inhibit clot retraction

1988 • 28 citations

Endothelial cell responses to fibrin mediated by FPB cleavage and the amino terminus of the beta chain.

1993 • 25 citations

Sequence 274-368 in the beta 3-subunit of the integrin alpha IIb beta 3 provides a ligand recognition and binding domain for the gamma-chain of fibrinogen that is independent of platelet activation

1996 • 22 citations

Dissociation of Clot Retraction from Platelet Granule Fusion and Degranulation: an Ultrastructural Study of Reptilase—Human Platelet‐rich Plasma Clots

1975 • 14 citations

A Monoclonal Antibody against a peptide sequence of Fibrinogen Gamma Chain Acts as an Inhibitor of factor XIII-Mediated Crosslinking of Human Fibrin

1995 • 14 citations

Characterization of adhesion of non-exogenously stimulated and resting platelets in normal plasma to fibrinogen and its fragments

1994 • 8 citations