Morphologic evidence of a primary response of glia to kainic acid administration into the rat neostriatum; Studied in vivo and in vitro

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

1976 • 1,247 citations

Glutamine Synthetase: Glial Localization in Brain

1977 • 1,170 citations

Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

1976 • 832 citations

Kainic acid: a powerful neurotoxic analogue of glutamate

1974 • 710 citations

In situ injection of kainic acid: A new method for selectively lesioning neuronal cell bodies while sparing axons of passage

1978 • 599 citations

Metabolic Compartmentation in the Brain

1973 • 387 citations

UPTAKE AND METABOLISM OF GLUTAMATE IN ASTROCYTES CULTURED FROM DISSOCIATED MOUSE BRAIN HEMISPHERES

1977 • 343 citations

Kainate-induced degeneration of neostriatal neurons: dependency upon corticostriatal tract

1978 • 330 citations

The striatum and substantia nigra: A commentary on their relationships

1979 • 276 citations

Degeneration of hippocampal CA3 pyramidal cells induced by intraventricular kainic acid

1980 • 257 citations

Uptake of the neurotransmitter candidate glutamate by glia

1974 • 247 citations

Electron microscopy of the early postnatal development of fibrous astrocytes

1967 • 169 citations

Metabolic Compartments in the Brain: Their Properties and Relation to Morphological Structures

1973 • 166 citations

The activities in different neural cell types of certain enzymes associated with the metabolic compartmentation glutamate

1982 • 161 citations

An electron microscopic study of the neuroglia during postnatal development of the rat cerebrum

1968 • 148 citations

Neurochemical sequelae of kainate injections in corpus striatum and substantia nigra of the rat

1977 • 144 citations

PHOSPHATE ACTIVATED GLUTAMINASE ACTIVITY AND GLUTAMINE UPTAKE IN PRIMARY CULTURES OF ASTROCYTES

1979 • 138 citations

HIGH AFFINITY UPTAKE OF L‐GLUTAMATE AND L‐ASPARTATE BY GLIAL CELLS

1977 • 132 citations

Clinical, neuropathologic and pharmacologic aspects of Huntington's disease: Correlates with a new animal model

1977 • 121 citations

The ultrastructural characterization of macroglial cell types

1966 • 116 citations

Effects of cortical ablation on the neurotoxicity and receptor binding of kainic acid in striatum

1979 • 113 citations

A Simulation Study of the Metabolism and Compartmentation in Brain of Glutamate, Aspartate, the Krebs Cycle, and Related Metabolites

1966 • 111 citations

Ultrastructural analysis of kainic acid lesion to cerebellar cortex

1980 • 101 citations

NEURONAL‐GLIAL CONTRIBUTIONS TO TRANSMITTER AMINO ACID METABOLISM: STUDIES WITH KAINIC ACID‐INDUCED LESIONS OF RAT STRIATUM

1979 • 70 citations

Morphological studies on neuroglia

1981 • 62 citations

Electron microscopy of classically stained astrocytes

1967 • 57 citations

Concordance between morphological and biochemical estimates of fluid spaces in rat brain cortex slices

1974 • 57 citations

An animal model for Huntington's disease.

1979 • 43 citations

Glial changes in the progress of a chemical lesion. An electron microscopic study

1976 • 38 citations

Glial cells from normal adult rat brain established in continuous culture

1978 • 36 citations

Efflux of potassium from neurones excited by glutamate and aspartate causes a depolarization of cultured glial cells

1981 • 29 citations

The fine structure of neuroglial cells and pericytes in the primate red nucleus and substantia nigra

1970 • 26 citations

An animal model for Huntington's disease.

1979 • 25 citations

Morphological studies on neuroglia

1981 • 25 citations

Glial fibrillary changes induced by kainic acid in organotypic culture of the rat cerebellum

1982 • 7 citations

Changes of [3H]colchicine binding and protein synthesis in the rat striatum following kainic acid lesions

1978 • 7 citations

Protein and RNA synthesis in kainic acid-injected striata

1979 • 7 citations

Macrophage Response and Gliosis induced by Intraventricular Injection of Kainic Acid

1979 • 1 citations