Osteogenin and recombinant bone morphogenetic protein 2B are chemotactic for human monocytes and stimulate transforming growth factor beta 1 mRNA expression.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Bone: Formation by Autoinduction

1965 • 5,498 citations

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

LEUKOCYTE LOCOMOTION AND CHEMOTAXIS

1973 • 1,709 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

Recombinant human bone morphogenetic protein induces bone formation.

1990 • 1,538 citations

Some recent advances in the chemistry and biology of transforming growth factor-beta.

1987 • 1,308 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Biochemical Sequences in the Transformation of Normal Fibroblasts in Adolescent Rats

1972 • 815 citations

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

1987 • 791 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur.

1990 • 734 citations

Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor

1985 • 633 citations

In VivoStimulation of Bone Formation by Transforming Growth Factor-β

1989 • 592 citations

Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation.

1981 • 585 citations

Transforming growth factor β (TGFβ) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts

1987 • 579 citations

Osteoblasts synthesize and respond to transforming growth factor-type beta (TGF-beta) in vitro.

1987 • 561 citations

OP-1 cDNA encodes an osteogenic protein in the TGF-beta family.

1990 • 554 citations

Cartilage-inducing factor-A. Apparent identity to transforming growth factor-beta.

1986 • 533 citations

Purification and characterization of two cartilage-inducing factors from bovine demineralized bone.

1985 • 503 citations

Cell Biology and Biochemistry of Endochondral Bone Development

1981 • 487 citations

Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues

1984 • 486 citations

Characterization of a membrane receptor for transforming growth factor-beta in normal rat kidney fibroblasts.

1984 • 477 citations

Mesoderm Induction in Amphibians: the Role of TGF-β2-Like Factors

1988 • 452 citations

Purification and Partial Amino Acid Sequence of Osteogenin, a Protein Initiating Bone Differentiation

1989 • 405 citations

Transforming growth factor β type 1 binds to collagen IV of basement membrane matrix: Implications for development

1991 • 350 citations

Cartilage-inducing factor-B is a unique protein structurally and functionally related to transforming growth factor-beta.

1987 • 336 citations

Isolation of osteogenin, an extracellular matrix-associated, bone-inductive protein, by heparin affinity chromatography.

1987 • 334 citations

Chemoattractant Receptors on Phagocytic Cells

1984 • 236 citations

Transforming growth factor-beta (TGFβ) is chemotactic for human monocytes and induces their expression of angiogenic activity

1988 • 233 citations

Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin.

1989 • 224 citations

Isolation of human mononuclear cell subsets by counterflow centrifugal elutriation (CCE)

1984 • 218 citations

Transforming growth factor‐beta modulates the expression of osteoblast and chondroblast phenotypes in vitro

1988 • 216 citations

TGF-β Regulates Production of Growth Factors and TGF-β by Human Peripheral Blood Monocytes

1990 • 178 citations

Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagen.

1990 • 176 citations

Chemotactic response of osteoblastlike cells to transforming growth factorβ

1990 • 176 citations

Bone-Inducing Activity of Mature BMP-2b Produced from a Hybrid BMP-2a/2b Precursor

1991 • 172 citations

Accumulation, localization, and compartmentation of transforming growth factor beta during endochondral bone development.

1988 • 154 citations

Macrophage Production of TGF-? and Regulation by TGF-?

1990 • 149 citations

Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-beta

1988 • 118 citations

Immunofluorescent localization of type IV collagen and laminin during endochondral bone differentiation and regulation by pituitary growth hormone

1980 • 107 citations

Role of the thymus in streptococcal cell wall-induced arthritis and hepatic granuloma formation. Comparative studies of pathology and cell wall distribution in athymic and euthymic rats.

1985 • 95 citations

Identification and characterization of cellular binding proteins (receptors) for recombinant human bone morphogenetic protein 2B, an initiator of bone differentiation cascade.

1991 • 63 citations

Co-expression of chemotactic ligand receptors on human peripheral blood monocytes.

1987 • 31 citations

The Occurrence of Accessory Immunologic Cells in Bone Induction

1991 • 18 citations