Hepatitis B virus sequence changes evolving in liver transplant recipients with fulminant hepatitis

Vaccine-induced escape mutant of hepatitis B virus

1990 • 1,081 citations

Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli

1979 • 992 citations

Mutations in the Precore Region of Hepatitis B Virus DNA in Patients with Fulminant and Severe Hepatitis

1991 • 536 citations

A Hepatitis B Virus Mutant Associated with an Epidemic of Fulminant Hepatitis

1991 • 468 citations

Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice.

1987 • 353 citations

Hepatitis B Virus Strains with Mutations in the Core Promoter in Patients with Fulminant Hepatitis

1995 • 292 citations

Fulminant hepatitis B: Induction by hepatitis B virus mutants defective in the precore region and incapable of encoding E antigen

1991 • 255 citations

Host-independent evolution and a genetic classification of the hepadnavirus family based on nucleotide sequences.

1989 • 221 citations

Genomic heterogeneity of hepatitis B virus in a 54-year-old woman who contracted the infection through materno-fetal transmission.

1987 • 218 citations

Loss of the common "A" determinant of hepatitis B surface antigen by a vaccine-induced escape mutant.

1992 • 211 citations

Fulminant reactivation of hepatitis B due to envelope protein mutant that escaped detection by monoclonal HBsAg ELISA

1995 • 208 citations

High-level expression of hepatitis B viral antigens in fibrosing cholestatic hepatitis

1992 • 192 citations

Mutations within the S Gene of Hepatitis B Virus Transmitted from Mothers to Babies Immunized with Hepatitis B Immune Globulin and Vaccine

1992 • 187 citations

Genetic alterations in the gene encoding the major HBsAg: DNA and immunological analysis of recurrent HBsAg derived from monoclonal antibody—treated liver transplant patients

1992 • 183 citations

Enhanced replication of a hepatitis B virus mutant associated with an epidemic of fulminant hepatitis

1994 • 182 citations

Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis

1991 • 169 citations

The glucocorticoid receptor recognizes a specific nucleotide sequence in hepatitis B virus DNA causing increased activity of the HBV enhancer

1988 • 167 citations

Hepadnavirus P protein utilizes a tyrosine residue in the TP domain to prime reverse transcription

1994 • 164 citations

Patterns of hepatitis delta virus reinfection and disease in liver transplantation

1991 • 153 citations

Independent emergence of a vaccine-induced escape mutant of hepatitis B virus

1991 • 146 citations

Mutations in core nucleotide sequence of hepatitis B virus correlate with fulminant and severe hepatitis.

1993 • 141 citations

Infectious Hepatitis B Virus Variant Defective in Pre-S2 Protein Expression in a Chronic Carrier

1993 • 139 citations

The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host

1992 • 137 citations

Mutational analysis of the cysteine residues in the hepatitis B virus small envelope protein

1993 • 128 citations

The Complete Nucleotide Sequence of a Pre-core Mutant of Hepatitis B Virus Implicated in Fulminant Hepatitis and Its Biological Characterization in Chimpanzees

1993 • 120 citations

Gly145 to Arg substitution in HBs antigen of immune escape mutant of hepatitis B virus

1992 • 115 citations

Nucleotide sequence analysis of the precore region in patients with fulminant hepatitis B in the United States

1993 • 104 citations

Intracellular retention of surface protein by a hepatitis B virus mutant that releases virion particles

1996 • 101 citations

The structure of hepadnaviral core antigens. Identification of free thiols and determination of the disulfide bonding pattern.

1992 • 97 citations

A Common-Source Outbreak of Fulminant Hepatitis B in a Hospital

1989 • 93 citations

Hepatitis B virus genomes of patients with fulminant hepatitis do not share a specific mutation

1996 • 92 citations

Hepatitis B virus precore mutant infection is associated with severe recurrent disease after liver transplantation

1995 • 92 citations

LONG-TERM FOLLOW-UP OF HEPATITIS B VIRUS-INFECTED RECIPIENTS AFTER ORTHOTOPIC LIVER TRANSPLANTATION

1994 • 90 citations

Recurrence of hepatitis B and delta hepatitis after orthotopic liver transplantation.

1992 • 89 citations

Hepatitis B virus precore mutation and fulminant hepatitis in the United States. A polymerase chain reaction-based assay for the detection of specific mutation.

1994 • 88 citations

Hepatitis B virus mutations in the pre-S genome before and after liver transplantatio

1996 • 82 citations

Reactivation of precore mutant hepatitis B virus leading to fulminant hepatic failure following cytotoxic treatment

1992 • 80 citations

Hepatitis B virus surface mutations associated with infection after liver transplantation

1996 • 77 citations

Fulminant hepatitis related to transmission of hepatitis B variants with precore mutations between spouses

1992 • 74 citations

Fulminant hepatitis associated with hepatitis B virus e antigen–negative infection: Importance of host factors

1995 • 72 citations

Increased hepatocyte expression of hepatitis B virus transcription in patients with features of fibrosing cholestatic hepatitis

1993 • 71 citations

Association of hepatitis B viral precore mutations with fulminant hepatitis B in Japan

1991 • 69 citations

FULMINANT HEPATITIS B IN SUCCESSIVE FEMALE SEXUAL PARTNERS OF TWO ANTI-HBe-POSITIVE MALES

1986 • 66 citations

Low prevalence of precore mutations in hepatitis B virus DNA in fulminant hepatitis type B in France

1993 • 64 citations

MODULATION OF HEPATITIS B VIRAL ANTIGEN EXPRESSION BY IMMUNOSUPPRESSIVE DRUGS IN PRIMARY HEPATOCYTE CULTURE

1992 • 63 citations

Hepatitis B virus core antigen (HBc Ag) accumulation in an HBV nonproducer clone of HepG2-transfected cells is associated with cytopathic effect

1990 • 62 citations

An intramolecular disulfide bridge between Cys-7 and Cys61 determines the structure of the secretory core gene product (e antigen) of hepatitis B virus

1993 • 59 citations

Impact of immunoprophylaxis and patient selection on outcome of transplantation for HBsAg-positive liver recipients

1994 • 56 citations

Fulminant hepatitis B in infants born to anti-HBe hepatitis B carrier mothers.

1992 • 50 citations

Fulminant hepatic failure in non-Hodgkin lymphoma patients treated with chemotherapy

1992 • 48 citations

Selective transmission of variant genomes from mother to infant in neonatal fulminant hepatitis B

1995 • 45 citations

Key Role of a CCAAT Element in Regulating Hepatitis B Virus Surface Protein Expression

1995 • 43 citations

Emergence of hepatitis B virus S gene mutant in a liver transplant recipient

1995 • 39 citations

Patterns and mechanisms of hepatitis B/hepatitis D reinfection after liver transplantation

1993 • 8 citations