Functional soluble CD100/Sema4D released from activated lymphocytes: possible role in normal and pathologic immune responses

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.

1978 • 1,619 citations

Murine Models of Systemic Lupus Erythematosus

1985 • 1,572 citations

Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

1993 • 1,146 citations

Protection from Fas-Mediated Apoptosis by a Soluble Form of the Fas Molecule

1994 • 1,120 citations

Plexins Are a Large Family of Receptors for Transmembrane, Secreted, and GPI-Anchored Semaphorins in Vertebrates

1999 • 1,118 citations

The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

1993 • 930 citations

From Systemic T Cell Self-Reactivity to Organ-Specific Autoimmune Disease via Immunoglobulins

1999 • 689 citations

Semaphorin III is needed for normal patterning and growth of nerves, bones and heart

1996 • 570 citations

Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs

1995 • 412 citations

Diverse Cell Surface Protein Ectodomains Are Shed by a System Sensitive to Metalloprotease Inhibitors

1996 • 404 citations

Fasciclin IV: Sequence, expression, and function during growth cone guidance in the grasshopper embryo

1992 • 369 citations

Metalloprotease-Disintegrins: Links to Cell Adhesion and Cleavage of TNFα and Notch

1997 • 363 citations

Identification of CD72 as a Lymphocyte Receptor for the Class IV Semaphorin CD100

2000 • 343 citations

Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation.

1996 • 254 citations

The Class IV Semaphorin CD100 Plays Nonredundant Roles in the Immune System

2000 • 250 citations

Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits.

1987 • 249 citations

Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns.

1996 • 238 citations

The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing

1997 • 238 citations

Expression, Structure, and Function of the CD23 Antigen

1991 • 207 citations

CD72-Deficient Mice Reveal Nonredundant Roles of CD72 in B Cell Development and Activation

1999 • 199 citations

Distinct 3p21.3 deletions in lung cancer and identification of a new human semaphorin.

1996 • 193 citations

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

1996 • 170 citations

CD27: marker and mediator of T-cell activation?

1994 • 169 citations

Sjögren's syndrome in MRL/l and MRL/n mice

1984 • 161 citations

The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation.

1998 • 157 citations

Cutting Edge: The B Cell Surface Protein CD72 Recruits the Tyrosine Phosphatase SHP-1 upon Tyrosine Phosphorylation

1998 • 141 citations

Increased surface expression of a newly identified 150-kDa dimer early after human T lymphocyte activation.

1992 • 140 citations

Identification of a Novel Transmembrane Semaphorin Expressed on Lymphocytes

1996 • 108 citations

Shedding of the CD44 adhesion molecule from leukocytes induced by anti-CD44 monoclonal antibody simulating the effect of a natural receptor ligand.

1992 • 104 citations

A murine nephritogenic monoclonal anti‐DNA autoantibody binds directly to mouse laminin, the major non‐collagenous protein component of the glomerular basement membrane

1989 • 99 citations

CD100 is a leukocyte semaphorin

1998 • 99 citations

Axon guidance: A compelling case for repelling growth cones

1995 • 95 citations

A naturally occurring soluble isoform of murine Fas generated by alternative splicing.

1995 • 93 citations

Semaphorin Signaling

1999 • 87 citations

CD100 is associated with CD45 at the surface of human T lymphocytes. Role in T cell homotypic adhesion.

1996 • 76 citations

Expression of VCAM-1 (CD106) by a subset of TCR gamma delta-bearing lymphocyte clones. Involvement of a metalloprotease in the specific hydrolytic release of the soluble isoform.

1995 • 68 citations

Activation signals are delivered through two distinct epitopes of CD100, a unique 150 kDa human lymphocyte surface structure previously defined by BB18 mAb

1995 • 67 citations

Reactive lymphocytes in lacrimal gland and vasculitic renal lesions of autoimmune MRL/lpr mice express L3T4.

1987 • 66 citations

Soluble CD21 induces activation and differentiation of human monocytes through binding to membrane CD23

1998 • 22 citations

A monoclonal DNA-binding autoantibody causes a deterioration in renal function in MRL mice with lupus disease.

1988 • 15 citations

Partial purification and characterization of a tumor necrosis factor‐α converting activity

1997 • 14 citations