12-O-Tetradecanoylphorbol-13-acetate Induces Epstein–Barr Virus Reactivation via NF-κB and AP-1 as Regulated by Protein Kinase C and Mitogen-Activated Protein Kinase

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

NITRIC OXIDE: A Physiologic Messenger Molecule

1994 • 2,299 citations

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.

1994 • 2,216 citations

Epstein-Barr virus and its replication

1996 • 1,621 citations

The regulation of transcription by phosphorylation

1992 • 1,316 citations

NF-κB: A lesson in family values

1995 • 1,266 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

Persisting oncogenic herpesvirus induced by the tumour promoter TPA

1978 • 632 citations

Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA.

1985 • 454 citations

The Epstein–Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-κB

1997 • 397 citations

Both Epstein-Barr virus (EBV)-encoded trans-acting factors, EB1 and EB2, are required to activate transcription from an EBV early promoter.

1986 • 359 citations

Epstein-Barr virus BZLF1 trans-activator specifically binds to a consensus AP-1 site and is related to c-fos.

1989 • 334 citations

Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade

1997 • 320 citations

trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment

1986 • 278 citations

Stimulation of NF-kappa B-mediated transcription by mutant derivatives of the latent membrane protein of Epstein-Barr virus

1995 • 277 citations

Activation of the cJun N-terminal kinase (JNK) pathway by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1)

1998 • 269 citations

Oxidative Stress Induces NFκB DNA Binding and Inducible NOS mRNA in Human Epithelial Cells

1994 • 263 citations

Cross‐linking of cell surface immunoglobulins induces epstein‐barr virus in burkitt lymphoma lines

1984 • 253 citations

The Epstein–Barr virus LMP1 amino acid sequence that engages tumor necrosis factor receptor associated factors is critical for primary B lymphocyte growth transformation

1997 • 224 citations

Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Activates the JNK Pathway through Its Extreme C Terminus via a Mechanism Involving TRADD and TRAF2

1999 • 208 citations

The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions

1990 • 205 citations

Neuronal (type I) nitric oxide synthase regulates nuclear factorκB activity and immunologic (type II) nitric oxide synthase expression

1997 • 202 citations

The Epstein-Barr virus Zta transactivator: a member of the bZIP family with unique DNA-binding specificity and a dimerization domain that lacks the characteristic heptad leucine zipper motif

1990 • 199 citations

Chloromethyl ketones block induction of nitric oxide synthase in murine macrophages by preventing activation of nuclear factor-kappa B.

1995 • 167 citations

The Epstein-Barr virus early protein EB1 activates transcription from different responsive elements including AP-1 binding sites.

1989 • 157 citations

The BZLF1 protein of EBV has a coiled coil dimerisation domain without a heptad leucine repeat but with homology to the C/EBP leucine zipper.

1991 • 119 citations

Protein Kinase C η Mediates Lipopolysaccharide-induced Nitric-oxide Synthase Expression in Primary Astrocytes

1998 • 106 citations

Aspirin inhibits tumor cell invasiveness induced by Epstein-Barr virus latent membrane protein 1 through suppression of matrix metalloproteinase-9 expression.

2000 • 106 citations

Evidence for coiled-coil dimer formation by an Epstein-Barr virus transactivator that lacks a heptad repeat of leucine residues.

1990 • 102 citations

Epstein-Barr virus BZLF1 trans activator induces the promoter of a cellular cognate gene, c-fos

1990 • 74 citations

Regulation of the BZLF1 Promoter of Epstein-Barr Virus by Second Messengers in Anti-immunoglobulin-Treated B Cells

1994 • 64 citations

Characterization of the ZI domains in the Epstein-Barr virus BZLF1 gene promoter: role in phorbol ester induction

1996 • 54 citations

Nitric Oxide Down-Regulates Epstein–Barr Virus Reactivation in Epithelial Cell Lines

1999 • 52 citations

Characterization of Proteins Binding to the ZII Element in the Epstein–Barr Virus BZLF1 Promoter: Transactivation by ATF1

1997 • 48 citations

Differential expression and regulation of chemokines JE, KC, and IP-10 gene in primary cultured murine hepatocytes

1999 • 44 citations

Post-Isolation Inducible Nitric Oxide Synthase Gene Expression Due to Collagenase Buffer Perfusion and Characterization of the Gene Regulation in Primary Cultured Murine Hepatocytes

1998 • 41 citations

Establishment of Epstein‐Barr Virus‐positive Human Gastric Epithelial Cell Lines

1998 • 40 citations

Productive Infection of Epstein–Barr Virus (EBV) in EBV-Genome-Positive Epithelial Cell Lines (GT38 and GT39) Derived from Gastric Tissues

1998 • 37 citations

Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.

1999 • 34 citations

The interaction of mitogen-activated protein kinases to Epstein-Barr virus activation in Akata cells.

1999 • 27 citations

TPA and cycloheximide modulate the activation of NF‐κB and the induction and stability of nitric oxide synthase transcript in primary neonatal rat hepatocytes

1996 • 16 citations

Tumorigenesis of Epstein–Barr Virus-Positive Epithelial Cell Lines Derived from Gastric Tissues in the SCID Mouse

2000 • 15 citations