Insulin and platelet-derived growth factor acutely stimulate glucose transport in 3T3-L1 fibroblasts independently of protein kinase C

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

1986 • 999 citations

Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat.

1991 • 874 citations

Molecular Biology of Mammalian Glucose Transporters

1990 • 852 citations

Elevated Levels of Glucose Transport and Transporter Messenger RNA Are Induced by ras or src Oncogenes

1987 • 789 citations

Regulation of inositol phospholipid-specific phospholipase C isozymes.

1992 • 740 citations

Identification of a novel gene encoding an insulin-responsive glucose transporter protein

1989 • 601 citations

Regulation of Phospholipase C-γ1 by Profilin and Tyrosine Phosphorylation

1991 • 532 citations

Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes.

1985 • 512 citations

Protein kinase C activation by diacylglycerol second messengers

1986 • 498 citations

Potent selective inhibitors of protein kinase C

1989 • 482 citations

Growth factor-stimulated protein phosphorylation in 3T3-L1 cells. Evidence for protein kinase C-dependent and -independent pathways.

1985 • 351 citations

c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF

1985 • 331 citations

Facilitative glucose transporters: an expanding family

1990 • 316 citations

Expression of human glucose transporters in Xenopus oocytes: kinetic characterization and substrate specificities of the erythrocyte, liver, and brain isoforms

1991 • 298 citations

The influence of basic residues on the substrate specificity of protein kinase C.

1987 • 287 citations

Growth factors rapidly induce expression of the glucose transporter gene.

1988 • 263 citations

Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich protein.

1990 • 247 citations

Identification of an intracellular pool of glucose transporters from basal and insulin-stimulated rat skeletal muscle.

1990 • 246 citations

Activation of phospholipase D by protein kinase C. Evidence for a phosphorylation-independent mechanism.

1992 • 237 citations

Regulation of Protein Kinase C by Nerve Growth Factor, Epidermal Growth Factor, and Phorbol Esters in PC12 Pheochromocytoma Cells

1989 • 219 citations

Phosphatidylinositol-Glycan Anchors of Membrane Proteins: Potential Precursors of Insulin Mediators

1988 • 199 citations

Inhibition of glucose transport in the human erythrocyte by cytochalasin B

1973 • 172 citations

Sugar Transport in Chick Embryo Fibroblasts

1974 • 160 citations

Effects of insulin and protein synthesis inhibitors on phospholipid metabolism, diacylglycerol levels, and pyruvate dehydrogenase activity in BC3H-1 cultured myocytes.

1984 • 136 citations

Platelet-derived growth factor regulates glucose transporter expression.

1988 • 117 citations

Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation.

1990 • 110 citations

Activation of glucose transport in skeletal muscle by phospholipase C and phorbol ester

1989 • 92 citations

Development of an intracellular pool of glucose transporters in 3T3-L1 cells.

1992 • 88 citations

Multiple control mechanisms underlie initiation of growth in animal cells

1974 • 82 citations

A method for measuring protein kinase C activity in permeabilized T lymphocytes by using peptide substrates. Evidence for multiple pathways of kinase activation

1990 • 81 citations

Insulin stimulation of glucose uptake can be mediated by diacylglycerol in adipocytes

1988 • 79 citations

Insulin-induced glycerolipid mediators and the stimulation of glucose transport in BC3H-1 myocytes.

1988 • 67 citations

Insulin activation of protein kinase C: a reassessment

1991 • 65 citations

Insulin-induced translocation of glucose transporters to the plasma membrane precedes full stimulation of hexose transport

1988 • 64 citations

Regulation of glucose transport activity and expression of glucose transporter mRNA by serum, growth factors and phorbol ester in quiescent mouse fibroblasts

1989 • 63 citations

The regulation of phospholipase D activity and its role in sn-1,2-diradylglycerol formation in bombesin- and phorbol 12-myristate 13-acetate-stimulated Swiss 3T3 cells

1991 • 62 citations

Stimulation of mitogenesis and glucose transport by 1-monooleoylglycerol in Swiss 3T3 fibroblasts.

1988 • 52 citations

Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice

1992 • 51 citations

Translocation of the brain-type glucose transporter largely accounts for insulin stimulation of glucose transport in BC3H-1 myocytes

1990 • 47 citations

Inhibition or down-regulation of protein kinase C attenuates late phase p70s6k activation induced by epidermal growth factor but not by platelet-derived growth factor or insulin.

1992 • 44 citations

Immunological evidence that insulin activates protein kinase C in BC3H‐1 myocytes

1989 • 41 citations

Phorbol ester only partially mimics the effects of insulin on glucose transport and glucose-transporter distribution in 3T3-L1 adipocytes

1991 • 39 citations

Insulin-like effects of epidermal growth factor and insulin-like growth factor-I on [3H]2-deoxyglucose uptake, diacylglycerol generation and protein kinase C activation in BC3H-1 myocytes

1989 • 33 citations

Differential effects of pertussis toxin on insulin-stimulated phosphatidylcholine hydrolysis and glycerolipid synthesis de novo. Studies in BC3H-1 myocytes and rat adipocytes

1991 • 21 citations

Mutated Insulin Receptor Val996 Reduces Insulin-Dependent Generation of Inositol Glycan and Diacylglycerol

1992 • 16 citations

Studies of in vivo phosphorylated proteins in BC3H‐1 myocytes suggest that protein kinase C is involved in insulin action

1989 • 16 citations