Effect of vitamin E on aortic lipid oxidation and intimal proliferation after arterial injury in cholesterol-fed rabbits

Beyond Cholesterol

1989 • 6,533 citations

Vitamin E Consumption and the Risk of Coronary Heart Disease in Men

1993 • 2,363 citations

Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

1996 • 2,163 citations

Vitamin E Consumption and the Risk of Coronary Disease in Women

1993 • 2,158 citations

Vitamin E Supplementation and Cardiovascular Events in High-Risk Patients

2000 • 1,945 citations

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

Antioxidants and Atherosclerotic Heart Disease

1997 • 1,390 citations

The role of oxidized lipoproteins in atherogenesis

1996 • 1,382 citations

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

1981 • 1,037 citations

Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression.

1992 • 653 citations

Probucol and Multivitamins in the Prevention of Restenosis after Coronary Angioplasty

1997 • 572 citations

Oxidants and antioxidants in the pathogenesis of atherosclerosis: implications for the oxidized low density lipoprotein hypothesis

1998 • 471 citations

Detection and characterization of lipid hydroperoxides at picomole levels by high-performance liquid chromatography

1987 • 362 citations

Human Atherosclerotic Plaque Contains Both Oxidized Lipids and Relatively Large Amounts of α-Tocopherol and Ascorbate

1995 • 357 citations

[50] Rapid isolation of lipoproteins and assessment of their peroxidation by high-performance liquid chromatography postcolumn chemiluminescence

1994 • 313 citations

Lipid in the aortic intima the correlation of morphological and chemical characteristics

1967 • 266 citations

Coronary Angioplasty Results in Leukocyte and Platelet Activation With Adhesion Molecule Expression

1997 • 243 citations

7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque

1997 • 240 citations

Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.

1994 • 229 citations

7 beta-hydroperoxycholest-5-en-3 beta-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein.

1994 • 208 citations

Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbits.

1993 • 204 citations

Vascular incorporation of alpha-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation.

1996 • 203 citations

Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation.

1995 • 202 citations

Determinants of Vascular Smooth Muscle Cell Apoptosis After Balloon Angioplasty Injury

1999 • 188 citations

Probucol decreases neointimal formation in a swine model of coronary artery balloon injury. A possible role for antioxidants in restenosis.

1993 • 151 citations

Combination of Vitamins C and E Alters the Response to Coronary Balloon Injury in the Pig

1995 • 142 citations

Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities

1994 • 132 citations

Probucol inhibits neointimal thickening and macrophage accumulation after balloon injury in the cholesterol-fed rabbit.

1992 • 130 citations

Antioxidant treatment inhibits the development of intimal thickening after balloon injury of the aorta in hypercholesterolemic rabbits.

1993 • 119 citations

Dissociation of atherogenesis from aortic accumulation of lipid hydro(pero)xides in Watanabe heritable hyperlipidemic rabbits

1999 • 113 citations

Relation of Vascular Oxidative Stress, α-Tocopherol, and Hypercholesterolemia to Early Atherosclerosis in Hamsters

1995 • 107 citations

Coexistence of Oxidized Lipids and α-Tocopherol in All Lipoprotein Density Fractions Isolated From Advanced Human Atherosclerotic Plaques

1999 • 106 citations

Inhibition by a coantioxidant of aortic lipoprotein lipid peroxidation and atherosclerosis in apolipoprotein E and low density lipoprotein receptor gene double knockout mice

1999 • 99 citations

Site-Specific Antiatherogenic Effect of Probucol in Apolipoprotein E–Deficient Mice

2000 • 93 citations

Effect of alpha-tocopherol on restenosis after angioplasty in a model of experimental atherosclerosis.

1995 • 90 citations

Preventive effects of probucol on restenosis after percutaneous transluminal coronary angioplasty

1996 • 83 citations

Potentiation of atherosclerotic lesions in rabbits by a high dietary level of vitamin E

1989 • 66 citations

Vitamin E inhibits the intimal response to balloon catheter injury in the carotid artery of the cholesterol-fed rat

1995 • 60 citations

The Oxidative Modification Hypothesis of Atherogenesis

2000 • 55 citations

Low-Dose α-Tocopherol Improves and High-Dose α- Tocopherol Worsens Endothelial Vasodilator Function in Cholesterol-Fed Rabbits

1994 • 54 citations

Oxidative stress and vascular disease

2001 • 44 citations

Impact of vitamin E supplement in standard laboratory animal diet on microvascular manifestation of ischemia/reperfusion injury

1995 • 36 citations

Contribution of the endothelium to intimal thickening in normocholesterolemic and hypercholesterolemic rabbits.

1992 • 29 citations

Macrophage foam cells from human aortic fatty streaks take up β-VLDL and acetylated LDL in primary culture

1989 • 28 citations

Do vitamin E supplements in diets for laboratory animals jeopardize findings in animal models of disease?

1999 • 23 citations

Inhibitory effect of a single local probucol administration on neointimal formation in balloon-injured rat carotid artery

1995 • 21 citations

Antioxidants and Restenosis: Animal Studies

2000 • 6 citations

Identification of Oxidatively Modified Lipids in Atherosclerotic Lesions of Human Aortas

1992 • 5 citations