The assessment of proliferating cell nuclear antigen immunohistochemical staining in small hepatocellular carcinoma and its relationship to histologic characteristics and prognosis

TNM Classification of Malignant Tumours

1987 • 16,209 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

Primary carcinoma of the liver.A study of 100 cases among 48,900 necropsies

1954 • 2,755 citations

Monoclonal Antibody to 5-Bromo- and 5-Iododeoxyuridine: A New Reagent for Detection of DNA Replication

1982 • 2,648 citations

Cyclin/PCNA is the auxiliary protein of DNA polymerase-δ

1987 • 1,766 citations

Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA) structural conservation and the detection of a nucleolar form

1990 • 736 citations

Pathology of hepatocellular carcinoma in Japan: 232 consecutive cases autopsied in ten years

1983 • 591 citations

Analysis of proliferative grade using anti-PCNA/cyclin monoclonal antibodies in fixed, embedded tissues. Comparison with flow cytometric analysis.

1989 • 582 citations

A search for differential polypeptide synthesis throughout the cell cycle of HeLa cells.

1980 • 465 citations

Pathology of small hepatocellular carcinoma. A proposal for a new gross classification

1987 • 358 citations

A nuclear antigen associated with cell proliferation and blast transformation.

1981 • 333 citations

Resection of hepatocellular carcinomas

1990 • 307 citations

Immunohistochemical detection of proliferating cell nuclear antigen in solid human malignancies.

1987 • 304 citations

Clinical Features and Long-term Prognosis

1987 • 299 citations

Cyclin/PCNA immunostaining as an alternative to tritiated thymidine pulse labelling for marking S phase cells in paraffin sections from animal and human tissues

1989 • 295 citations

Monoclonal antibodies to a nuclear protein (PCNA/cyclin) associated with DNA replication

1987 • 268 citations

The assessment of proliferating cell nuclear antigen (PCNA) immunostaining in primary gastrointestinal lymphomas and its relationship to histological grade, S + G2 + M phase fraction (flow cytometric analysis) and prognosis

1991 • 220 citations

Predictive factors for intrahepatic recurrence of hepatocellular carcinoma after partial hepatectomy

1992 • 200 citations

Flow cytometric multiparameter analysis of proliferating cell nuclear antigen/cyclin and Ki-67 antigen: A new view of the cell cycle

1990 • 194 citations

Prognostic value of proliferating cell nuclear antigen in gastric carcinoma.

1991 • 190 citations

Comparative assessment of proliferation and DNA content in breast carcinoma by image analysis and flow cytometry.

1990 • 168 citations

Clinicopathologic features of encapsulated hepatocellular carcinoma.A study of 26 cases

1977 • 165 citations

Intracellular localization of human DNA polymerase alpha with monoclonal antibodies.

1982 • 161 citations

Growth fraction estimation of malignant lymphomas in formalin-fixed paraffin-embedded tissue using anti-PCNA/Cyclin 19A2. Correlation with Ki-67 labeling.

1991 • 148 citations

Flow cytometric dna analysis of hepatocellular carcinoma

1991 • 111 citations

A comparison of proliferating cell nuclear antigen (PCNA) immunostaining, nucleolar organizer region (AGNOR) staining, and histological grading in gastrointestinal stromal tumours

1992 • 108 citations

Tumor invasiveness and prognosis in resected hepatocellular carcinoma.Clinical and pathogenetic implications

1988 • 108 citations

A method of labeling tissues with tritiated thymidine in vitro and its use in comparing rates of cell proliferation in duct epithelium, fibroadenoma, and carcinoma of human breast

1961 • 105 citations

In vitro uptake of bromodeoxyuridine by human hepatocellular carcinoma and its relation to histopathologic findings and biologic behavior

1991 • 28 citations

DNA polymerase alpha positive-cell rate in colorectal cancer and its relationship to prognosis

1992 • 10 citations