Effects of tepoxalin, a dual inhibitor of cyclooxygenase/5-lipoxygenase, on events associated with NSAID-induced gastrointestinal inflammation

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1979 • 27,693 citations

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process

1990 • 563 citations

Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats.

1993 • 344 citations

Neutrophils roll on E-selectin.

1993 • 339 citations

Indomethacin-induced leukocyte adhesion in mesenteric venules: role of lipoxygenase products

1992 • 206 citations

Role of endothelial adhesion molecules in NSAID-induced gastric mucosal injury

1993 • 187 citations

Enhanced gastric mucosal leukotriene B4 synthesis in patients taking non-steroidal anti-inflammatory drugs.

1993 • 151 citations

Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.

1994 • 126 citations

A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents

1979 • 94 citations

Gastric ulceration: critical events at the neutrophil–endothelium interface

1993 • 81 citations

Early histological features of small intestinal injury induced by indomethacin

1993 • 80 citations

Acute indomethacin-induced jejunal injury in the rat: Early morphological and biochemical changes

1994 • 78 citations

Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: Anti-inflammatory without gastropathy?

1993 • 74 citations

Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damage

1993 • 67 citations

Do infiltrating neutrophils contribute to the pathogenesis of indomethacin induced ulceration of the rat gastric antrum?

1993 • 54 citations

Tepoxalin, a novel immunosuppressive agent with a different mechanism of action from cyclosporin A.

1994 • 26 citations

Comparison of the ulcerogenic properties of tepoxalin with those of non-steroidal anti-inflammatory drugs (NSAIDs)

1991 • 20 citations

Reduction of adverse effects of indomethacin by anti-allergic drugs in rat stomachs.

1992 • 19 citations

Leukocyte Adhesion and Emigration in Inflammationa

1992 • 17 citations

Leukotrienes do not contribute to the pathogenesis of indomethacin-induced ulceration of the gastric antrum in the re-fed rat

1994 • 8 citations

Chronic leukotriene inhibition in the rat fails to modify the toxicological effects of a cyclooxygenase inhibitor

1993 • 4 citations