Rotenone induces non‐specific central nervous system and systemic toxicity
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References (52)
The Rat Brain in Stereotaxic Coordinates
1982 • 53,055 citations
The rat brain in stereotaxic coordinates
1983 • 28,962 citations
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
2000 • 3,559 citations
Oxidative stress in Parkinson's disease
2003 • 2,001 citations
Dopamine Neuron Agenesis in Nurr1-Deficient Mice
1997 • 1,075 citations
Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
1997 • 994 citations
Environmental Risk Factors and Parkinson's Disease: Selective Degeneration of Nigral Dopaminergic Neurons Caused by the Herbicide Paraquat
2002 • 804 citations
Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons
1998 • 725 citations
Subcutaneous Rotenone Exposure Causes Highly Selective Dopaminergic Degeneration and α-Synuclein Aggregation
2002 • 695 citations
Demonstration of a unique population of neurons with NADPH-diaphorase histochemistry
1983 • 687 citations
The Herbicide Paraquat Causes Up-regulation and Aggregation of α-Synuclein in Mice
2002 • 644 citations
The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living
1998 • 630 citations
Experimental models of Parkinson's disease
2001 • 617 citations
Environmental risk factors and Parkinson's disease
1997 • 605 citations
Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats
2002 • 457 citations
Environmental Risk Factors and Parkinson's Disease: A Metaanalysis
2001 • 435 citations
Possible environmental, occupational, and other etiologic factors for Parkinson's disease
1996 • 424 citations
Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease.
1999 • 422 citations
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
2001 • 360 citations
Excitotoxic neuronal death in the immature brain is an apoptosis-necrosis morphological continuum
1997 • 333 citations
Glial cells and inflammation in parkinson's disease: A role in neurodegeneration?
1998 • 328 citations
Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats
2003 • 323 citations
Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry
1991 • 290 citations
Environmental antecedents of young‐onset Parkinson's disease
1993 • 231 citations
New expression of myelomonocytic antigens by microglia and perivascular cells following lethal motor neuron injury
1990 • 213 citations
Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell‐specific manner
2003 • 205 citations
Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra
1997 • 200 citations
Chemical anatomy of striatal interneurons in normal individuals and in patients with Huntington’s disease
2000 • 195 citations
Hypertensive putaminal hemorrhage
1977 • 188 citations
Reduced Nurrl Expression Increases the Vulnerability of Mesencephalic Dopamine Neurons to MPTP‐Induced Injury
1999 • 183 citations
Stress and Interleukin‐1 β‐Induced Activation of c‐fos, NGFI‐B ann CRF Gene Expression in the Hypothalamic PVN: Comparison Between Sprague‐Dawley, Fisher‐344 and Lewis Rats
1994 • 147 citations
Increased striatal dopamine turnover following acute administration of rotenone to mice
2000 • 136 citations
Animal Models of PD
2002 • 133 citations
Facteurs environnementaux dans l'étiologie de la maladie de Parkinson
1990 • 121 citations
A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain
1999 • 114 citations
Synaptic stripping in the human facial nucleus
1993 • 111 citations
VI. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) in the mouse: Relationships between monoamine oxidase, MPTP metabolism and neurotoxicity
1985 • 97 citations
Contrasting Patterns and Cellular Specificity of Transcriptional Regulation of the Nuclear Receptor Nerve Growth Factor‐Inducible B by Haloperidol and Clozapine in the Rat Forebrain
2000 • 82 citations
A new link between pesticides and Parkinson's disease
2000 • 72 citations
Paraquat: A Useful Tool for the in vivo Study of Mechanisms of Neuronal Cell Death
1998 • 72 citations
The Striatum Is the Most Vulnerable Region in the Brain to Mitochondrial Energy Compromise: A Hypothesis to Explain Its Specific Vulnerability
2000 • 66 citations
Impact of antipsychotic drug administration on the expression of nuclear receptors in the neocortex and striatum of the rat brain
2001 • 60 citations
Chemical phenotype of calretinin interneurons in the human striatum
1998 • 53 citations
Mitochondrial Toxin 3-Nitropropionic Acid Induces Cardiac and Neurotoxicity Differentially in Mice
2001 • 52 citations
A Swedish county with unexpectedly high utilization of anti-Parkinsonian drugs
2009 • 41 citations
Overexpression of midbrain-specific transcription factor Nurr1 modifies susceptibility of mouse neural stem cells to neurotoxins
2002 • 40 citations
Denervation and repeated ?-DOPA induce a coordinate expression of the transcription factor NGFI-B in striatal projection pathways in hemi-parkinsonian rats
2003 • 39 citations
Environmental Exposures in Elderly Canadians With Parkinson’s Disease
1995 • 33 citations
Oral Toxicity of Rotenone to Mammals
1988 • 16 citations
Geographical variations in mortality from Parkinson's disease in Japan, 1977-1985
1995 • 13 citations
Neurotoxicity from Airborne Chemicals Around a Superfund Site
1999 • 9 citations
To the Editor
1996 • 1 citations