The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1997 • 38,984 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Automated MAD and MIR structure solution

1999 • 3,079 citations

Crystal Structure of the Ribosome at 5.5 Å Resolution

2001 • 1,905 citations

SETOR: Hardware-lighted three-dimensional solid model representations of macromolecules

1993 • 1,295 citations

Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit

2001 • 1,140 citations

ALSCRIPT: a tool to format multiple sequence alignments

1993 • 1,125 citations

Crystal Structure of the Ternary Complex of Phe-tRNA ^Phe , EF-Tu, and a GTP Analog

1995 • 846 citations

Molecular mechanisms of translation initiation in eukaryotes

2001 • 730 citations

Crystal structure of active elongation factor Tu reveals major domain rearrangements

1993 • 533 citations

Eukaryotic ribosomes require initiation factors 1 and 1A to locate initiation codons

1998 • 405 citations

Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.

1985 • 396 citations

The joining of ribosomal subunits in eukaryotes requires eIF5B

2000 • 394 citations

The Ribosome, Structure, Function, Antibiotics, and Cellular Interactions

2000 • 328 citations

A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA^Met is an important translation initiation intermediate in vivo

2000 • 283 citations

Mutations at a Zn(II) finger motif in the yeast elF-2β gene alter ribosomal start-site selection during the scanning process

1988 • 283 citations

X-Ray Structures of the Universal Translation Initiation Factor IF2/eIF5B

2000 • 238 citations

Universally conserved translation initiation factors

1998 • 237 citations

2 The Pathway and Mechanism of Eukaryotic Protein Synthesis

1996 • 225 citations

Improved high-level expression system for eukaryotic genes in Escherichia coli using T7 RNA polymerase and rare ArgtRNAs.

1995 • 219 citations

Helix unwinding in the effector region of elongation factor EF-Tu–GDP

1996 • 216 citations

GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation inSaccharomyces cerevisiae

1997 • 209 citations

The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination.

1991 • 207 citations

Reciprocal-space solvent flattening

1999 • 178 citations

Ancient Ciphers: Translation in Archaea

1997 • 159 citations

Gene‐specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2

1993 • 146 citations

Promotion of Met-tRNA _i ^Met Binding to Ribosomes by yIF2, a Bacterial IF2 Homolog in Yeast

1998 • 126 citations

Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.

2001 • 112 citations

Archaeal translation initiation revisited: The initiation factor 2 and eukaryotic initiation factor 2B α-β-δ subunit families

1998 • 103 citations

Ligand interactions with eukaryotic translation initiation factor 2: role of the gamma-subunit.

1996 • 100 citations

Universal conservation in translation initiation revealed by human and archaeal homologs of bacterial translation initiation factor IF2

1999 • 99 citations

Initiation of Protein Synthesis in Mammalian Cells with Codons Other Than AUG and Amino Acids Other Than Methionine

1998 • 94 citations

Function of Eukaryotic Translation Initiation Factor 1A (eIF1A) (Formerly Called eIF-4C) in Initiation of Protein Synthesis

1997 • 90 citations

Physical and Functional Interaction between the Eukaryotic Orthologs of Prokaryotic Translation Initiation Factors IF1 and IF2

2000 • 86 citations

The β Subunit of Eukaryotic Translation Initiation Factor 2 Binds mRNA through the Lysine Repeats and a Region Comprising the C₂-C₂ Motif

1999 • 71 citations

The C-terminal Subdomain (IF2 C-2) Contains the Entire fMet-tRNA Binding Site of Initiation Factor IF2

2000 • 65 citations

Binding of zinc to Escherichia coli phenylalanyl-tRNA synthetase. Comparison with other aminoacyl-tRNA synthetases

1981 • 64 citations

Function of eukaryotic initiation factor 5 in the formation of an 80 S ribosomal polypeptide chain initiation complex

1991 • 58 citations

Translation Initiation in Bacteria

2014 • 56 citations

Biochemical Analysis of the eIF2βγ Complex Reveals a Structural Function for eIF2α in Catalyzed Nucleotide Exchange

2001 • 53 citations

The Yeast Initiator tRNAMet can Act as an Elongator tRNAMetIn Vivo

1993 • 45 citations

The ternary complex of EF-Tu and its role in protein biosynthesis

1997 • 42 citations

Conserved sequences in the β subunit of archaeal and eukaryal translation initiation factor 2 (eIF2), absent from eIF5, mediate interaction with eIF2γ

2000 • 39 citations

Minimum Requirements for the Function of Eukaryotic Translation Initiation Factor 2

2001 • 39 citations

The A1 · U72 Base Pair Conserved in Eukaryotic Initiator tRNAs Is Important Specifically for Binding to the Eukaryotic Translation Initiation Factor eIF2

1996 • 37 citations

Isoleucyl initiator tRNA does not initiate eucaryotic protein synthesis.

1984 • 34 citations

The role of the β-subunit of initiation factor eIF-2 in initiation complex formation

1993 • 30 citations

Interaction of fMet‐tRNA^fMet and fMet‐AMP with the C‐terminal domain of Thermus thermophilus translation initiation factor 2

2000 • 29 citations

Mutation analysis of the Cys-X2-Cys-X19-Cys-X2-Cys motif in the beta subunit of eukaryotic translation initiation factor 2.

1992 • 28 citations

Functional analysis of homologs of translation initiation factor 2γ in yeast

1997 • 24 citations

Limited Proteolysis and Amino Acid Replacements in the Effector Region ofThermus thermophilusElongation Factor Tu

1996 • 20 citations

Tcl/Tk-based programs. II.CONVROT: a program to recalculate different rotation descriptions

1997 • 17 citations

The many routes of bacterial transfer RNAs after aminoacylation

2000 • 16 citations