Immune Responses to Insulin in Patients with Insulin-Dependent Diabetes Mellitus

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Type I Diabetes Mellitus

1986 • 1,615 citations

Pathologic Anatomy of the Pancreas in Juvenile Diabetes Mellitus

1965 • 1,338 citations

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

1983 • 1,078 citations

In Situ Characterization of Autoimmune Phenomena and Expression of HLA Molecules in the Pancreas in Diabetic Insulitis

1985 • 935 citations

The histopathology of the pancreas in Type I (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom

1986 • 453 citations

A SIMPLE MICRO CYTOTOXICITY TEST

1969 • 444 citations

Determinant Selection and Macrophage Function in Genetic Control of the Immune Response

1978 • 389 citations

Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.

1988 • 378 citations

Increased Circulating Ia-Antigen-Bearing T Cells in Type I Diabetes Mellitus

1982 • 227 citations

Multiple immunological abnormalities in patients with Type 1 (insulin-dependent) diabetes mellitus

1987 • 205 citations

Regulation of the Immune Response — Role of the Macrophage

1980 • 158 citations

Are Insulin Autoantibodies Markers for Insulin-Dependent Diabetes Mellitus?

1986 • 146 citations

Autoimmunity to Insulin, Beta Cell Dysfunction, and Development of Insulin-dependent Diabetes Mellitus

1986 • 137 citations

Insulin autoantibodies in the pre-diabetic period: Correlation with islet cell antibodies and development of diabetes

1986 • 124 citations

T cell autoreactivity to insulin in diabetic and related non-diabetic individuals.

1988 • 100 citations

HLA-DR 3 is associated with a more slowly progressive form of Type 1 (insulin-dependent) diabetes

1986 • 99 citations

Preventing insulin dependent diabetes mellitus: the environmental challenge. Diabetes Epidemiology Research International.

1987 • 81 citations

Anti-Insulin Antibodies in Children With Type I Diabetes Mellitus: Genetic Regulation of Production and Presence at Diagnosis Before Insulin Replacement

1986 • 68 citations

HLA Heterogeneity of Insulin-dependent Diabetes Mellitus at Diagnosis: The Pittsburgh IDDM Study

1985 • 62 citations

Cell-mediated Immunity in Diabetes Mellitus Lymphocyte Transformation by Insulin and Insulin Fragments in Insulin-treated and Newly-diagnosed Diabetics

1975 • 51 citations

Relationship between serum insulin autoantibodies, islet cell antibodies and Coxsackie-B4 and mumps virus-specific antibodies at the clinical manifestation of Type 1 (insulin-dependent) diabetes

1988 • 43 citations

Immunogenicity of monocomponent human and porcine insulin in newly diagnosed Type 1 (insulin-dependent) diabetic children

1984 • 42 citations

Culture and Phenotype of Activated T-Cells from Patients with Type I Diabetes Mellitus

1984 • 36 citations

Insulin antibodies in diabetic children treated with monocomponent porcine insulin from the onset: relationship to B-cell function and partial remission

1984 • 34 citations

Insulin autoantibodies are associated with islet cell antibodies; their relation to insulin antibodies and B-cell function in diabetic children

1988 • 28 citations

An analysis of epidemiological data in HLA-typed diabetic children

1985 • 28 citations

Recognition of human insulin in vitro by T cells from subjects treated with animal insulins.

1985 • 21 citations

HLA phenotype and insulin antibody production.

1984 • 20 citations

Cell-Mediated Immunity to Insulin and its Polypeptide Chains in Insulin-Treated Diabetics

1975 • 19 citations

The Immune Response to Insulin in Man: Interaction of HLA Alloantigens and the Development of the Immune Response

1982 • 19 citations

Insulin responses and lymphocyte subclasses in children with newly diagnosed insulin-dependent diabetes.

1988 • 18 citations

In vitro lymphocyte proliferation response to therapeutic insulin components. Evidence for genetic control by the human major histocompatibility complex.

1983 • 17 citations

Comparison of human and porcine insulin therapies in children with newly diagnosed diabetes mellitus

1987 • 17 citations

The human immune response to insulin. I. Kinetic and cellular aspects of lymphocyte proliferative responses in diabetics.

1983 • 15 citations

Proliferative responses to insulin antigens in diabetics and controls.

1983 • 11 citations

Lymphocyte proliferation as a test of the immune response to insulin in diabetics.

1985 • 7 citations

Lymphocyte transformation by insulin and insulin-zinc suspensions.

1982 • 5 citations

Characteristics of blood cells responding to insulin in children with insulin-dependent diabetes

1988 • 4 citations

Clinical and Immunologie Studies of HLA-DR Typed Insulin-Dependent Diabetics — a Mini-Review

2009 • 3 citations