Biosynthesis of ML-236B (compactin) and monacolin K.

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

1980 • 1,607 citations

ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.

1976 • 926 citations

Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.

1979 • 667 citations

Two-dimensional nuclear magnetic resonance in liquids

1982 • 405 citations

Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum

1976 • 351 citations

Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase

1985 • 285 citations

Two dimensional nuclear magnetic resonance in liquids

1983 • 254 citations

A chiral total synthesis of compactin

1982 • 108 citations

Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B)

1983 • 94 citations

Carbon-13 autocorrelation NMR using double-quantum coherence

1982 • 87 citations

Biological and pharmacological activity of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase

1981 • 56 citations

Biosynthesis of mevinolin. Spectral assignment by double-quantum coherence NMR after high carbon-13 incorporation

1983 • 56 citations

Structural modification of mevinolin

1982 • 37 citations

3.ALPHA.-Hydroxy-ML-236B(3.ALPHA.-hydroxycompactin), microbial transformation product of ML-236B (compactin)

1983 • 37 citations

Total synthesis of (+)-monacolin K (mevinolin)

1983 • 26 citations

Microbial phosphorylation of compactin (ML-236B) and related compounds.

1985 • 24 citations

6.ALPHA.-Hydroxy-iso-ML-236B (6.ALPHA.-hydroxy-iso-compactin) and ML-236A, Microbial transformation products of ML-236B.

1983 • 23 citations

Hypocholesterolemic agent compactin. an alternative diels-alder strategy for the synthesis of the hexahydronaphthalene portion

1984 • 17 citations

Specific Nonsterol Inhibitors of HMG-CoA Reductase

1985 • 12 citations