CD4+ T cells clear virus but augment disease in mice infected with respiratory syncytial virus. Comparison with the effects of CD8+ T cells

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

RESPIRATORY SYNCYTIAL VIRUS DISEASE IN INFANTS DESPITE PRIOR ADMINISTRATION OF ANTIGENIC INACTIVATED VACCINE12

1969 • 1,921 citations

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

1989 • 1,462 citations

Heterogeneity of Cytokine Secretion Patterns and Functions of Helper T Cells

1989 • 1,122 citations

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1988 • 1,086 citations

Bronchoalveolar eosinophilia during allergen-induced late asthmatic reactions.

1985 • 1,065 citations

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens.

1988 • 713 citations

FIELD EVALUATION OF A RESPIRATORY SYNCYTIAL VIRUS VACCINE AND A TRIVALENT PARAINFLUENZA VIRUS VACCINE IN A PEDIATRIC POPULATION1

1969 • 612 citations

The eosinophil and the pathophysiology of asthma

1986 • 609 citations

RESPIRATORY VIRUS IMMUNIZATION

1969 • 593 citations

Eosinophilia in transgenic mice expressing interleukin 5.

1990 • 579 citations

Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus.

1988 • 462 citations

Vaccination Against Experimental Allergic Encephalomyelitis with T Cell Receptor Peptides

1989 • 416 citations

Primary respiratory syncytial virus infection in mice

1988 • 381 citations

Recombinant human interleukin 5 is a selective eosinophil chemoattractant

1989 • 319 citations

Enhancement of respiratory syncytial virus pulmonary pathology in cotton rats by prior intramuscular inoculation of formalin-inactiva ted virus

1986 • 305 citations

Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S).

1989 • 289 citations

Study of 8-year-old children with a history of respiratory syncytial virus bronchiolitis in infancy.

1978 • 261 citations

The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent.

1988 • 261 citations

Monoclonal antibodies protect against respiratory syncytial virus infection in mice.

1984 • 240 citations

Pulmonary eosinophilic response to respiratory syncytial virus infection in mice sensitized to the major surface glycoprotein G

1992 • 228 citations

Immune and histopathological responses in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virus

1987 • 215 citations

Pulmonary Function Abnormalities in Symptom-free Children After Bronchiolitis

1977 • 192 citations

Parenteral Administration of Live Respiratory Syncytial Virus Vaccine: Results of a Field Trial

1982 • 170 citations

Clearance of persistent respiratory syncytial virus infections in immunodeficient mice following transfer of primed T cells.

1987 • 157 citations

Effectiveness of topically administered neutralizing antibodies in experimental immunotherapy of respiratory syncytial virus infection in cotton rats

1987 • 146 citations

Human cytotoxic T cells stimulated by antigen on dendritic cells recognize the N, SH, F, M, 22K, and 1b proteins of respiratory syncytial virus

1992 • 140 citations

Cooperation between cytotoxic and helper T lymphocytes in protection against lethal Sendai virus infection. Protection by T cells is MHC-restricted and MHC-regulated; a model for MHC-disease associations.

1986 • 139 citations

Administration of a highly attenuated, live respiratory syncytial virus vaccine to adults and children

1982 • 129 citations

Cell-mediated immune response to respiratory syncytial virus infection: Relationship to the development of reactive airway disease

1979 • 120 citations

The 22,000-kilodalton protein of respiratory syncytial virus is a major target for Kd-restricted cytotoxic T lymphocytes from mice primed by infection

1990 • 111 citations

Structural features of the cytoplasmic region of CD4 required for internalization.

1990 • 111 citations

Textbook of Human Virology

1992 • 100 citations

Protection against Leishmania major in BALB/c mice by adoptive transfer of a T cell clone recognizing a low molecular weight antigen released by promastigotes.

1990 • 91 citations

Viral bronchiolitis during early life induces increased numbers of bronchiolar mast cells and airway hyperresponsiveness.

1990 • 86 citations

Borna disease, a progressive meningoencephalomyelitis as a model for CD4+ T cell-mediated immunopathology in the brain.

1989 • 80 citations

Continuing respiratory problems three and a half years after acute viral bronchiolitis.

1985 • 78 citations

CD4+ suppressor cells differentially affect the production of IFN-gamma by effector cells of experimental autoimmune encephalomyelitis.

1989 • 71 citations

Analysis of the local and systemic immune responses induced in BALB/c mice by experimental respiratory syncytial virus infection

1990 • 69 citations

Flow cytometric analysis of pulmonary lymphocytes from mice infected with respiratory syncytial virus.

1989 • 54 citations

Helper T Cell Recognition of Respiratory Syncytial Virus in Mice

1988 • 50 citations

Microplaque immunoperoxidase detection of infectious respiratory syncytial virus in the lungs of infected mice

1987 • 47 citations

Importance of immunoglobulin isotype in therapy of experimental autoimmune encephalomyelitis with monoclonal anti-CD4 antibody.

1987 • 38 citations

Respiratory syncytial virus

1990 • 31 citations

Immunization of susceptible hosts with a soluble antigen fraction from Leishmania major leads to aggravation of murine leishmaniasis mediated by CD4⁺ T cells

1990 • 28 citations

Murine CD4⁺ T cell clones vary in function in vitro and in influenza infection in vivo

1990 • 24 citations

Natural Killer Cell Response to Respiratory Syncytial Virus in the Balb/C Mouse Model

1989 • 17 citations