Selection and Characterization of Human Cytochrome P450 1A2 Mutants with Altered Catalytic Properties

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 3,435 citations

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences.

1992 • 1,168 citations

The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450.

1985 • 815 citations

Reactions and significance of cytochrome P-450 enzymes

1991 • 596 citations

Principles and methods of toxicology

1995 • 407 citations

Purification and characterization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism.

1985 • 319 citations

Metabolic Activation of Aromatic Amine Mutagens by Simultaneous Expression of Human Cytochrome P450 1A2, NADPH-Cytochrome P450 Reductase, and N-Acetyltransferase in Escherichia coli

1998 • 80 citations

Role of Glu318 and Thr319 in the catalytic function of cytochrome P450 _d (P4501A2): effects of mutations on the methanol hydroxylation

1992 • 32 citations