Caveolae and transcytosis in endothelial cells: role in atherosclerosis

Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice

2001 • 1,517 citations

Transvascular delivery of small interfering RNA to the central nervous system

2007 • 1,176 citations

Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities

2001 • 1,144 citations

Identification of multiple subclasses of plasma low density lipoproteins in normal humans.

1982 • 995 citations

Subendothelial retention of atherogenic lipoproteins in early atherosclerosis

2002 • 979 citations

Albumin: Biochemical properties and therapeutic potential

2005 • 873 citations

THE FINE STRUCTURE OF THE GALL BLADDER EPITHELIUM OF THE MOUSE

1955 • 791 citations

Albumin-bound paclitaxel: a next-generation taxane

2006 • 642 citations

Caveolin-1 Regulates Transforming Growth Factor (TGF)-β/SMAD Signaling through an Interaction with the TGF-β Type I Receptor

2001 • 638 citations

A New Function for the LDL Receptor: Transcytosis of LDL across the Blood–Brain Barrier

1997 • 531 citations

Receptor-Mediated Transport of Insulin Across Endothelial Cells

1985 • 462 citations

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

2002 • 434 citations

STRUCTURAL MODULATIONS OF PLASMALEMMAL VESICLES

1968 • 427 citations

Endothelial receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties.

1989 • 383 citations

Specific binding sites for albumin restricted to plasmalemmal vesicles of continuous capillary endothelium: receptor-mediated transcytosis.

1986 • 375 citations

Gp60 Activation Mediates Albumin Transcytosis in Endothelial Cells by Tyrosine Kinase-dependent Pathway

1997 • 371 citations

Caveolin, Caveolae, and Endothelial Cell Function

2003 • 363 citations

Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels

2006 • 356 citations

Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albumin in Vivo

2001 • 325 citations

Microvascular Hyperpermeability in Caveolin-1 (−/−) Knock-out Mice

2002 • 311 citations

Pharmaceutical strategies utilizing recombinant human serum albumin.

2002 • 284 citations

Albumin-Deficient Rat Mutant

1979 • 277 citations

Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts

2003 • 229 citations

Uptake and transport of high‐density lipoprotein (HDL) and HDL‐associated α‐tocopherol by an in vitro blood–brain barrier model

2004 • 220 citations

Genetic Ablation of Caveolin-1 Confers Protection Against Atherosclerosis

2003 • 217 citations

gp60 is an albumin-binding glycoprotein expressed by continuous endothelium involved in albumin transcytosis

1992 • 210 citations

Transcytotic pathway for blood-borne protein through the blood-brain barrier.

1988 • 188 citations

Affinity-purification and characterization of caveolins from the brain: Differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types

1998 • 185 citations

Lipoprotein Trafficking in Vascular Cells

1997 • 178 citations

Open junctions in the endothelium of the postcapillary venules of the diaphragm.

1978 • 176 citations

Identification of Caveolin and Caveolin-Related Proteins in the Brain

1997 • 175 citations

shRNA and siRNA delivery to the brain

2007 • 174 citations

Transport of resveratrol, a cancer chemopreventive agent, to cellular targets: plasmatic protein binding and cell uptake

2004 • 171 citations

Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells

2006 • 161 citations

Cationic albumin conjugated pegylated nanoparticle with its transcytosis ability and little toxicity against blood–brain barrier

2005 • 154 citations

Genetic Evidence Supporting Caveolae Microdomain Regulation of Calcium Entry in Endothelial Cells

2007 • 153 citations

Transendothelial Transport: The Vesicle Controversy

2002 • 152 citations

Caveolin-1–Deficient Mice Have Increased Tumor Microvascular Permeability, Angiogenesis, and Growth

2007 • 147 citations

siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway

2005 • 142 citations

Endothelial vesicles in the blood-brain barrier: are they related to permeability?

2000 • 136 citations

Albumin, steroid hormones and the origin of vertebrates

2002 • 132 citations

Transport Across the Endothelium: Regulation of Endothelial Permeability

2006 • 122 citations

Endothelial nitric oxide synthase regulates microvascular hyperpermeability in vivo

2006 • 108 citations

Expression of caveolin-1 in human brain microvessels

2002 • 107 citations

Integrated control of lung fluid balance

2004 • 103 citations

Functional and morphological studies of protein transcytosis in continuous endothelia

2004 • 96 citations

Targeting tumor stroma and exploiting mature tumor vasculature to improve anti-cancer drug delivery

2007 • 93 citations

Caveolin-1 and caveolae in atherosclerosis: differential roles in fatty streak formation and neointimal hyperplasia

2004 • 89 citations

Transcellular transport of CCL2 across brain microvascular endothelial cells

2007 • 81 citations

Absence of albumin receptor on brain capillaries in vivo or in vitro

1985 • 78 citations

Analbuminemia: three cases resulting from different point mutations in the albumin gene.

1994 • 75 citations

Transendothelial transport (transcytosis) of iron—transferrin complex in the bone marrow

1984 • 71 citations

Caveolae and Caveolin-1: Novel Potential Targets for the Treatment of Cardiovascular Disease

2007 • 47 citations

Correlated Endothelial Caveolin Overexpression and Increased Transcytosis in Experimental Diabetes

2004 • 45 citations

Characterization of the Scavenger Receptor on Bovine Cerebral Endothelial Cells In Vitro

1993 • 32 citations

Transendothelial transport of modified low-density lipoproteins

1994 • 31 citations

Analbuminemia Produced by a Novel Splicing Mutation

2007 • 23 citations

Investigation of IgG Receptors Expressed on the Surface of Human Placental Endothelial Cells

2003 • 23 citations