The comparative effects of the NOS inhibitor, nω-nitro-l-arginine, and the haemoxygenase inhibitor, zinc protoporphyrin IX, on tumour blood flow

Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP.

1995 • 709 citations

Selective pharmacological inhibition of distinct nitric oxide synthase isoforms

1996 • 576 citations

Heme oxygenase 2: endothelial and neuronal localization and role in endothelium-dependent relaxation.

1996 • 401 citations

Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver.

1995 • 388 citations

NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium

1996 • 326 citations

Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation.

1981 • 285 citations

Induction of Heme Oxygenase-1 Expression in Vascular Smooth Muscle Cells

1997 • 192 citations

Approaches toward Selective Inhibition of Nitric Oxide Synthase

1994 • 186 citations

Pitfalls using metalloporphyrins in carbon monoxide research

1997 • 162 citations

Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo

1994 • 151 citations

Expression of Heme Oxygenase and Inducible Nitric Oxide Synthase mRNA in Human Brain Tumors

1996 • 120 citations

Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine.

1997 • 101 citations

Heme Oxygenase-2

1995 • 85 citations

Sensitivity of human tissue heme oxygenase to a new synthetic metalloporphyrin

1989 • 71 citations

Modification of Energy Metabolism and Radiation Response of a Murine Tumor by Changes in Nitric Oxide Availability

1993 • 60 citations

A Precursor of the Nitric Oxide Donor SIN-1 Modulates the Stress Protein Heme Oxygenase-1 in Rat Liver

1996 • 55 citations

Modification of tumour blood flow using the hypertensive agent, angiotensin II

1993 • 45 citations

Induction of hypoxia in experimental murine tumors by the nitric oxide synthase inhibitor, NG-nitro-L-arginine.

1994 • 43 citations

Light–dependent effects of zinc protoporphyrin IX on endothelium–dependent relaxation resistant to NoM–nitro–L–arginine

1994 • 39 citations

Nitric oxide in tumour biology and cancer therapy. Part 1: Physiological aspects

1997 • 35 citations

Characterisation of tumour blood flow using a 'tissue-isolated' preparation

1994 • 29 citations

Enhancement of heme oxygenase expression and activity in A431 squamous carcinoma multicellular tumor spheroids.

1993 • 24 citations

The Influence of Nitric Oxide on Tumour Vascular Tone

1995 • 20 citations

Modification of metabolism of transplantable and spontaneous murine tumors by the nitric oxide synthase inhibitor, nitro-L-arginine

1994 • 18 citations

Reduced capacity of tumour blood vessels to produce endothelium-derived relaxing factor: significance for blood flow modification

1996 • 17 citations