Tumor Dormancy and MYC Inactivation: Pushing Cancer to the Brink of Normalcy

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

2001 • 5,189 citations

Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome

2001 • 2,749 citations

Role of angiogenesis in tumor growth and metastasis

2002 • 2,412 citations

Role of angiogenesis in tumor growth and metastasis

2002 • 2,310 citations

Molecular themes in oncogenesis

1991 • 1,663 citations

Mechanisms of BCR–ABL in the pathogenesis of chronic myelogenous leukaemia

2005 • 1,007 citations

Essential role for oncogenic Ras in tumour maintenance

1999 • 880 citations

Reversible Tumorigenesis by MYC in Hematopoietic Lineages

1999 • 871 citations

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

2004 • 842 citations

Sustained Loss of a Neoplastic Phenotype by Brief Inactivation of MYC

2002 • 639 citations

Cancer revoked: oncogenes as therapeutic targets

2003 • 479 citations

Reprogramming of a melanoma genome by nuclear transplantation

2004 • 359 citations

Nuclear Transplantation, Embryonic Stem Cells, and the Potential for Cell Therapy

2003 • 321 citations

Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle

2004 • 270 citations

Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation

2004 • 168 citations

Nuclear cloning of embryonal carcinoma cells

2004 • 167 citations

Tumour dormancy: findings and hypotheses from clinical research on breast cancer

2001 • 148 citations

Integrin α5β1 Promotes Survival of Growth-Arrested Breast Cancer Cells

2004 • 124 citations

Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations

2003 • 117 citations

Nuclear transplantation, embryonic stem cells and the potential for cell therapy

2004 • 78 citations

T-cell immunity in the induction and maintenance of a tumour dormant state

2001 • 65 citations

Defining the temporal requirements for Myc in the progression and maintenance of skin neoplasia

2004 • 64 citations

Conditional animal models: a strategy to define when oncogenes will be effective targets to treat cancer

2004 • 56 citations

Analysis of a “phase transition” from tumor growth to latency

2000 • 56 citations

Dormancy in a model of murine B cell lymphoma

2001 • 45 citations

Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis.

2004 • 39 citations

STUDIES OF MINIMAL RESIDUAL DISEASE IN ACUTE LYMPHOCYTIC LEUKEMIA

2000 • 33 citations

Randomized controlled trial to compare the dose of adjuvant chemotherapy after curative resection of hepatocellular carcinoma

2003 • 25 citations

Advances in follicular lymphoma

2004 • 16 citations

Identification and characterisation of minimal residual disease in solid tumors.

2000 • 7 citations