The Sarco/Endoplasmic Reticulum Calcium-ATPase 2b Is an Endoplasmic Reticulum Stress-inducible Protein

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

1999 • 3,119 citations

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

1999 • 2,237 citations

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

1988 • 1,292 citations

Identification of the cis-Acting Endoplasmic Reticulum Stress Response Element Responsible for Transcriptional Induction of Mammalian Glucose-regulated Proteins

1998 • 1,216 citations

Mammalian stress response: cell physiology, structure/function of stress proteins, and implications for medicine and disease

1992 • 1,201 citations

Capacitative calcium entry

1995 • 1,112 citations

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

1998 • 888 citations

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

1998 • 782 citations

Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

1984 • 689 citations

Quality control in the secretory pathway

1995 • 679 citations

Signals from the Stressed Endoplasmic Reticulum Induce C/EBP-Homologous Protein (CHOP/GADD153)

1996 • 671 citations

How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum.

1994 • 617 citations

A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases

1998 • 580 citations

The endoplasmic reticulum Ca2+ store: a view from the lumen

1998 • 522 citations

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

1999 • 521 citations

Calcium signalling and cell proliferation

1995 • 501 citations

Golgi Tubule Traffic and the Effects of Brefeldin A Visualized in Living Cells

1997 • 469 citations

Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells

1987 • 442 citations

cDNA Cloning, functional expression, and mRNA Tissue Distribution of a Third Organellar Ca2+ Pump

1989 • 412 citations

Manipulating disulfide bond formation and protein folding in the endoplasmic reticulum.

1992 • 405 citations

Adult forms of the Ca2+ATPase of sarcoplasmic reticulum. Expression in developing skeletal muscle.

1987 • 374 citations

Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene.

1988 • 374 citations

Immunoglobulin Binding Protein (BiP) Function Is Required to Protect Cells from Endoplasmic Reticulum Stress but Is Not Required for the Secretion of Selective Proteins

1997 • 346 citations

Localization and quantification of endoplasmic reticulum Ca(2+)-ATPase isoform transcripts

1995 • 341 citations

Regulation of Translational Initiation during Cellular Responses to Stress

1997 • 280 citations

Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression

1999 • 270 citations

A novel Ca2+ pump expressed in brain, kidney, and stomach is encoded by an alternative transcript of the slow-twitch muscle sarcoplasmic reticulum Ca-ATPase gene. Identification of cDNAs encoding Ca2+ and other cation-transporting ATPases using an oligonucleotide probe derived from the ATP-binding site.

1988 • 268 citations

INTRACELLULAR SIGNALING FROM THE ENDOPLASMIC RETICULUM TO THE NUCLEUS

1998 • 258 citations

Calcium is required for folding of newly made subunits of the asialoglycoprotein receptor within the endoplasmic reticulum.

1992 • 234 citations

The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex

1999 • 231 citations

Perturbation of cellular calcium blocks exit of secretory proteins from the rough endoplasmic reticulum.

1990 • 229 citations

A sarco/endoplasmic reticulum Ca(2+)-ATPase 3-type Ca2+ pump is expressed in platelets, in lymphoid cells, and in mast cells.

1994 • 209 citations

Ca2+ Regulation of Interactions between Endoplasmic Reticulum Chaperones

1999 • 207 citations

Persistent intracellular calcium pool depletion by thapsigargin and its influence on cell growth.

1991 • 206 citations

Polarized Expression of Ca2+ Pumps in Pancreatic and Salivary Gland Cells

1997 • 184 citations

Presenilin-1 Mutation Increases Neuronal Vulnerability to Focal IschemiaIn Vivoand to Hypoxia and Glucose Deprivation in Cell Culture: Involvement of Perturbed Calcium Homeostasis

2000 • 169 citations

Palindrome with Spacer of One Nucleotide Is Characteristic of the cis-Acting Unfolded Protein Response Element inSaccharomyces cerevisiae

1998 • 146 citations

Transcriptional regulation of two genes specifically induced by glucose starvation in a hamster mutant fibroblast cell line.

1983 • 128 citations

Isoforms of endoplasmic reticulum Ca2+-ATPase are differentially expressed in normal and diabetic islets of Langerhans

1996 • 119 citations

Calcium ionophore A23187 as a regulator of gene expression in mammalian cells.

1986 • 109 citations

Generation of a Mammalian Cell Line Deficient in Glucose-regulated Protein Stress Induction through Targeted Ribozyme Driven by a Stress-inducible Promoter

1995 • 104 citations

Antibodies against the non-muscle isoform of the endoplasmic reticulum Ca2+-transport ATPase

1989 • 102 citations

Actinomycin D and 7-aminoactinomycin D binding to single-stranded DNA

1991 • 88 citations

Structure of the Human Sarco/Endoplasmic Reticulum Ca2+-ATPase 3 Gene

1998 • 85 citations

Induction of the Mammalian GRP78/BiP Gene by Ca²⁺ Depletion and Formation of Aberrant Proteins: Activation of the Conserved Stress-Inducible grp Core Promoter Element by the Human Nuclear Factor YY1

1997 • 78 citations

Co-ordinated regulation of the plasma membrane calcium pump and the sarco(endo)plasmic reticular calcium pump gene expression by Ca2+

1997 • 63 citations

Modulation of Endoplasmic Reticulum Calcium Pump Expression during T Lymphocyte Activation

1997 • 54 citations

Conservation and Divergence of the Yeast and Mammalian Unfolded Protein Response

1999 • 51 citations

Platelet Ca ²⁺ ATPases

2000 • 42 citations

Analysis of the endoplasmic reticular Ca2+ requirement for α1-antitrypsin processing and transport competence

1997 • 29 citations

Structures of the Human Gene for the Protein Disulfide Isomerase-Related Polypeptide ERp60 and a Processed Gene and Assignment of These Genes to 15q15 and 1q21

1997 • 25 citations

Thapsigargin discriminates strongly between Ca²⁺‐ATPase phosphorylated intermediates with different subcellular distributions in bovine adrenal chromaffin cells

1995 • 25 citations

Calcium Chelators and Calcium Ionophores

1988 • 6 citations