Restless Legs Syndrome

Toward a better definition of the restless legs syndrome

1995 • 1,104 citations

Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: A study of 133 patients diagnosed with new standard criteria

1997 • 924 citations

Restless legs syndrome

1960 • 856 citations

Epidemiology of Restless Legs Symptoms in Adults

2000 • 768 citations

Restless Legs Syndrome and Sleep Bruxism: Prevalence and Association Among Canadians

1994 • 718 citations

Effects of Age on Dopamine and Serotonin Receptors Measured by Positron Tomography in the Living Human Brain

1984 • 701 citations

Prevalence and risk factors of RLS in an elderly population

2000 • 661 citations

Abnormalities in CSF concentrations of ferritin and transferrin in restless legs syndrome

2000 • 598 citations

MRI measurement of brain iron in patients with restless legs syndrome

2001 • 557 citations

Iron Status and Restless Legs Syndrome in the Elderly

1994 • 487 citations

Iron and The Restless Legs Syndrome

1998 • 471 citations

Augmentation of the Restless Legs Syndrome With Carbidopa/Levodopa

1996 • 443 citations

Striatal dopaminergic function in restless legs syndrome

1999 • 419 citations

Clinical Characteristics and Frequency of the Hereditary Restless Legs Syndrome in a Population of 300 Patients

2000 • 368 citations

MR Imaging of Human Brain at 3.0 T: Preliminary Report on Transverse Relaxation Rates and Relation to Estimated Iron Content

1999 • 361 citations

Restless legs syndrome improved by pramipexole

1999 • 339 citations

The Treatment of Restless Legs Syndrome and Periodic Limb Movement Disorder

1999 • 334 citations

Restless legs syndrome

1996 • 325 citations

Reserpine and Gastric Secretion in Man

1957 • 317 citations

Restless legs syndrome in endstage renal disease

2013 • 294 citations

Successful Treatment of the Idiopathic Restless Legs Syndrome in a Randomized Double-Blind Trial of Oxycodone Versus Placebo

1993 • 288 citations

An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome

2000 • 282 citations

Circadian Rhythm of Motor Restlessness and Sensory Symptoms in the Idiopathic Restless Legs Syndrome

1999 • 270 citations

Iron Deficiency Alters Dopamine Transporter Functioning in Rat Striatum

2000 • 268 citations

Subclinical sensory neuropathy in late-onset restless legs syndrome

2000 • 262 citations

Periodic limb movements in sleep

2000 • 252 citations

Sleep in Normal Late Pregnancy

1992 • 238 citations

Treatment of restless legs syndrome and periodic movements during sleep with

1988 • 232 citations

A randomized controlled study of pergolide in patients with restless legs syndrome

1999 • 225 citations

Defining the phenotype of the restless legs syndrome (RLS) using age-of-symptom-onset

2000 • 224 citations

Immobilization tests and periodic leg movements in sleep for the diagnosis of restless leg syndrome

1998 • 224 citations

Circadian rhythm of periodic limb movements and sensory symptoms of restless legs syndrome

1999 • 218 citations

A preliminary study of the effects of correction of anemia with recombinant human erythropoietin therapy on sleep, sleep disorders, and daytime sleepiness in hemodialysis patients (The SLEEPO study)

1999 • 198 citations

Restless leg syndrome in pregnancy.

1988 • 196 citations

Determinants of nasal CPAP compliance

2002 • 195 citations

Restless legs syndrome in monozygotic twins: Clinical correlates

2000 • 193 citations

A Double-Blind, Placebo-Controlled Study of the Treatment of Periodic Limb Movements in Sleep Using Carbidopa/Levodopa and Propoxyphene

1993 • 189 citations

Therapy in Restless Legs.

1953 • 185 citations

PAINFUL LEGS AND MOVING TOES

1971 • 184 citations

Pergolide and Carbidopa/Levodopa Treatment of the Restless Legs Syndrome and Periodic Leg Movements in Sleep in a Consecutive Series of Patients

1996 • 181 citations

A double‐blind randomized crossover trial of bromocriptine and placebo in restless legs syndrome

1988 • 178 citations

Restless legs syndrome and leg cramps in fibromyalgia syndrome: a controlled study

1996 • 173 citations

Field dependent transverse relaxation rate increase may be a specific measure of tissue iron stores

1993 • 169 citations

Validation of the Johns Hopkins restless legs severity scale

2001 • 168 citations

A Randomized, Double-Blind Placebo-Controlled Trial of Iron in Restless Legs Syndrome

2000 • 163 citations

Evidence of peripheral axonal neuropathy in primary restless legs syndrome

1995 • 162 citations

Sleep-related periodic leg movements (nocturnal myoclonus) due to spinal cord lesion

1991 • 160 citations

Positron emission tomographic studies in restless legs syndrome

1999 • 160 citations

Restless legs syndrome in patients with polyneuropathy

1996 • 156 citations

Motor system excitability in patients with restless legs syndrome

1999 • 155 citations

The syndrome of painful legs and moving toes

1994 • 149 citations

Randomized, double-blind, placebo-controlled trial of pergolide in restless legs syndrome

1998 • 145 citations

Restless Legs Syndrome and Periodic Movements in Sleep

1986 • 143 citations

Clinical symptoms and possible anticipation in a large kindred of familial restless legs syndrome

1996 • 141 citations

Disturbed Sleep in Patients Complaining of Chronic Pain

1982 • 140 citations

Familial restless legs with periodic movements in sleep

1985 • 138 citations

Periodic leg movements are not more prevalent in insomnia or hypersomnia but are specifically associated with sleep disorders involving a dopaminergic impairment

2000 • 138 citations

Restless Legs Syndrome Treatment with Dopaminergic Drugs

1987 • 137 citations

NOCTURNAL MYOCLONUS

1953 • 137 citations

Noctural myoclonus syndrome (periodic movements in sleep) related to central dopamine D2-receptor alteration

1995 • 135 citations

Restless legs syndrome in 218 patients: associated disorders

2000 • 133 citations

Incidence of periodic leg movements and of the restless legs syndrome during sleep following acute physical activity in spinal cord injury subjects

1996 • 129 citations

A clinical and polysomnographic comparison of neuroleptic-induced akathisia and the idiopathic restless legs syndrome.

1991 • 125 citations

Opioid and dopamine antagonist drug challenges in untreated restless legs syndrome patients

2001 • 121 citations

Treatment of Restless Legs Syndrome with Gabapentin

1997 • 119 citations

A CLINICAL, SEROLOGICAL AND NEUROPHYSIOLOGICAL STUDY OF RESTLESS LEGS SYNDROME IN RHEUMATOID ARTHRITIS

1994 • 118 citations

Ropinirole for restless legs syndrome

1999 • 114 citations

Is Excessive Daytime Sleepiness with Periodic Leg Movements during Sleep a Specific Diagnostic Category?

1998 • 114 citations

Asthenia Crurum Paraesthetica («Irritable legs«)

1944 • 110 citations

Studies of penetrance and anticipation in five autosomal-dominant restless legs syndrome pedigrees

1999 • 110 citations

Nocturnal Myoclonus: Treatment Efficacy of Clonazepam and Temazepam

1986 • 109 citations

Charcot-Marie-Tooth disease type 2 with restless legs syndrome

1999 • 108 citations

The Treatment of the Restless Legs Syndrome with Clonazepam: A Prospective Controlled Study

1986 • 103 citations

Restless legs syndrome in the elderly

1993 • 97 citations

Bereitschaftspotential in idiopathic and symptomatic restless legs syndrome

1993 • 96 citations

Changes in excitability of motor cortical circuitry in primary restless legs syndrome

1999 • 91 citations

Pergolide in the Management of Restless Legs Syndrome: An Extended Study

1997 • 88 citations

Brain iron, transferrin and ferritin concentrations are altered in developing iron-deficient rats.

1995 • 87 citations

Effect of Pramipexole in Treatment of Resistant Restless Legs Syndrome

1998 • 85 citations

Restless leg syndrome and rheumatoid arthritis.

1986 • 83 citations

Periodic leg movements of sleep (nocturnal myoclonus): An electrophysiological study

1986 • 82 citations

Restless legs syndrome and nocturnal myoclonus: initial clinical manifestation of familial amyloid polyneuropathy.

1990 • 77 citations

Double-blind evaluation of clonazepam on periodic leg movements in sleep.

1987 • 72 citations

Symptom of Restless Legs

1965 • 71 citations

Encouraging initial response of restless legs syndrome to pramipexole

1998 • 71 citations

The influence of sex, age and sleep/wake state on characteristics of periodic leg movements in restless legs syndrome patients

1999 • 70 citations

Diurnal variation of plasma cortisol and homovanillic acid in healthy subjects

1996 • 65 citations

Reflex studies and MRI in the restless legs syndrome

1996 • 64 citations

Rapid Eye Movement Sleep Periodic Leg Movements in Patients With Spinal Cord Injury

1994 • 63 citations

Abnormal rat brain monoamine metabolism in iron deficiency anemia

1995 • 63 citations

THE SYMPTOM OF RESTLESS LEGS

1967 • 62 citations

Cryoglobulinaemic neuropathy manifesting with restless legs syndrome

1997 • 61 citations

Sleep-related periodic myoclonus in patients complaining of insomnia.

1975 • 60 citations

Restless legs syndrome in pregnancy. Case reports.

1990 • 57 citations

Clonazepam Treatment of Insomnia due to Sleep Myoclonus

1980 • 56 citations

Sensory and motor components of the restless legs syndrome

1992 • 55 citations

THE SYMPTOM OF RESTLESS LEGS

1967 • 55 citations

Periodic leg movements in sleep

1985 • 50 citations

Rheumatologic serologies in secondary restless legs syndrome

2000 • 50 citations

Treatment of periodic leg movements with a dopaminergic agonist in subjects with total spinal cord lesions

1999 • 50 citations

Restless Legs

1950 • 50 citations

The circadian variation in dopamine metabolism in the subhuman primate

1977 • 48 citations

Sleep and morning pain in primary osteoarthritis.

1987 • 47 citations

Restless Legs Syndrome, with Particular Reference to its Occurrence After Gastric Surgery

1970 • 46 citations

Blink reflex excitability is abnormal in patients with periodic leg movements in sleep

1996 • 43 citations

RESTLESS LEGS SYNDROME AFTER PARTIAL GASTRECTOMY

1966 • 39 citations

Somatosensory and Brainstem Auditory Evoked Responses in Sleep-Related Periodic Leg Movements

1986 • 38 citations

Serum‐mediated oligodendrocyte cytotoxicity in multiple sclerosis patients and controls

1986 • 20 citations