The Treatment of Restless Legs Syndrome and Periodic Limb Movement Disorder

Principles and Practice of Sleep Medicine

2011 • 5,079 citations

Drugs in Pregnancy and Lactation

1990 • 1,112 citations

Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: A study of 133 patients diagnosed with new standard criteria

1997 • 924 citations

Restless legs syndrome

1960 • 856 citations

Drugs in Pregnancy

1998 • 757 citations

Restless Legs Syndrome and Sleep Bruxism: Prevalence and Association Among Canadians

1994 • 718 citations

Iron Status and Restless Legs Syndrome in the Elderly

1994 • 487 citations

Iron and The Restless Legs Syndrome

1998 • 471 citations

Spina Bifida in Infants of Women Treated with Carbamazepine during Pregnancy

1991 • 463 citations

Augmentation of the Restless Legs Syndrome With Carbidopa/Levodopa

1996 • 443 citations

Striatal dopaminergic function in restless legs syndrome

1999 • 419 citations

Benzodiazepine Use and the Risk of Motor Vehicle Crash in the Elderly

1997 • 410 citations

Periodic movements in sleep (nocturnal myoclonus): Relation to sleep disorders

1980 • 344 citations

A questionnaire study of 138 patients with restless legs syndrome

1996 • 326 citations

Restless legs syndrome

1996 • 325 citations

Cerebral generators involved in the pathogenesis of the restless legs syndrome

1997 • 322 citations

Sleep complaints are common in a dialysis unit

1995 • 305 citations

Motor dyscontrol in narcolepsy: Rapid-eye-movement (REM) sleep without atonia and REM sleep behavior disorder

1992 • 302 citations

Restless legs syndrome in endstage renal disease

2013 • 294 citations

Periodic movements in sleep (nocturnal myoclonus) and restless legs syndrome

1982 • 290 citations

Successful Treatment of the Idiopathic Restless Legs Syndrome in a Randomized Double-Blind Trial of Oxycodone Versus Placebo

1993 • 288 citations

Long-term, nightly benzodiazepine treatment of injurious parasomnias and other disorders of disrupted nocturnal sleep in 170 adults

1996 • 286 citations

Circadian Rhythm of Motor Restlessness and Sensory Symptoms in the Idiopathic Restless Legs Syndrome

1999 • 270 citations

L-Dopa Therapy of Uremic and Idiopathic Restless Legs Syndrome: A Double-Blind, Crossover Trial

1995 • 260 citations

Treatment of restless legs syndrome and periodic movements during sleep with

1988 • 232 citations

Immobilization tests and periodic leg movements in sleep for the diagnosis of restless leg syndrome

1998 • 224 citations

Sleep Apnea and Periodic Movements in an Aging Sample

1985 • 198 citations

A Double-Blind, Placebo-Controlled Study of the Treatment of Periodic Limb Movements in Sleep Using Carbidopa/Levodopa and Propoxyphene

1993 • 189 citations

Clinical and biochemical findings in uremic patients with and without restless legs syndrome

1998 • 185 citations

Therapy in Restless Legs.

1953 • 185 citations

Pergolide and Carbidopa/Levodopa Treatment of the Restless Legs Syndrome and Periodic Leg Movements in Sleep in a Consecutive Series of Patients

1996 • 181 citations

Treatment of the restless legs syndrome with carbamazepine: a double blind study.

1984 • 179 citations

A Comparison of Reported Sleep Disorders in Patients on Chronic Hemodialysis and Continuous Peritoneal Dialysis

1992 • 178 citations

A double‐blind randomized crossover trial of bromocriptine and placebo in restless legs syndrome

1988 • 178 citations

Moderate to Severe Periodic Limb Movement Disorder in Childhood and Adolescence

1999 • 177 citations

Evidence of peripheral axonal neuropathy in primary restless legs syndrome

1995 • 162 citations

Nocturnal myoclonus and nocturnal myoclonic activity in the normal population.

1982 • 161 citations

Sleep-related periodic leg movements (nocturnal myoclonus) due to spinal cord lesion

1991 • 160 citations

Dyskinesias while awake and periodic movements in sleep in restless legs syndrome

1986 • 159 citations

Restless legs syndrome in childhood and adolescence

1994 • 159 citations

Restless Legs Syndrome and Periodic Leg Movements in Sleep: The Primary Role of Dopaminergic Mechanism

1991 • 153 citations

Nocturnal myoclonus and restless legs syndrome.

1986 • 144 citations

Restless Legs Syndrome and Periodic Movements in Sleep

1986 • 143 citations

Restless legs syndrome in uremic neuropathy

1966 • 138 citations

Restless Legs Syndrome Treatment with Dopaminergic Drugs

1987 • 137 citations

Randomized, Double-Blind, Placebo-Controlled Study of Clonidine in Restless Legs Syndrome

1996 • 132 citations

Sleep‐Wake Disorders in the Elderly: A Polysomnographic Analysis

1981 • 132 citations

Clonazepam and vibration in restless legs syndrome

1984 • 130 citations

Incidence of periodic leg movements and of the restless legs syndrome during sleep following acute physical activity in spinal cord injury subjects

1996 • 129 citations

Comparative Polysomnographic Study of Narcolepsy and Idiopathic Central Nervous System Hypersomnia

1986 • 126 citations

Dopaminergic treatment of restless legs and rebound phenomenon

1993 • 126 citations

A clinical and polysomnographic comparison of neuroleptic-induced akathisia and the idiopathic restless legs syndrome.

1991 • 125 citations

Sleep Apnea and Nocturnal Myoclonus in a Senior Population

1981 • 121 citations

Sleep‐related periodic leg movements associated with spinal cord lesions

1996 • 119 citations

Restless legs, anxiety and caffeinism.

1978 • 119 citations

Treatment of Restless Legs Syndrome with Gabapentin

1997 • 119 citations

Is Excessive Daytime Sleepiness with Periodic Leg Movements during Sleep a Specific Diagnostic Category?

1998 • 114 citations

Ropinirole for restless legs syndrome

1999 • 114 citations

Nocturnal Myoclonus: Treatment Efficacy of Clonazepam and Temazepam

1986 • 109 citations

Dopaminergic Agents in Restless Legs Syndrome and Periodic Limb Movements of Sleep: Response and Complications of Extended Treatment in 49 Cases

1993 • 108 citations

Morbidity Cut-offs for Sleep Apnea and Periodic Leg Movements in Predicting Subjective Complaints In Seniors

1990 • 107 citations

PERIODIC LIMB MOVEMENTS AND RESTLESS LEGS SYNDROME

1996 • 105 citations

The Treatment of the Restless Legs Syndrome with Clonazepam: A Prospective Controlled Study

1986 • 103 citations

Restless Legs Syndrome and Periodic Limb Movement Disorder in Children and Adolescents: Comorbidity with Attention-Deficit Hyperactivity Disorder

1996 • 102 citations

Persistence of Repetitive EEG Arousals (K-Alpha Complexes) in RLS Patients Treated With L-DOPA

1996 • 101 citations

Restless legs syndrome in the elderly

1993 • 97 citations

Restless legs and periodic leg movements in sleep syndromes

1997 • 97 citations

Bereitschaftspotential in idiopathic and symptomatic restless legs syndrome

1993 • 96 citations

L-DOPA/Carbidopa for Nocturnal Movement Disorders in Uremia

1996 • 93 citations

Occurrence of Myoclonus in Patients Treated With Cyclic Antidepressants

1987 • 92 citations

Restless Legs Syndrome

1996 • 92 citations

Pergolide in the Management of Restless Legs Syndrome: An Extended Study

1997 • 88 citations

Sleep Apnea and Sleep-related Periodic Leg Movements in Community Resident Seniors

1988 • 85 citations

Akathisia and Restless Legs

1995 • 84 citations

Dominantly inherited restless legs with myoclonus and periodic movements of sleep: a syndrome related to the endogenous opiates?

1986 • 82 citations

Periodic leg movements of sleep (nocturnal myoclonus): An electrophysiological study

1986 • 82 citations

New Actigraphic Assessment Method for Periodic Leg Movements (PLM)

1995 • 81 citations

Effect of baclofen on sleep‐related periodic leg movements

1984 • 79 citations

Pergolide: treatment of choice in restless legs syndrome (RLS) and nocturnal myoclonus syndrome (NMS). A double-blind randomized crossover trial of pergolide versus L-Dopa

1997 • 75 citations

Single photon emission tomography (SPET) imaging of dopamine D2 receptors in the course of dopamine replacement therapy in patients with nocturnal myoclonus syndrome (NMS)

1995 • 74 citations

Long-term Effect of Dopaminergic Drugs in Restless Legs

1990 • 74 citations

Double-blind evaluation of clonazepam on periodic leg movements in sleep.

1987 • 72 citations

The Effects of L-Dopa on Periodic Leg Movements and Sleep Organization in Narcolepsy

1989 • 71 citations

LEVODOPA IN RESTLESS LEGS

1986 • 71 citations

Carbamazepine in restless legs

1983 • 71 citations

Encouraging initial response of restless legs syndrome to pramipexole

1998 • 71 citations

Nocturnal myoclonus in restless legs syndrome effect of carbamazepine treatment.

1989 • 69 citations

The treatment of the restless leg syndrome with or without periodic leg movements in sleep.

1992 • 67 citations

Reflex studies and MRI in the restless legs syndrome

1996 • 64 citations

Clonazepam: effective treatment for restless legs syndrome in uraemia.

1981 • 63 citations

Restless legs syndrome and nocturnal myoclonus.

1981 • 61 citations

Narcolepsy and Disturbed Nocturnal Sleep

1983 • 59 citations

"Painful legs and moving toes" associated with polyneuropathy.

1983 • 59 citations

Response to opioids in three patients with restless legs syndrome

1984 • 57 citations

Restless legs syndrome in pregnancy. Case reports.

1990 • 57 citations

L-Dopa in Uremic Patients with the Restless Legs Syndrome

1987 • 56 citations

Clonazepam Treatment of Insomnia due to Sleep Myoclonus

1980 • 56 citations

Myoclonus in Familial Restless Legs Syndrome

1976 • 56 citations

Comparison of Cognitive-Behavioral Therapy and Clonazepam for Treating Periodic Limb Movement Disorder

1996 • 56 citations

Sensory and motor components of the restless legs syndrome

1992 • 55 citations

Treatment of restless leg syndrome with pergolide—an open clinical trial

1998 • 53 citations

Restless legs syndrome treated successfully by kidney transplantation--a case report.

1986 • 53 citations

Effects of bromocriptine on periodic limb movements in human narcolepsy

1993 • 53 citations

Opioid treatment of periodic movements in sleep in patients without restless legs

1988 • 51 citations

Periodic leg movements in sleep

1985 • 50 citations

Restless Legs Syndrome

1997 • 47 citations

Restless Legs Syndrome, with Particular Reference to its Occurrence After Gastric Surgery

1970 • 46 citations

[Restless legs syndrome and periodic movements during sleep].

1993 • 45 citations

Blink reflex excitability is abnormal in patients with periodic leg movements in sleep

1996 • 43 citations

The Effect of Sclerotherapy on Restless Legs Syndrome

1995 • 41 citations

Triazolam Diminishes Daytime Sleepiness and Sleep Fragmentation in Patients with Periodic Leg Movements in Sleep

1991 • 40 citations

Motor Functions and Dysfunctions of Sleep

2009 • 40 citations

[Successful clonidine treatment of restless leg syndrome in chronic kidney insufficiency].

1989 • 39 citations

The Use of Triazolam in Older Patients With Periodic Leg Movements, Fragmented Sleep, and Daytime Sleepiness

1990 • 38 citations

Somatosensory and Brainstem Auditory Evoked Responses in Sleep-Related Periodic Leg Movements

1986 • 38 citations

Sleep related myoclonus in rheumatic pain modulation disorder (fibrositis syndrome).

1986 • 36 citations

Thermal biofeedback and periodic movements in sleep: Patients' subjective reports and a case study

1986 • 34 citations

Folate deficiency and neurological disorders in adults

1976 • 33 citations

Nonpharmacologic treatment of periodic leg movements in sleep.

1991 • 29 citations

Opiates in the Restless Legs Syndrome

1987 • 25 citations

Assessment of the Symptomatic Benefit of Cool Dialysate

1989 • 24 citations

Peridurale Morphiumanwendung bei Restless-Legs-Status

2008 • 21 citations

Effects of Bromocriptine in Human Narcolepsy

1993 • 11 citations

Nächtliches Myoklonie-Syndrom (NMS) und Restless-Legs-Syndrom (RLS) -Übersicht und Fallbeschreibung

1994 • 9 citations

Night sleep in chronic renal insufficiency

1970 • 2 citations