Nature and nurture: overcoming constraints on immunity

γ Interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites

1987 • 699 citations

Immunology: The ins and outs of antigen processing and presentations

1986 • 498 citations

Monovalent fragments (Fab) of monoclonal antibodies to a sporozoite surface antigen (Pb44) protect mice against malarial infection.

1980 • 439 citations

SAFETY AND EFFICACY OF A RECOMBINANT DNA PLASMODIUM FALCIPARUM SPOROZOITE VACCINE

1987 • 428 citations

Rationale for Development of a Synthetic Vaccine Against Plasmodium falciparum Malaria

1985 • 371 citations

The genetics of resistance and resilience to Haemonchus contortus infection in young merino sheep

1987 • 324 citations

Nutrition, Immunity, and Infection

2010 • 306 citations

Cell-Mediated Damage to Helminths

1985 • 289 citations

The protective mucosal response against gastrointestinal nematodes in ruminants and laboratory animals

1984 • 282 citations

Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells; an in vitro assay of protective antibodies.

1984 • 280 citations

Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immunodominant T-cell domains map to the polymorphic regions of the molecule.

1988 • 264 citations

Trichinella and Trichinosis.

1983 • 261 citations

The Immune Response

1983 • 215 citations

Experimental visceral leishmaniasis: production of interleukin 2 and interferon-gamma, tissue immune reaction, and response to treatment with interleukin 2 and interferon-gamma.

1987 • 199 citations

Research Toward Malaria Vaccines

1986 • 190 citations

Genetic control of the immune response in mice to a Plasmodium falciparum sporozoite vaccine. Widespread nonresponsiveness to single malaria T epitope in highly repetitive vaccine.

1986 • 181 citations

Influence of H–2 complex on acquired resistance to Leishmania donovani infection in mice

1980 • 179 citations

Role of L3T4+ and LyT-2+ cells in experimental visceral leishmaniasis.

1988 • 162 citations

The antibody response in mice to carrier-free synthetic polymers of Plasmodium falciparum circumsporozoite repetitive epitope is I-Ab-restricted: possible implications for malaria vaccines.

1986 • 142 citations

THE REACTION OF THE HOST TO PARASITISM

1970 • 136 citations

Proteolytic cleavage of IgG bound to the Fc receptor of Schistosoma mansoni schistosomula

1981 • 135 citations

Nutrition, immunity, and infection : mechanisms of interactions

1977 • 128 citations

Genetics of Resistance to Bacterial and Parasitic Infection

1988 • 121 citations

The impact of host nutrition on gastrointestinal helminth populations

1987 • 119 citations

The effects of H-2 and non-H-2 genes on the expulsion of the nematode Trichuris muris from inbred and congenic mice

1988 • 114 citations

Immunity to Haemonchus contortus infection: relationship between age and successful vaccination with irradiated larvae.

1966 • 103 citations

Evasion of Immunity by Nematode Parasites Causing Chronic Infections

1987 • 101 citations

The T Cell Response to the Malaria Circumsporozoite Protein: An Immunological Approach to Vaccine Development

1988 • 99 citations

Cytoplasmic incompatibility in natural populations of a mosquito, Culex pipiens L.

1980 • 97 citations

I-E expression and susceptibility to parasite infection

1987 • 84 citations

Genetics of resistance to bacterial and parasitic infection

1989 • 78 citations

The response of lambs to vaccination at weaning with irradiated Trichostrongylus colubriformjs larvae: Segregation into ‘responders’ and ‘non-responders’

1978 • 76 citations

The real difficulties for malaria sporozoite vaccine development: nonresponsiveness and antigenic variation

1988 • 63 citations

Genetic control of eosinophilia. Mouse strain variation in response to antigens of parasite origin.

1983 • 62 citations

Familial predisposition to filarial infection--not linked to HLA-A or-B locus specificities.

1981 • 60 citations

The effect of sire selection on the response of lambs to vaccination with irradiated Trichostrongylus colubriformis larvae

1980 • 59 citations

Analysis of subpopulations of glass-adherent mouse skin cells controlling resistance/susceptibility to infection with Leishmania tropica, and correlation with the development of independent proliferative signals to Lyt-1+/Lyt-2+ T lymphocytes

1982 • 57 citations

Proteases secreted by transforming schistosomula of Schistosoma mansoni promote resistance to killing by complement.

1988 • 53 citations

The effect of selection of both sire and dam on the response of F1 generation lambs to vaccination with irradiated Trichostrongylus colubriformis larvae

1981 • 52 citations

Defective vaccine-induced immunity to Schistosoma mansoni in P strain mice. II. Analysis of cellular responses.

1984 • 51 citations

Genetic factors controlling the intestinal mast cell response in mice infected with Trichinella spiralis.

1982 • 50 citations

Synergism and Antagonism of Parasitic Diseases and Malnutrition

1982 • 49 citations

Host predisposition to trichuriasis: the mouse — T. muris model

1989 • 47 citations

Influence of Mouse Strain on Induction of Resistance with Irradiated Schistosoma mansoni Cercariae

1979 • 44 citations

Macrophages as effector cells of protective immunity in murine schistosomiasis. V. Variation in macrophage schistosomulacidal and tumoricidal activities among mouse strains and correlation with resistance to reinfection.

1983 • 44 citations

The response of lambs to vaccination and challenge with Trichostrongylus colubriformis: Effect of plane of nutrition on, and the inter-relationship between, immunological responsiveness and resistance

1984 • 43 citations

Transplacental transfer of rodent microfilariae induces antigen-specific tolerance in rats

1982 • 43 citations

Determinant Protection. A Hypothesis for the Activity of Immune Response Genes in the Processing and Presentation of Antigens by Macrophages

1986 • 40 citations

Host-protective immunity and its suppression in a parasitic disease: murine cutaneous leishmaniasis

1984 • 39 citations

Immunomodulation of murine visceral leishmaniasis by administration of monoclonal anti‐Ia antibodies: differential effects of anti‐I‐A vs. anti‐I‐E antibodies

1987 • 37 citations

Effect of iron and protein deficiency on the expulsion of Nippostrongylus brasiliensis from the small intestine of the rat.

1977 • 36 citations

H-2-controlled, dose-dependent suppression of the response that expels adult Trichinella spiralis from the small intestine of mice.

1984 • 36 citations

Mechanisms of protective immunity against 5. mansoni infection in mice vaccinated with irradiated cercariae. VI. Influence of the major histocompatibility complex

1984 • 33 citations

Immunological unresponsiveness to helminth parasites: I. The pattern of Nippostrongylus brasiliensis infection in young rats

1968 • 30 citations

Application of immunity in the control of parasitic disease

1980 • 28 citations

Identification of a genetic locus, Rsm-1, controlling protective immunity against Schistosoma mansoni.

1986 • 26 citations

Parasitic infection, nutrition, and immune response.

1984 • 26 citations

Studies of the responses of basophil and eosinophil leucocytes and mast cells to the nematode Trichostrongylus colubriformis: Comparison of cell populations in parasite resistant and susceptible guinea-pigs

1981 • 26 citations

Predisposition to Brugia Malayi Microfilaremia in Progeny of Infected Gerbils *

1983 • 25 citations

The influence of protein deficiency on immunity to Heligmosomoides polygyrus (Nematoda) in mice

1988 • 24 citations

Plasmodium falciparum: Sporozoite boosting of immunity due to a T-cell epitope on a sporozoite vaccine

1987 • 24 citations

Trichinella spiralis: Genetics of worm expulsion in inbred and F1 mice infected with different worm doses

1984 • 24 citations

Defective immunoglobulin M responses to vaccination or infection with Schistosoma mansoni in xid mice

1985 • 22 citations

Genetic control of immunity to Trichinella spiralis in mice. Response of rapid‐ and slow‐responder strains to immunization with parasite antigens

1986 • 20 citations

The role of T cell subpopulations in cell mediated immunity to facultative intracellular bacteria

1988 • 20 citations

Suppression of rejection of Nippostrongylus brasiliensis in iron and protein deficient rats: effect of syngeneic lymphocyte transfer.

1978 • 18 citations

Changes in the adenylate energy charge ofNippostrorigylus brasiliensisandNematodirus battusduring the development of immunity to these nematodes in their hosts

1978 • 16 citations

Effect of Schistosome-Derived Inhibitory Factor on the Cell Cycle of T Lymphocytes

1987 • 12 citations

Delayed expulsion of the nematode Nippostrongylus brasiliensis from rats on a low protein diet: the role of a bone marrow derived component

1981 • 12 citations

Regulation of cell-mediated immunity in cutaneous leishmaniasis

1987 • 9 citations

Medium Conditioned by Spleen Cells of <i>Nematospiroides dubiu</i><i>s</i>-lnfected Mice Does Not Support Development of Cultured Mast Cells

1988 • 8 citations

Prenatal sensitisation in experimental filariasis: observations on Acanthocheilonema viteae infections in mice.

1988 • 8 citations

Immunological unresponsiveness to helminth parasites

1969 • 7 citations

Genetic control of mast cell development in bone marrow cultures. Strain-dependent variation in cultures from inbred mice.

1988 • 7 citations

Parasites as immunologists

1984 • 4 citations

Schistosomes as a Potential Source of Immunopharmacological Agents

1982 • 2 citations