Rationale for Development of a Synthetic Vaccine Against Plasmodium falciparum Malaria

Human Malaria Parasites in Continuous Culture

1976 • 7,687 citations

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

1963 • 7,266 citations

Structure of the Gene Encoding the Immunodominant Surface Antigen on the Sporozoite of the Human Malaria Parasite Plasmodium falciparum

1984 • 716 citations

Immunization of man against sporozite-induced falciparum malaria

1973 • 523 citations

Separation of large denatured peptides by reverse phase high performance liquid chromatography. Trifluoroacetic acid as a peptide solvent.

1980 • 376 citations

Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes.

1983 • 311 citations

Complete in vitro maturation of Plasmodium falciparum gametocytes

1981 • 311 citations

Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells; an in vitro assay of protective antibodies.

1984 • 280 citations

tert-Butoxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin, a more acid-resistant support for solid-phase peptide synthesis

1976 • 252 citations

DNA Cloning of Plasmodium falciparum Circumsporozoite Gene: Amino Acid Sequence of Repetitive Epitope

1984 • 246 citations

Priming for and induction of anti-poliovirus neutralizing antibodies by synthetic peptides

1983 • 234 citations

Antigenic Diversity in the Human Malaria Parasite Plasmodium falciparum

1982 • 164 citations

Cloning and expression in E. coli of the malarial sporozoite surface antigen gene from Plasmodium knowlesi

1983 • 163 citations

Antibodies to Sporozoites: Their Frequent Occurrence in Individuals Living in an Area of Hyperendemic Malaria

1979 • 150 citations

Identification and chemical synthesis of a tandemly repeated immunogenic region of Plasmodium knowlesi circumsporozoite protein

1983 • 146 citations

Antibodies to the protective antigen of Plasmodium berghei sporozoites prevent entry into cultured cells.

1982 • 98 citations

Serum antibody responses of juvenile and infant rhesus monkeys injected with Haemophilus influenzae type b and pneumococcus type 6A capsular polysaccharide-protein conjugates

1984 • 92 citations

Development of sporozoite vaccines

1984 • 85 citations

Safety and immunogenicity of haemophilus influenzae type b-polysaccharide diphtheria toxoid conjugate vaccine in infants 9 to 15 months of age

1985 • 70 citations

Evidence for immunological cross-reaction between sporozoites and blood stages of a human malaria parasite

1984 • 63 citations

Circumsporozoite gene of plasmodium cynomolgi (Gombak):cDNA cloning and expression of the repetitive circumsporozoite epitope.

1984 • 61 citations

Studies in the acquisition of immunity to Plasmodium falciparum infections in Africa

1964 • 54 citations

Neutralization of the infectivity of sporozoites of Plasmodium knowlesi by antibodies to a synthetic peptide.

1984 • 49 citations

Anti-Sporozoite Antibodies Induced by Natural Infection *

1983 • 35 citations

Recent developments in the assessment of the immune response to malaria, especially as related to vaccination: Characterization of sporozoite surface antigens by indirect immunofluorescence: detection of stage- and species-specific antimalarial antibodies

1979 • 27 citations

Structure of an immunodominant epitope of the circumsporozoite surface protein of Plasmodium knowlesi

1984 • 19 citations