Methylene blue-mediated photooxidation of 7,8-dihydro-8-oxo-2′-deoxyguanosine

Oxidative stress: oxidants and antioxidants

1997 • 4,454 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

1991 • 2,172 citations

Free Radicals in Biology

1976 • 1,879 citations

The Chemical Basis of Radiation Biology

1987 • 1,843 citations

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.

1992 • 1,830 citations

The chemical basis of radiation biology

1987 • 1,788 citations

Oxidative Stress: Oxidants and Antioxidants.

1992 • 1,193 citations

Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair

1986 • 933 citations

Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

1987 • 778 citations

Endogenous mutagens and the causes of aging and cancer

1991 • 725 citations

Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome

1990 • 687 citations

Hydroxyl Free Radical Adduct of Deoxyguanosine: Sensitive Detection and Mechanisms of Formation

1986 • 660 citations

Substrate specificity of the Escherichia coli Fpg protein formamidopyrimidine-DNA glycosylase: excision of purine lesions in DNA produced by ionizing radiation or photosensitization

1992 • 597 citations

Oxygen Free Radicals Linked to Many Diseases

1987 • 399 citations

Assays for 8-hydroxy-2′-deoxyguanosine: A biomarker of in vivo oxidative DNA damage

1991 • 363 citations

2,2-Diamino-4-[(3,5-di-O-acetyl-2-deoxy-.beta.-D-erythro- pentofuranosyl)amino]-5-(2H)-oxazolone: a Novel and Predominant Radical Oxidation Product of 3',5'-Di-O-acetyl-2'-deoxyguanosine

1994 • 337 citations

On the diffusion length of singlet oxygen in cells and tissues

1990 • 326 citations

Substrate specificity of Fpg protein. Recognition and cleavage of oxidatively damaged DNA.

1994 • 321 citations

Site-specific mutagenesis using a gapped duplex vector: A study of translesion synthesis past 8-oxodeoxyguanosine in E. coli

1991 • 309 citations

Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen

1991 • 304 citations

Photosensitized formation of 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-hydroxy-2'-deoxyguanosine) in DNA by riboflavin: a nonsinglet oxygen-mediated reaction

1992 • 295 citations

Endogenous DNA adducts: Potential and paradox

1993 • 284 citations

DNA adducts, mutations and cancer

1993 • 278 citations

Role of azide in singlet oxygen reactions: Reaction of azide with singlet oxygen.

1972 • 262 citations

The photodynamic reaction of methylene blue with deoxyribonucleic acid

1962 • 230 citations

Methylene blue plus light mediates 8-hydroxyguanine formation in DNA

1989 • 229 citations

Formation of 8-hydroxyguanine moiety in deoxyribonucleic acid on .gamma.-irradiation in aqueous solution

1985 • 224 citations

Methylene blue plus light mediates 8-hydroxy 2'-deoxyguanosine formation in DNA preferentially over strand breakage

1990 • 207 citations

New trends in photobiology

1991 • 184 citations

Photosensitized reactions of nucleic acids

1986 • 180 citations

Photochemistry of intercalated methylene blue: photoinduced hydrogen atom abstraction from guanine and adenine

1993 • 175 citations

DNA damage induced by photosensitizers in cellular and cell-free systems

1993 • 167 citations

Base-specific reactions useful for DNA sequencing: methylene blue – sensitized photooxidation of guanine and osmium tetraoxide modification of thymine

1978 • 166 citations

Mechanisms and Products of Photosensitized Degradation of Nucleic Acids and Related Model Compounds

1983 • 139 citations

Methylene blue photosensitised strand cleavage of DNA: effects of dye binding and oxygen

1987 • 130 citations

Singlet oxygen-induced mutations in M13 lacZ phage DNA.

1987 • 93 citations

PHTHALOCYANINE AND NAPHTHALOCYANINE PHOTOSENSITIZED OXIDATION OF 2′‐DEOXYGUANOSINE

1992 • 93 citations

Radiation Damage in DNA: Structure/Function Relationships at Early Times

1996 • 91 citations

8-Substituted guanosine and 2'-deoxyguanosine derivatives as potential inducers of the differentiation of Friend erythroleukemia cells

1985 • 89 citations

KINETIC PROPERTIES OF THE TRIPLET STATES OF METHYLENE BLUE AND OTHER PHOTOSENSITIZING DYES

1972 • 87 citations

SINGLET OXYGEN INDUCES FRANK STRAND BREAKS AS WELL AS ALKALI‐ AND PIPERIDINE‐LABILE SITES IN SUPERCOILED PLASMID DNA

1989 • 87 citations

Photochemistry and the nucleic acids

1990 • 86 citations

Mutational specificity of oxidative DNA damage

1993 • 78 citations

TIME RESOLVED STUDIES OF 1.27 μm LUMINESCENCE FROM SINGLET OXYGEN GENERATED IN HOMOGENEOUS and MICROHETEROGENEOUS FLUIDS

1983 • 72 citations

Studies on the photosensitized breakdown of guanosine by methylene blue

1966 • 63 citations

Singlet Oxygen induced mutation spectrum in mammalian cells

1992 • 58 citations

Isolation and Characterization of a New Product Produced by Ionizing Irradiation and Type I Photosensitization of 2′-deoxyguanosine in Oxygen-saturated aqueous Solution: (2S)-2,5′-anhydro-1-(2′-deoxy-β-<scp>d</scp>-erythro-pentofuranosyl)-5-guanidinylidene-2-hydroxy-4-oxoimidazolidine

1993 • 54 citations

Photooxidation of d(TpG) by phthalocyanines and riboflavin. Isolation and characterization of dinucleoside monophosphates containing the 4R^*and 4S^*d iastereoisomers of 4,8-di hyd ro-4-hydroxy-8-oxo-2′-deoxyguanosine

1992 • 49 citations

DNA strand cleavage at 8-hydroxyguanine residues by hot piperidine treatment

1992 • 49 citations

Dna Damage by Chemically Generated Singlet Oxygen

1987 • 42 citations

PHOTOSENSITIZED OXIDATION THROUGH STEARATE MONOMOLECULAR FILMS*

1968 • 35 citations

Interaction of singlet oxygen with DNA and biological consequences

1992 • 27 citations

Base-specific photocleavage of DNA induced by nanosecond U.V. pulsed laser radiation or methylene blue sensitisation

1987 • 26 citations

The formation of one-G deletions as a consequence of singlet-oxygen-induced DNA dmage

1994 • 22 citations

Synthesis and expression of a gene coding for Erythrina trypsin inhibitor (ETI)

1994 • 21 citations

Identification of 2-deoxy-<scp>D</scp>-ribono-1,4-lactone at the site of benzophenone photosensitized release of guanine in 2′-deoxyguanosine and thymidylyl-(3′-5′)-2′-deoxyguanosine

1992 • 21 citations

Photooxydation sensibilisée de la désoxy-2’ guanosine par des phtalocyanines et naphtalocyanines. Détermination de l’importance des mécanismes de type I et de type II

1991 • 20 citations

DNA synthesis blocking lesions induced by singlet oxygen are targeted to deoxyguanosines

1992 • 20 citations

Terminations of DNA synthesis on ‘proflavine and light’-treated ØX174 single-stranded DNA

1984 • 19 citations