A lipoprotein lipase mutation (Asn291Ser) is associated with reduced HDL cholesterol levels in premature atherosclerosis

Enzymatic Determination of Total Serum Cholesterol

1974 • 9,182 citations

High density lipoprotein as a protective factor against coronary heart disease

1977 • 5,019 citations

The Metabolic Basis of Inherited Disease

1990 • 4,327 citations

Quantitative Determination of Serum Triglycerides by the Use of Enzymes

1973 • 3,206 citations

THE TROMSØHEART-STUDY

1977 • 1,212 citations

Molecular genetics of the LDL receptor gene in familial hypercholesterolemia

1992 • 1,142 citations

Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI

1991 • 990 citations

Management of patients with intramural hematoma of the thoracic aorta.

1993 • 896 citations

An efficient salt-chloroform extraction of DNA from blood and tissues.

1989 • 638 citations

Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100.

1989 • 633 citations

Familial lipoprotein disorders in patients with premature coronary artery disease.

1992 • 607 citations

Human Lipoprotein Lipase Complementary DNA Sequence

1987 • 484 citations

Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins

1989 • 468 citations

A Proposal Linking Atherogenesis to the Interaction of Endothelial Lipoprotein Lipase with Triglyceride-Rich Lipoproteins

1973 • 339 citations

Detection and characterization of the heterozygote state for lipoprotein lipase deficiency.

1989 • 295 citations

Familial lipoprotein lipase deficiency and other causes of the chylomicronemia syndrome.

1989 • 294 citations

DNA polymorphism and molecular pathology of the human globin gene clusters

1985 • 251 citations

Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium.

1993 • 238 citations

Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions.

1991 • 194 citations

Heparin--Mn2+ quantitation of high-density-lipoprotein cholesterol: an ultrafiltration procedure for lipemic samples.

1978 • 187 citations

Effect of chronic administration of propranolol on lipoprotein composition

1976 • 173 citations

Phenotypic expression of heterozygous lipoprotein lipase deficiency in the extended pedigree of a proband homozygous for a missense mutation.

1990 • 164 citations

Obesity and lipoprotein cholesterol in the Framingham offspring study

1980 • 149 citations

The novel compound NO-1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long-term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosis.

1993 • 147 citations

High density lipoprotein subfractions in relation to lipoprotein lipase activity of tissues in man—evidence for reciprocal regulation of HDL2 and HDL3 levels by lipoprotein lipase

1981 • 146 citations

Heterozygous lipoprotein lipase deficiency due to a missense mutation as the cause of impaired triglyceride tolerance with multiple lipoprotein abnormalities.

1993 • 145 citations

Lipoprotein lipase increases low density lipoprotein retention by subendothelial cell matrix.

1992 • 145 citations

Role of family history in patients with myocardial infarction. An Italian case-control study. GISSI-EFRIM Investigators.

1992 • 144 citations

Human adipose tissue lipoprotein lipase: changes with feeding and relation to postheparin plasma enzyme

1985 • 138 citations

Activities of lipoprotein lipase and hepatic triglyceride lipase in postheparin plasma of patients with low concentrations of HDL cholesterol.

1993 • 136 citations

Postheparin plasma lipoprotein and hepatic lipase are determinants of hypo- and hyperalphalipoproteinemia.

1989 • 130 citations

DNA polymorphisms at the lipoprotein lipase gene: associations in normal and hypertriglyceridaemic subjects

1989 • 127 citations

Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia.

1993 • 125 citations

DNA polymorphism haplotypes of the human lipoprotein lipase gene: possible association with high density lipoprotein levels

1991 • 121 citations

High frequency of mutations in the human lipoprotein lipase gene in pregnancy-induced chylomicronemia: possible association with apolipoprotein E2 isoform.

1994 • 116 citations

Effects of cigarette smoking on fasting triglyceride, total cholesterol, and HDL-cholesterol in women

1983 • 93 citations

Reduction of plasma high-density lipoprotein2 cholesterol and increase of postheparin plasma hepatic lipase activity during progestin treatment

1981 • 87 citations

Alteration of lipid profiles in plasma of transgenic mice expressing human lipoprotein lipase

1994 • 60 citations

Mapping of the epitope on lipoprotein lipase recognized by a monoclonal antibody (5D2) which inhibits lipase activity

1992 • 51 citations

Two naturally occurring mutations at the first and second bases of codon aspartic acid 156 in the proposed catalytic triad of human lipoprotein lipase. In vivo evidence that aspartic acid 156 is essential for catalysis.

1992 • 42 citations

The effect of propranolol treatment on total cholesterol, HDL cholesterol, triglycerides. Postheparin lipolytic activity and lecithin:cholesterol acyltransferase in hypertensive individuals.

1980 • 41 citations

Genetic and biochemical studies with ataxia telangiectasia

1981 • 25 citations

PCR assay for a polymorphicPvull site in the LPL gene

1990 • 14 citations

Ion implantation and SIMS profiling of impurities in II-VI materials (HgCdTe and CdTe)

1988 • 11 citations

Hindlll-polymorphism in the LPL-gene detected by PCR

1991 • 10 citations

Deleted Work

1955 • 0 citations