Functional Polymorphism in the Regulatory Region of Gelatinase B Gene in Relation to Severity of Coronary Atherosclerosis

A Definition of Advanced Types of Atherosclerotic Lesions and a Histological Classification of Atherosclerosis

1995 • 3,361 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes

1992 • 2,655 citations

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

1994 • 2,497 citations

The pathogenesis of coronary artery disease and the acute coronary syndromes (First of two parts)

1992 • 1,958 citations

INFLUENCE OF PLAQUE CONFIGURATION AND STRESS DISTRIBUTION ON FISSURING OF CORONARY ATHEROSCLEROTIC PLAQUES

1989 • 1,249 citations

Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage, and smooth muscle cell content.

1993 • 1,132 citations

Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture.

1995 • 723 citations

Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization.

1991 • 593 citations

A smoking–dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene

1996 • 571 citations

Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases.

1995 • 556 citations

Atherosclerotic plaque caps are locally weakened when macrophages density is increased

1991 • 541 citations

Identification of 92-kD Gelatinase in Human Coronary Atherosclerotic Lesions

1995 • 495 citations

Factors influencing the presence or absence of acute coronary artery thrombi in sudden ischaemic death

1989 • 396 citations

Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences

1996 • 351 citations

Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells.

1991 • 343 citations

Migration of cultured vascular smooth muscle cells through a basement membrane barrier requires type IV collagenase activity and is inhibited by cellular differentiation.

1994 • 318 citations

β Fibrinogen Gene Polymorphisms Are Associated With Plasma Fibrinogen and Coronary Artery Disease in Patients With Myocardial Infarction

1996 • 290 citations

Microscopic localization of active proteases by in situ zymography: detection of matrix metalloproteinase activity in vascular tissue

1995 • 277 citations

Divergent regulation by growth factors and cytokines of 95 kDa and 72 kDa gelatinases and tissue inhibitors or metalloproteinases-1, -2, and -3 in rabbit aortic smooth muscle cells

1996 • 253 citations

A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease. The ECTIM Study.

1992 • 238 citations

Epidermal growth factor and amphiregulin up‐regulate matrix metalloproteinase‐9 (MMP‐9) in human breast cancer cells

1997 • 166 citations

Acute coronary thrombosis--the role of plaque disruption and its initiation and prevention

1995 • 128 citations

Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis

1994 • 106 citations

High level expression of functional full length and truncated glucocorticoid receptor in Chinese hamster ovary cells. Demonstration of ligand-induced down-regulation of expressed receptor mRNA and protein

1991 • 99 citations

Protein-protein contacts in the glucocorticoid receptor homodimer influence its DNA binding properties.

1990 • 88 citations

Increased secretion of gelatinases A and B from the aortas of cholesterol fed rabbits: relationship to lesion severity

1997 • 46 citations