Dynamics of viral variants in HIV-1 Nef and specific cytotoxic T lymphocytes in vivo.

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

1994 • 2,529 citations

Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.

1995 • 650 citations

Adaptive Evolution of Human Immunodeficiency Virus-Type 1 During the Natural Course of Infection

1996 • 578 citations

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4.

1995 • 557 citations

Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

1994 • 545 citations

Medicine and the Law

1987 • 541 citations

AIDS virus-specific cytotoxic T lymphocytes in lung disorders

1987 • 539 citations

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

1992 • 501 citations

Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants

1994 • 418 citations

Antigenic oscillations and shifting immunodominance in HIV-1 infections

1995 • 325 citations

Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo

1984 • 296 citations

HIV-1 Reverse Transcriptase Is a Target for Cytotoxic T Lymphocytes in Infected Individuals

1988 • 270 citations

Human immunodeficiency virus type 1 Nef associateswith a cellular serine kinase in T lymphocytes.

1994 • 227 citations

Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules

1995 • 225 citations

HIV and T cell expansion in splenic white pulps is accompanied by infiltration of HIV-specific cytotoxic T lymphocytes

1994 • 209 citations

HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells.

1991 • 191 citations

Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors.

1995 • 163 citations

High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte response.

1993 • 160 citations

Cytotoxic T Lymphocyte Lysis Inhibited by Viable HIV Mutants

1995 • 107 citations

Peripheral clonal deletion of antiviral memory CD8⁺ T cells

1993 • 96 citations

In vivo persistence of a HIV‐1‐encoded HLA‐B27‐restricted cytotoxic T lymphocyte epitope despite specific in vitro reactivity

1991 • 78 citations

Effective clearance of a persistent viral infection requires cooperation between virus-specific Lyt2+ T cells and nonspecific bone marrow-derived cells

1987 • 76 citations

Cytotoxic T lymphocytes do not appear to select for mutations in an immunodominant epitope of simian immunodeficiency virus gag.

1992 • 76 citations

Peptide motifs of HLA-A3, -A24, and -B7 molecules as determined by pool sequencing

1994 • 76 citations

Immunogenic HIV variant peptides that bind to HLA-B8 can fail to stimulate cytotoxic T lymphocyte responses.

1995 • 57 citations

The Tempo and Mode of SIV Quasispecies Development in Vivo Calls for Massive Viral Replication and Clearance

1995 • 49 citations

A frameshift mutation at the NH2 terminus of the nucleoprotein gene does not affect generation of cytotoxic T lymphocyte epitopes.

1991 • 46 citations

Human Immunodeficiency Virus Reverse Transcriptase T Helper Epitopes Identified in Mice and Humans: Correlation with a Cytotoxic T Cell Epitope

1991 • 30 citations

Human immune response to HIV-1-Nef. I. CD45RO⁻ T lymphocytes of non-infected donors contain cytotoxic T lymphocyte precursors at high frequency

1994 • 20 citations

Human Immunodeficiency Virus Variants That Escape Cytotoxic T-Cell Recognition

1992 • 20 citations

Deleted Work

1955 • 0 citations