A ribonucleotide reductase gene is a transcriptional target of p53 and p73

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Requirement for p53 and p21 to Sustain G ₂ Arrest After DNA Damage

1998 • 2,784 citations

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

1999 • 2,179 citations

p63 is a p53 homologue required for limb and epidermal morphogenesis

1999 • 1,963 citations

Is a p53-Regulated Inhibitor of G2/M Progression

1997 • 1,238 citations

p21 is necessary for the p53-mediated G1 arrest in human cancer cells.

1995 • 1,193 citations

The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2

1998 • 1,152 citations

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

2000 • 979 citations

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

1999 • 914 citations

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

2000 • 877 citations

Regulation ofp53downstream genes

1998 • 777 citations

Tumor surveillance via the ARF–p53 pathway

1998 • 735 citations

Role of NF-κB in p53-mediated programmed cell death

2000 • 730 citations

Effects of p21^Cip1/Waf1 at Both the G₁/S and the G₂/M Cell Cycle Transitions: pRb Is a Critical Determinant in Blocking DNA Replication and in Preventing Endoreduplication

1998 • 714 citations

RIBONUCLEOTIDE REDUCTASES

1998 • 657 citations

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

1999 • 584 citations

Interaction of c-Abl and p73α and their collaboration to induce apoptosis

1999 • 542 citations

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.

1993 • 531 citations

Regulation of p53 stability

1999 • 413 citations

Stress Signals Utilize Multiple Pathways To Stabilize p53

2000 • 355 citations

p53 in signaling checkpoint arrest or apoptosis

1996 • 336 citations

Mechanisms of p53-mediated apoptosis

1999 • 303 citations

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant.

1996 • 299 citations

A Mutant p53 That Discriminates between p53-Responsive Genes Cannot Induce Apoptosis

1996 • 283 citations

Differential Activation of Target Cellular Promoters by p53 Mutants with Impaired Apoptotic Function

1996 • 271 citations

The role of p53 in tumour suppression: lessons from mouse models

1999 • 202 citations

New approaches to understanding p53 gene tumor mutation spectra

1999 • 199 citations

Characterization of Structural p53 Mutants Which Show Selective Defects in Apoptosis but Not Cell Cycle Arrest

1998 • 186 citations

Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression

1998 • 170 citations

Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity

1999 • 115 citations

Regulation and activation of p53 and its family members

1999 • 89 citations

The Li-Fraumeni syndrome: An inherited susceptibility to cancer

1997 • 84 citations