Transcription-dependent and transcription-independent nucleosome disruption induced by dioxin.

Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.

1976 • 1,343 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

Structure of the nucleosome core particle at 7 Å resolution

1984 • 1,028 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

Comparative Toxicology and Mechanism of Action of Polychlorinated Dibenzo-P-Dioxins and Dibenzofurans

1986 • 707 citations

Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxins and Related Products

1989 • 573 citations

Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo

1987 • 448 citations

Genetic and Molecular Aspects of 2,3,7,8-Tetra-Chlorodibenzo-P-Dioxin Action

1990 • 446 citations

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter

1990 • 440 citations

The chromatin structure of specific genes: II. Disruption of chromatin structure during gene activity

1979 • 389 citations

Role of Nucleosomal Cores and Histone H1 in Regulation of Transcription by RNA Polymerase II

1991 • 379 citations

Histone Function in Transcription

1990 • 354 citations

Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances.

1987 • 340 citations

Histone acetylation and control of gene expression

1991 • 331 citations

Specific glucocorticoid receptor binding to DNA reconstituted in a nucleosome.

1988 • 316 citations

Nucleosome Positioning: Occurrence, Mechanisms, and Functional Consequences

1991 • 248 citations

Non-random cleavage of SV40 DNA in the compact minichromosome and free in solution by micrococcal nuclease

1980 • 237 citations

TFIID binds in the minor groove of the TATA box

1991 • 206 citations

Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II

1991 • 204 citations

Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity.

1983 • 200 citations

Irresistible force meets immovable object: Transcription and the nucleosome

1991 • 175 citations

Interaction of TFIID in the minor groove of the TATA element

1991 • 170 citations

Regulation of cytochrome P1-450 gene transcription by 2,3,7, 8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells.

1984 • 166 citations

Nucleosome positioning is determined by the (H3-H4)2 tetramer.

1991 • 127 citations

Reaction of nucleosome DNA with dimethyl sulfate.

1979 • 103 citations

Mechanism of dioxin action: Ah receptor-mediated increase in promoter accessibility in vivo.

1992 • 83 citations

Isolation and characterization of a cloned DNA sequence associated with the murine Ah locus and a 3-methylcholanthrene-induced form of cytochrome P -450

1981 • 72 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible, Ah receptor-mediated bending of enhancer DNA.

1990 • 70 citations

Disruption of the typical chromatin structure in a 2500 base-pair region at the 5′ end of the actively transcribed ovalbumin gene.

1982 • 62 citations

Chromatin structure, transcription, and methylation of the prolactin gene domain in pituitary tumors of Fischer 344 rats.

1984 • 60 citations

Functional analysis of the transcriptional promoter for the CYP1A1 gene.

1990 • 58 citations

The chromatin structure of an actively expressed, single copy yeast gene

1983 • 42 citations

2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in CYP1A1 chromatin structure occurs independently of transcription.

1989 • 37 citations

Liver cells contain constitutive DNase I-hypersensitive sites at the xenobiotic response elements 1 and 2 (XRE1 and -2) of the rat cytochrome P-450IA1 gene and a constitutive, nuclear XRE-binding factor that is distinct from the dioxin receptor.

1991 • 28 citations

Functional Analysis of the Transcriptional Promoter for the CYP1A1 Gene

1990 • 11 citations

2,3,7,8-Tetrachlorodibenzo-p-Dioxin-Inducible Aryl Hydrocarbon Receptor-Mediated Change in CYP1A1 Chromatin Structure Occurs Independently of Transcription

1989 • 6 citations

Liver Cells Contain Constitutive DNase I-Hypersensitive Sites at the Xenobiotic Response Elements 1 and 2 (XRE1 and -2) of the Rat Cytochrome P-4501Al Gene and a Constitutive, Nuclear XRE- Binding Factor That Is Distinct from the Dioxin Receptor

1991 • 6 citations

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