Maintaining a defense as the injured leave the field: Apoptosis and barrier function in the intestine

Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

1998 • 2,005 citations

Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg ²⁺ Resorption

1999 • 1,107 citations

Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

1989 • 761 citations

Increased Intestinal Permeability in Patients with Crohn's Disease and Their Relatives

1986 • 731 citations

Inflammatory Bowel Disease and Adenomas in Mice Expressing a Dominant Negative N-Cadherin

1995 • 672 citations

Barrier function of epithelia

1981 • 616 citations

Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis

1999 • 587 citations

Molecular Physiology and Pathophysiology of Tight Junctions I. Tight junction structure and function: lessons from mutant animals and proteins

2000 • 439 citations

Claudins regulate the intestinal barrier in response to immune mediators

2000 • 438 citations

Extreme sensitivity of some intestinal crypt cells to X and γ irradiation

1977 • 417 citations

Tumor necrosis factor-alpha (TNFα) regulates the epithelial barrier in the human intestinal cell line HT-29/B6

1999 • 367 citations

Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro.

1995 • 337 citations

CD95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells: A possible role in ulcerative colitis

1997 • 249 citations

IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding.

1993 • 246 citations

Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: Physiological rearrangement of tight junctions

1990 • 237 citations

Importance of apoptosis in the histopathology of drug related lesions in the large intestine.

1993 • 206 citations

Epithelial cell growth and differentiation. II. Intestinal apoptosis

1997 • 190 citations

Increased small intestinal apoptosis in coeliac disease.

1996 • 159 citations

Interleukin-4 and Interleukin-13 Differentially Regulate Epithelial Chloride Secretion

1996 • 133 citations

Modulation of barrier function during Fas-mediated apoptosis in human intestinal epithelial cells

2000 • 133 citations

Fas ligand- mediated killing by intestinal intraepithelial lymphocytes. Participation in intestinal graft-versus-host disease.

1998 • 125 citations

1 Regulation of the mucosal epithelial barrier

1996 • 75 citations

Tight Junction Permeability to Ions and Water

2001 • 73 citations

Target cells for the cytotoxic effects of carcinogens in the murine small bowel

1992 • 55 citations