Origin of the beta S-globin gene in blacks: the contribution of recurrent mutation or gene conversion or both.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

1977 • 1,372 citations

Protection Afforded by Sickle-cell Trait Against Subtertian Malarial Infection

1954 • 1,228 citations

Human fetal gγ- and Aγ-globin genes: Complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes

1980 • 947 citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

1982 • 937 citations

A Specific Chemical Difference Between the Globins of Normal Human and Sickle-Cell Anæmia Hæmoglobin

1956 • 858 citations

Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

1978 • 804 citations

DNA sequence variants in the Gγ-, Aγ-, δ- and β-globin genes of man

1979 • 464 citations

Nonrandom association of polymorphic restriction sites in the β-globin gene cluster

1982 • 408 citations

The Inheritance of Sickle Cell Anemia

1949 • 343 citations

The structure of a mutant H–2 gene suggests that the generation of polymorphism in H–2 genes may occur by gene conversion-like events

1983 • 277 citations

Human beta-globin messenger RNA. III. Nucleotide sequences derived from complementary DNA.

1977 • 224 citations

Polymorphism of DNA Sequence in the β-Globin Gene Region

1980 • 213 citations

Improved Detection of the Sickle Mutation by DNA Analysis

1982 • 171 citations

Sickle-Cell Trait in Human Biological and Cultural Evolution

1967 • 161 citations

The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21→qter

1981 • 138 citations

Restriction endonuclease mapping of the human γ globin gene loci

1979 • 129 citations

Evidence for multiple origins of the beta E-globin gene in Southeast Asia.

1982 • 103 citations

Polymorphism and molecular pathology of the human beta-globin gene.

1983 • 73 citations

F-Cell Production in Sickle Cell Anemia: Regulation by Genes Linked to β-Hemoglobin Locus

1981 • 68 citations