A mutation causing pseudohypoaldosteronism type1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

1994 • 1,943 citations

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

1994 • 1,238 citations

Epithelial sodium channel related to proteins involved in neurodegeneration

1993 • 911 citations

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

1996 • 794 citations

Hypertension caused by a truncated epithelial sodium channel γ subunit: genetic heterogeneity of Liddle syndrome

1995 • 743 citations

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

1996 • 418 citations

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

1995 • 408 citations

Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans

1994 • 390 citations

Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry.

1994 • 376 citations

Membrane topology of the epithelial sodium channel in intact cells

1994 • 311 citations

The identification and suppression of inherited neurodegeneration in Caenorhabditis elegans

1990 • 304 citations

A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system.

1995 • 304 citations

Molecular Cloning and Functional Expression of a Novel Amiloride-sensitive Na+ Channel

1995 • 298 citations

Amiloride-sensitive Na channels from the apical membrane of the rat cortical collecting tubule.

1986 • 280 citations

A novel spice–site mutation in the γ subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families

1996 • 241 citations

Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel

1995 • 234 citations

A role for the beta-subunit in the expression of functional Na+-K+-ATPase in Xenopus oocytes

1989 • 228 citations

Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene.

1996 • 226 citations

Membrane topology of the amiloride-sensitive epithelial sodium channel.

1994 • 220 citations

Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel.

1994 • 219 citations

Aldosterone alters the open probability of amiloride-blockable sodium channels in A6 epithelia

1992 • 183 citations

Epithelial sodium channels

1994 • 173 citations

Cloning, expression, and tissue distribution of a human amiloride-sensitive Na+ channel

1994 • 158 citations

Gating of Na channels in the rat cortical collecting tubule: effects of voltage and membrane stretch.

1996 • 111 citations

The highly selective low-conductance epithelial Na channel of Xenopus laevis A6 kidney cells

1995 • 104 citations

Alternatively spliced forms of the alpha subunit of the epithelial sodium channel: distinct sites for amiloride binding and channel pore.

1995 • 70 citations