Endothelial Function, Nitric Oxide, and Cocoa Flavanols

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

Inflammation and Atherosclerosis

2002 • 7,456 citations

Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery

2002 • 4,535 citations

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

1999 • 3,529 citations

Paradoxical Vasoconstriction Induced by Acetylcholine in Atherosclerotic Coronary Arteries

1986 • 2,422 citations

The pathophysiology of cigarette smoking and cardiovascular disease

2004 • 2,125 citations

Close relation of endothelial function in the human coronary and peripheral circulations

1995 • 2,061 citations

Polyphenols and disease risk in epidemiologic studies

2005 • 1,907 citations

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

1995 • 1,762 citations

The clinical implications of endothelial dysfunction

2003 • 1,709 citations

Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance.

1996 • 1,695 citations

Nitric Oxide Is Responsible for Flow-Dependent Dilatation of Human Peripheral Conduit Arteries In Vivo

1995 • 1,632 citations

Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia

2004 • 937 citations

Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Blunted response in essential hypertension.

1990 • 803 citations

Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitude

2003 • 757 citations

Hyperglycemia rapidly suppresses flow-mediated endothelium- dependent vasodilation of brachial artery

1999 • 678 citations

Cholesterol Reduction in Cardiovascular Disease — Clinical Benefits and Possible Mechanisms

1995 • 676 citations

Acute Systemic Inflammation Impairs Endothelium-Dependent Dilatation in Humans

2000 • 593 citations

Nutritional, Dietary and Postprandial Oxidative Stress

2005 • 590 citations

Purple Grape Juice Improves Endothelial Function and Reduces the Susceptibility of LDL Cholesterol to Oxidation in Patients With Coronary Artery Disease

1999 • 585 citations

Impaired Progenitor Cell Activity in Age-Related Endothelial Dysfunction

2005 • 563 citations

Short- and Long-Term Black Tea Consumption Reverses Endothelial Dysfunction in Patients With Coronary Artery Disease

2001 • 540 citations

Cocoa Reduces Blood Pressure and Insulin Resistance and Improves Endothelium-Dependent Vasodilation in Hypertensives

2005 • 538 citations

Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons

2005 • 515 citations

Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans

2003 • 496 citations

Flavonoid-Rich Dark Chocolate Improves Endothelial Function and Increases Plasma Epicatechin Concentrations in Healthy Adults

2004 • 467 citations

Tetrahydrobiopterin Improves Endothelium-Dependent Vasodilation in Chronic Smokers

2000 • 448 citations

Atherosclerosis impairs flow-mediated dilation of coronary arteries in humans.

1989 • 421 citations

Long-Term Ascorbic Acid Administration Reverses Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease

1999 • 394 citations

Procyanidin Content and Variation in Some Commonly Consumed Foods

2000 • 346 citations

Acute Consumption of Flavanol-Rich Cocoa and the Reversal of Endothelial Dysfunction in Smokers

2005 • 344 citations

Hyperhomocysteinemia After an Oral Methionine Load Acutely Impairs Endothelial Function in Healthy Adults

1998 • 342 citations

Endothelium-Dependent Dilatation Is Impaired in Young Healthy Subjects With a Family History of Premature Coronary Disease

1997 • 257 citations

Plasma kinetics in man of epicatechin from black chocolate

1999 • 253 citations

Fibrinolytic Activation Markers Predict Myocardial Infarction in the Elderly

1999 • 248 citations

Evidence for in vivo transport of bioactive nitric oxide in human plasma

2002 • 226 citations

Does a glass of red wine improve endothelial function?

2000 • 207 citations

Effect of Dark Chocolate on Arterial Function in Healthy Individuals

2005 • 199 citations

Inflammation and Endothelial Function

2005 • 178 citations

Evidence for in vivo transport of bioactive nitric oxide in human plasma

2002 • 177 citations

Effects of S-nitroso-glutathione in the human forearm circulation: evidence for selective inhibition of platelet activation

1994 • 166 citations

On the Role of Vitamin C and Other Antioxidants in Atherogenesis and Vascular Dysfunction

1999 • 156 citations

Regular ingestion of black tea improves brachial artery vasodilator function

2002 • 156 citations

Plasma Nitroso Compounds Are Decreased in Patients With Endothelial Dysfunction

2006 • 118 citations

Flow-mediated dilatation in human circulation: diagnostic and therapeutic aspects

2002 • 105 citations

Effect of acetylcholine on the highly stenotic coronary artery: Difference between the constrictor response of the infarct-related coronary artery and that of the noninfarct-related artery

1992 • 89 citations

Pharmacologic versus flow-mediated assessments of peripheral vascular endothelial vasodilatory function in humans

2001 • 75 citations

Reduction of peripheral flow reserve impairs endothelial function in conduit arteries of patients with essential hypertension

2005 • 42 citations

Einfluss der Untersuchererfahrung auf intra- und interindividuelle Variabilität bei der Erfassung der peripheren Endothelfunktion mittels hochauflösendem Ultraschall

2001 • 10 citations

Selective Impairment of Nitric Oxide Dependent Vasodilation in Young Adults with Hypercholesterolemia

1996 • 8 citations