Prevention of spontaneous mammary adenocarcinoma in HER‐2/neu transgenic mice by foreign DNA

A Toll-like receptor recognizes bacterial DNA

2000 • 6,348 citations

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

CpG motifs in bacterial DNA trigger direct B-cell activation

1995 • 3,543 citations

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

1992 • 1,190 citations

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells

1998 • 809 citations

Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA.

1996 • 764 citations

CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells

1999 • 638 citations

Activation of Cutaneous Dendritic Cells by CpG-Containing Oligodeoxynucleotides: A Role for Dendritic Cells in the Augmentation of Th1 Responses by Immunostimulatory DNA

1998 • 543 citations

Toll-like Receptors and Innate Immunity

2001 • 486 citations

Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN [correction of INF] and augment IFN-mediated [correction of INF] natural killer activity.

1992 • 480 citations

CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis.

1998 • 457 citations

CpG DNA Induces Sustained IL-12 Expression In Vivo and Resistance toListeria monocytogenesChallenge

1998 • 383 citations

Cutting Edge: CpG Oligodeoxynucleotides Trigger Protective and Curative Th1 Responses in Lethal Murine Leishmaniasis

1998 • 349 citations

Bacterial DNA Containing CpG Motifs Stimulates Lymphocyte-Dependent Protection of Mice Against Lethal Infection with Intracellular Bacteria

1999 • 322 citations

Interleukin 12–mediated Prevention of Spontaneous Mammary Adenocarcinomas in Two Lines of Her-2/neu Transgenic Mice

1998 • 299 citations

Immunostimulatory DNA: Sequence‐dependent production of potentially harmful or useful cytokines

1997 • 248 citations

Modulation of amplitude and direction ofin vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens

1998 • 241 citations

HER-2/neu is a tumor rejection target in tolerized HER-2/neu transgenic mice.

2000 • 219 citations

NK- and CD8+ T Cell-Mediated Eradication of Established Tumors by Peritumoral Injection of CpG-Containing Oligodeoxynucleotides

2001 • 213 citations

Oligodeoxynucleotides containing CpG motifs can induce rejection of a neuroblastoma in mice.

1999 • 188 citations

Mitogenicity of DNA from different organisms for murine B cells.

1997 • 126 citations

Immune Recognition of Foreign DNA

1999 • 116 citations

Vaccination with the extracellular domain of p185 neu prevents mammary tumor development in neu transgenic mice

1999 • 84 citations

Antisense c-myc and Immunostimulatory Oligonucleotide Inhibition of Tumorigenesis in a Murine B-Cell Lymphoma Transplant Model

1998 • 79 citations

Genetic immunization against neu /erbB2 transgenic breast cancer

1998 • 78 citations

Prevention of spontaneous neu-expressing mammary tumor development in mice transgenic for rat proto-neu by DNA vaccination

2001 • 67 citations

Antimetastatic effect of CpG DNA mediated by type I IFN.

2001 • 64 citations

Tamoxifen chemoprevention of a hormone-independent tumor in the proto-neu transgenic mice model.

2000 • 50 citations

Inhibition of mammary carcinogenesis by systemic interleukin 12 or p185neu DNA vaccination in Her-2/neu transgenic BALB/c mice.

2001 • 41 citations

Absence of the CD1 Molecule Up-Regulates Antitumor Activity Induced by CpG Oligodeoxynucleotides in Mice

2002 • 31 citations

Antisense c-mycInhibition of Lymphoma Growth

1997 • 18 citations

Cooperative effects of Mycobacterium tuberculosis Ag38 gene transduction and interleukin 12 in vaccination against spontaneous tumor development in proto-neu transgenic mice.

2000 • 9 citations

Anti-tumor immunity induced by murine melanoma cells transduced with the Mycobacterium tuberculosis gene encoding the 38-kDa antigen

1998 • 7 citations