DNA bending is induced in an enhancer by the DNA-binding domain of the bovine papillomavirus E2 protein.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

1986 • 626 citations

Improved oligonudeotide site-directed rautagenesis using M13 vectors

1985 • 545 citations

Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

1987 • 512 citations

Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product

1985 • 402 citations

Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences.

1981 • 387 citations

The primary structure and genetic organization of the bovine papillomavirus type 1 genome

1982 • 374 citations

Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA

1987 • 330 citations

In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA

1980 • 288 citations

A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator

1987 • 278 citations

Glucocorticoid Receptor Mutants That Define a Small Region Sufficient for Enhancer Activation

1987 • 260 citations

Binding of a simian virus 40 T antigen-related protein to DNA

1981 • 233 citations

The integration host factor of Escherichia coli binds to bent DNA at the origin of replication of the plasmid pSC101

1987 • 228 citations

An altered DNA conformation in origin region I is a determinant for the binding of SV40 large T antigen

1986 • 200 citations

Bovine papillomavirus transcriptional regulation: localization of the E2-responsive elements of the long control region

1987 • 160 citations

Rapid purification of a cloned gene product by genetic fusion and site-specific proteolysis.

1984 • 159 citations

Messenger RNAs from the transforming region of bovine papilloma virus type I

1985 • 120 citations

Association of DNA-bound progesterone receptors

1987 • 116 citations

Bending of promoter DNA on binding of heat shock transcription factor

1986 • 101 citations

The E2 "gene" of bovine papillomavirus encodes an enhancer-binding protein.

1987 • 98 citations

The replication initiator protein of plasmid R6K tagged with β-galactosidase shows sequence-specific DNA-binding

1983 • 73 citations

Why should DNA loop?

1987 • 57 citations

DNA-binding activity of papillomavirus proteins

1987 • 51 citations

Purification of E. coli enzymes by chromatography on amphiphilic gels

1975 • 31 citations