Role of the liver-enriched transcription factors C/EBPα and DBP in the expression of human CYP3A4 and CYP3A7

Gene regulation by steroid hormones

1989 • 3,466 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature

1993 • 1,663 citations

The Liver: Biology and Pathobiology.

1983 • 1,628 citations

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

1992 • 1,156 citations

A novel cationic liposome reagent for efficient transfection of mammalian cells

1991 • 844 citations

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 • 641 citations

A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

1991 • 604 citations

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes.

1992 • 536 citations

Molecular genetics of the P-450 superfamily

1990 • 496 citations

CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells.

1989 • 488 citations

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues.

1990 • 487 citations

Differential expression of sucrase-isomaltase in clones isolated from early and late passages of the cell line caco-2: Evidence for glucose-dependent negative regulation

1994 • 416 citations

DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally

1990 • 410 citations

The Liver: Biology and Pathology

1989 • 348 citations

Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver

1994 • 269 citations

Gene structure of CYP3A4, an adult‐specific form of cytochrome P450 in human livers, and its transcriptional control

1993 • 208 citations

Fetus-specific expression of a form of cytochrome P-450 in human livers

1990 • 205 citations

Growth-dependent inhibition of CCAAT enhancer-binding protein (C/EBP alpha) gene expression during hepatocyte proliferation in the regenerating liver and in culture.

1992 • 151 citations

Temporal expression of the human alcohol dehydrogenase gene family during liver development correlates with differential promoter activation by hepatocyte nuclear factor 1, CCAAT/enhancer-binding protein alpha, liver activator protein, and D-element-binding protein.

1992 • 83 citations

Oxidative metabolism of lansoprazole by human liver cytochromes P450.

1995 • 77 citations

Sequence of the 5′-Flanking Region of CYP3A5: Comparative Analysis with CYP3A4 and CYP3A7

1994 • 54 citations

Genomic organization of human fetal specific P-450IIIA7(cytochrome P-450HFLa)-related gene(s) and interaction of transcriptional regulatory factor with its DNA element in the 5′ flanking region

1992 • 50 citations

Regulation of two rat serine‐protease inhibitor gene promoters by somatotropin and glucocorticoids

1992 • 38 citations

A gene structure of testosterone 6β-hydroxylase (P450IIIA)

1991 • 18 citations

Electrotransfer of Microsomal Cytochrome P450 After Isoelectric Focusing (IEF Blots): Resolution of Human 2A and 3A Isozymes

1994 • 6 citations

Deleted Work

1955 • 0 citations