Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å

1991 • 2,034 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

1990 • 577 citations

GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families

1991 • 549 citations

Cloning, Expression, and Gene Structure of a G Protein-Coupled Glutamate Receptor from Rat Brain

1991 • 524 citations

A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene

1986 • 409 citations

Structural homology of the product of the Drosophila Krüppel gene with Xenopus transcription factor IIIA

1986 • 406 citations

Finger protein of novel structure encoded by hunchback, a second member of the gap class of Drosophila segmentation genes

1987 • 370 citations

Tetracycline-Reversible Silencing of Eukaryotic Promoters

1995 • 271 citations

Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts

1985 • 229 citations

GAL4 fusion vectors for expression in yeast or mammalian cells

1992 • 213 citations

A multigene family encoding several “finger” structures is present and differentially active in mammalian genomes

1987 • 197 citations

The Human Genome Contains Hundreds of Genes Coding for Finger Proteins of the Krüppel Type

1989 • 184 citations

Repression of transcriptional activity at a distance by the evolutionary conserved KRAB domain present in a subfamily of zinc finger proteins

1994 • 132 citations

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

1993 • 130 citations

Isolation and Fine Mapping of 16 Novel Human Zinc Finger-Encoding cDNAs Identify Putative Candidate Genes for Developmental and Malignant Disorders

1995 • 123 citations

Members of the zinc finger protein gene family sharing a conserved N-terminal module

1991 • 80 citations

Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.

1991 • 75 citations

A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome

1993 • 48 citations

The finger motif defines a multigene family represented in the maternal mRNA of Xenopus laevis oocytes.

1988 • 45 citations

Clustering of C2H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes

1992 • 41 citations

Conserved KRAB protein domain identified upstream from the zinc finger region of Kox 8

1991 • 36 citations

A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10

1992 • 29 citations

The identification and characterization of KRAB-domain-containing zinc finger proteins

1992 • 21 citations

Determination of DNA binding specificities of mutated zinc finger domains

1991 • 17 citations