Prognostic significance of cyclin E and p53 protein overexpression in carcinoma of the renal pelvis and ureter

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1989 • 920 citations

Identification of p53 Gene Mutations in Bladder Cancers and Urine Samples

1991 • 891 citations

Induction of WAF1/CIP1 by a p53-independent pathway.

1994 • 773 citations

Cyclins and cancer

1991 • 701 citations

Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining.

1994 • 673 citations

A p53-Dependent Mouse Spindle Checkpoint

1995 • 668 citations

Expression and amplification of cyclin genes in human breast cancer.

1993 • 667 citations

Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia.

1995 • 549 citations

Redundant cyclin overexpression and gene amplification in breast cancer cells.

1993 • 526 citations

Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53.

1994 • 514 citations

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

1991 • 475 citations

Alternate splicing produces a novel cyclin D1 transcript.

1995 • 406 citations

Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck.

1995 • 368 citations

Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer.

1993 • 367 citations

Cyclin E, a Potential Prognostic Marker in Breast Cancer.

1997 • 346 citations

Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

1992 • 331 citations

A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1.

1991 • 265 citations

PRAD-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas.

1994 • 263 citations

Deregulation of cyclin E in breast cancer.

1995 • 227 citations

Amplification of cyclin genes in colorectal carcinomas.

1993 • 197 citations

Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways.

1994 • 196 citations

Cyclin gene amplification and overexpression in breast and ovarian cancers: Evidence for the selection ofcyclin D1 in breast andcyclin E in ovarian tumors

1996 • 180 citations

Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines.

1994 • 124 citations

p21WAF1 immunohistochemical expression in breast carcinoma: correlations with clinicopathological data, oestrogen receptor status, MIB1 expression, p53 gene and protein alterations and relapse-free survival

1996 • 121 citations

High-risk human papillomavirus infections and overexpression of p53 protein as prognostic indicators in transitional cell carcinoma of the urinary bladder.

1993 • 90 citations

Relationship between p21 expression and mutation of the p53 tumor suppressor gene in normal and malignant ovarian epithelial cells.

1996 • 78 citations

Expression of cyclin E in colorectal adenomas and adenocarcinomas: correlation with expression of Ki-67 antigen and p53 protein

1996 • 63 citations

Cyclin D1 overexpression related to retinoblastoma protein expression as a prognostic marker in human oesophageal squamous cell carcinoma

1998 • 62 citations

Genetic Status and Expression of the Cyclin‐dependent Kinase Inhibitors in Human Gastric Carcinoma Cell Lines

1996 • 47 citations

Histopathological Features and p53 Nuclear Protein Staining as Predictors of Survival and Tumor Recurrence in Patients with Transitional Cell Carcinoma of Renal Pelvis

1995 • 36 citations

DETECTION OF p53 AND bcl-2 PROTEIN IN CARCINOMA OF THE RENAL PELVIS AND URETER INCLUDING DYSPLASIA

1996 • 32 citations

THE ABERRANT P53 PROTEIN (REVIEW)

1995 • 25 citations

p53 and human papillomavirus dna in renal pelvic and ureteral carcinoma including dysplastic lesions

1995 • 17 citations