Cyclin D1 overexpression related to retinoblastoma protein expression as a prognostic marker in human oesophageal squamous cell carcinoma

Cyclins and cancer II: Cyclin D and CDK inhibitors come of age

1994 • 2,122 citations

Mammalian G1 cyclins

1993 • 1,990 citations

Tumor Suppressor Genes

1991 • 1,784 citations

Cyclin A is required at two points in the human cell cycle.

1992 • 1,380 citations

A novel cyclin encoded by a bcl1-linked candidate oncogene

1991 • 1,286 citations

D-type cyclin-dependent kinase activity in mammalian cells.

1994 • 1,073 citations

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

1993 • 1,047 citations

Cyclins and cancer

1991 • 701 citations

Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining.

1994 • 673 citations

Expression and amplification of cyclin genes in human breast cancer.

1993 • 667 citations

Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia.

1995 • 549 citations

Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck.

1995 • 368 citations

Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer.

1993 • 367 citations

Cyclin E, a Potential Prognostic Marker in Breast Cancer.

1997 • 346 citations

D-Type Cyclin-Dependent Kinase Activity in Mammalian Cells

1994 • 322 citations

PRAD-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas.

1994 • 263 citations

Amplification and Overexpression of Cyclin D1 in Human Hepatocellular Carcinoma

1993 • 237 citations

Cyclin D1 expression is regulated by the retinoblastoma protein.

1994 • 235 citations

Determination of the prognostic value of cyclin D1 overexpression in breast cancer.

1995 • 215 citations

Overexpression and localization of cyclin D1 mRNA and antigen in esophageal cancer.

1995 • 142 citations

Cyclin D1 amplification as a new predictive classification for squamous cell carcinoma of the esophagus, adding gene information.

1996 • 124 citations

Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines.

1994 • 124 citations

The retinoblastoma susceptibility gene product: a characteristic pattern in normal cells and abnormal expression in malignant cells.

1989 • 104 citations

Prognostic significance of human papillomavirus genomes (type‐16, ‐18) and aberrant expression of p53 protein in human esophageal cancer

1993 • 104 citations

Oesophageal cancer and amplification of the human cyclin D gene CCND1/PRAD1

1995 • 102 citations

Antibodies detecting abnormalities of the retinoblastoma susceptibility gene product (pp110RB) in osteosarcomas and synovial sarcomas.

1989 • 88 citations

Lymph node metastasis in thoracic esophageal carcinoma

1991 • 88 citations

Lack of nuclear RB protein staining in G0/middle G1 cells: correlation to changes in total RB protein level.

1991 • 88 citations

Significance of p53 expression as a prognostic factor in oesophageal squamous cell carcinoma

1993 • 82 citations

Aberrant RB gene expression in routinely processed, archival tumor tissues determined by three different anti‐RB antibodies

1994 • 66 citations

Evaluation of the new (1987) TNM classification for thoracic esophageal tumors

1993 • 62 citations

Retinoblastoma and p53 gene product expression in breast carcinoma: Immunohistochemical analysis and clinicopathologic correlation

1992 • 59 citations

Determination of the prognostic significance of unscheduled cyclin A overexpression in patients with esophageal squamous cell carcinoma.

1996 • 57 citations

Amplification and Overexpression of EXP1 and EXP2/Cyclin D1 Genes in Human Esophageal Carcinomas

1993 • 45 citations

Tumor recurrence in long-term survivors after treatment of carcinoma of the esophagus

1994 • 44 citations

Reduced expression of retinoblastoma (Rb) gene protein is related to cell proliferation and prognosis in transitional-cell bladder cancer

1995 • 38 citations

Tumor suppressor genes

1991 • 28 citations