Alteration in mucin gene expression and biological properties of HT29 colon cancer cell subpopulations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

1990 • 994 citations

Human Tumor Cells in Vitro

1975 • 753 citations

Heterogeneity of mucin gene expression in normal and neoplastic tissues.

1993 • 671 citations

Identification of the gastrointestinal and pancreatic cancer-associated antigen detected by monoclonal antibody 19-9 in the sera of patients as a mucin.

1983 • 591 citations

Physiology of the Digestive Tract.

1961 • 587 citations

Molecular Cloning of Human Intestinal Mucin cDNAs

1989 • 544 citations

Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7).

1993 • 461 citations

Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization.

1993 • 455 citations

Cloning and sequencing of a human pancreatic tumor mucin cDNA.

1990 • 435 citations

Growth adaptation to methotrexate of HT-29 human colon carcinoma cells is associated with their ability to differentiate into columnar absorptive and mucus-secreting cells.

1990 • 414 citations

Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs

1991 • 405 citations

Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients

1990 • 380 citations

Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini.

1990 • 376 citations

Human gastric mucin. Identification of a unique species by expression cloning.

1993 • 370 citations

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene

1990 • 367 citations

Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen.

1988 • 310 citations

Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer

1994 • 284 citations

Mucins in the human gastrointestinal epithelium: a review.

1979 • 267 citations

Differential expression of the human mucin genes MUC1 to MUC5 in relation to growth and differentiation of different mucus-secreting HT-29 cell subpopulations

1993 • 258 citations

Human epithelial tumor antigen cDNA sequences

1990 • 242 citations

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

1994 • 222 citations

Polyamines Differentially Modulate the Transcription of Growth-associated Genes in Human Colon Carcinoma Cells

1989 • 211 citations

Mucins: structure, function, and role in pulmonary diseases

1992 • 205 citations

Physiology of the Digestive Tract.

1971 • 195 citations

Oligosaccharide structures of isolated human colonic mucin species.

1985 • 174 citations

Altered expression of MUC2, MUC4, and MUC5 mucin genes in pancreas tissues and cancer cell lines

1994 • 171 citations

Cell surface sialylation and tumor metastasis. Metastatic potential of B16 melanoma variants correlates with their relative numbers of specific penultimate oligosaccharide structures.

1988 • 148 citations

Mucin gene expression in colonic tissues and cell lines.

1992 • 144 citations

Tumor cell surface carbohydrate and the metastatic phenotype

1987 • 144 citations

A novel human airway mucin cDNA encodes a protein with unique tandem-repeat organization

1994 • 130 citations

Tumor Cell Adhesion to Endothelial Cells: Endothelial Leukocyte Adhesion Molecule-1 as an Inducible Adhesive Receptor Specific for Colon Carcinoma Cells

1991 • 129 citations

Porcine submaxillary gland apomucin contains tandemly repeated, identical sequences of 81 residues.

1988 • 127 citations

Sialyl-dimeric Lewis-X antigen expressed on mucin-like glycoproteins in colorectal cancer metastases.

1990 • 124 citations

Evidence for Different Human Tracheobronchial Mucin Peptides Deduced from Nucleotide cDNA Sequences

1991 • 122 citations

Inhibition of selectin-dependent tumor cell adhesion to endothelial cells and platelets by blocking O-glycosylation of these cells

1992 • 122 citations

A new animal model for human colon cancer metastasis

1987 • 117 citations

Cell surface sialoprotein alterations in metastatic murine colon cancer cell lines selected in an animal model for colon cancer metastasis.

1990 • 97 citations

Monoclonal antibodies against oncofetal mucin M1 antigens associated with precancerous colonic mucosae.

1986 • 97 citations

Colorectal cancer metastasis determined by carbohydrate-mediated cell adhesion: role of sialyl-LeX antigens.

1993 • 90 citations

Dihydrofolate reductase gene amplification-associated shift of differentiation in methotrexate-adapted HT-29 cells.

1991 • 89 citations

Oligosaccharide structures of mucins secreted by the human colonic cancer cell line CL.16E.

1992 • 75 citations

Mucin synthesis and secretion in relation to spontaneous differentiation of colon cancer cells in vitro

1992 • 69 citations

Relationship of pancreatic cancer apomucin to mammary and intestinal apomucins.

1991 • 40 citations

Expression and characterization of mucins associated with the resistance to methotrexate of human colonic adenocarcinoma cell line HT29.

1992 • 39 citations

The Structure of Human Intestinal Apomucins

1991 • 38 citations

Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells

1992 • 38 citations

Characteristics of colorectal carcinoma cells with high metastatic potential

1984 • 35 citations

Monoclonal antibodies against partially deglycosylated colon cancer mucin that recognize Tn antigen.

1992 • 34 citations

Expression of native and deglycosylated colon cancer mucin antigens in normal and malignant epithelial tissues.

1990 • 29 citations

Monoclonal antibody directed against colon cancer mucin has high specificity for malignancy

1993 • 18 citations