Differential expression of the human mucin genes MUC1 to MUC5 in relation to growth and differentiation of different mucus-secreting HT-29 cell subpopulations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Basic Methods in Molecular Biology

1986 • 3,284 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

1990 • 994 citations

New Human Tumor Cell Lines

1975 • 974 citations

Heterogeneity of mucin gene expression in normal and neoplastic tissues.

1993 • 671 citations

A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats.

1988 • 571 citations

Molecular Cloning of Human Intestinal Mucin cDNAs

1989 • 544 citations

Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate.

1984 • 532 citations

Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells.

1985 • 497 citations

Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization.

1993 • 455 citations

Cloning and sequencing of a human pancreatic tumor mucin cDNA.

1990 • 435 citations

Growth adaptation to methotrexate of HT-29 human colon carcinoma cells is associated with their ability to differentiate into columnar absorptive and mucus-secreting cells.

1990 • 414 citations

Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs

1991 • 405 citations

Human gastric mucin. Identification of a unique species by expression cloning.

1993 • 370 citations

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene

1990 • 367 citations

Absorptive and mucus-secreting subclones isolated from a multipotent intestinal cell line (HT-29) provide new models for cell polarity and terminal differentiation.

1987 • 343 citations

A monoclonal antibody (B72.3) defines patterns of distribution of a novel tumor‐associated antigen in human mammary carcinoma cell populations

1982 • 324 citations

Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epithelium.

1987 • 288 citations

The human tumour-associated epithelial mucins are coded by an expressed hypervariable gene locus PUM

1987 • 281 citations

The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region.

1992 • 270 citations

Oligosaccharide structures of human colonic mucin.

1985 • 253 citations

Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells?

1985 • 193 citations

MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphism.

1991 • 187 citations

Oligosaccharide structures of isolated human colonic mucin species.

1985 • 174 citations

Cl- secretion in epithelial monolayers of mucus-forming human colon cells (HT-29/B6)

1991 • 173 citations

Mucin gene expression in colonic tissues and cell lines.

1992 • 144 citations

Degenerate 87-base-pair tandem repeats create hydrophilic/hydrophobic alternating domains in human mucin peptides mapped to 11p15

1993 • 133 citations

Immunoglobulin G3 monoclonal antibody directed to Tn antigen (tumor-associated alpha-N-acetylgalactosaminyl epitope) that does not cross-react with blood group A antigen.

1988 • 130 citations

Evidence for Different Human Tracheobronchial Mucin Peptides Deduced from Nucleotide cDNA Sequences

1991 • 122 citations

High-molecular-weight glycoproteins of human teratocarcinoma defined by monoclonal antibodies to carbohydrate determinants.

1985 • 109 citations

Human intestinal goblet cells in monolayer culture: Characterization of a mucus-secreting subclone derived from the HT29 colon adenocarcinoma cell line

1988 • 98 citations

Monoclonal antibodies against oncofetal mucin M1 antigens associated with precancerous colonic mucosae.

1986 • 97 citations

Human bronchus and intestine express the same mucin gene.

1991 • 94 citations

Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation.

1990 • 91 citations

Dihydrofolate reductase gene amplification-associated shift of differentiation in methotrexate-adapted HT-29 cells.

1991 • 89 citations

Neutral and acidic species of human intestinal mucin. Evidence for different core peptides.

1985 • 88 citations

Adaptation to 5‐fluorouracil of the heterogeneous human colon tumor cell line ht‐29 results in the selection of cells committed to differentiation

1991 • 81 citations

Oligosaccharide structures of mucins secreted by the human colonic cancer cell line CL.16E.

1992 • 75 citations

Detection of the MUC2 apomucin tandem repeat with a mouse monoclonal antibody

1993 • 74 citations

Assignment of the polymorphic intestinal mucin gene (MUC2) to chromosome 11p15

1990 • 74 citations

Differential mucin gene expression in human pancreatic and colon cancer cells

1991 • 70 citations

cis-Golgi resident proteins and O-glycans are abnormally compartmentalized in the RER of colon cancer cells

1993 • 70 citations

Increased growth adaptability to 5‐fluorouracil and methotrexate of HT‐29 sub‐populations selected for their commitment to differentiation

1991 • 69 citations

Human colonic goblet cells. Demonstration of distinct subpopulations defined by mucin-specific monoclonal antibodies.

1986 • 67 citations

The core polypeptide of cystic fibrosis tracheal mucin contains a tandem repeat structure. Evidence for a common mucin in airway and gastrointestinal tissue.

1990 • 64 citations

Assignment of human tracheobronchial mucin gene(s) to 11p15 and a tracheobronchial mucin-related sequence to chromosome 13

1990 • 59 citations

ABO ANTIBODIES—SEROLOGICAL BEHAVIOUR AND IMMUNO‐CHEMICAL CHARACTERIZATION

1990 • 54 citations

Reactivity of anti-human milk fat globule antibodies with synthetic peptides.

1989 • 51 citations

Diversity of the peptide moiety of human airway mucins

1990 • 49 citations

Monoclonal antibodies recognizing epitopes carried on both glycolipids and glycoproteins of the human milk fat globule membrane

1985 • 48 citations

Production of MUC1 and MUC2 mucins by human tumor cell lines

1991 • 42 citations

Regional localization of the intestinal mucin gene MUC3 to chromosome 7q22

1992 • 39 citations

Expression and characterization of mucins associated with the resistance to methotrexate of human colonic adenocarcinoma cell line HT29.

1992 • 39 citations

Mucin 4 (MUC4) gene: regional assignment (3q29) and RFLP analysis.

1992 • 38 citations

Ectopic expression of the Y (Le^y) antigen defined by monoclonal antibody 12‐4LE in distal colonic adenocarcinomas

1988 • 27 citations

Dipeptidyl peptidase IV expression in rat jejunal crypt-villus axis is controlled at mRNA level

1991 • 24 citations

Asymmetrical distribution of epithelial membrane antigen on the plasma membranes of human breast cell lines in culture.

1981 • 20 citations

Secretory epithelial cell marker on gastrointestinal tumors and in human secretions defined by a monoclonal antibody.

1987 • 16 citations

Ultrastructural localization of milk fat globule membrane antigens in human breast carcinomas

1990 • 10 citations

Immunohistological patterns of 20 monoclonal antibodies against non-A non-B glycoconjugates in normal human pyloric and duodenal mucosae

1987 • 10 citations