Early steps of the hepatitis C virus life cycle

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

2005 • 2,741 citations

Complete Replication of Hepatitis C Virus in Cell Culture

2005 • 2,239 citations

Binding of Hepatitis C Virus to CD81

1998 • 2,042 citations

Robust hepatitis C virus infectionin vitro

2005 • 1,691 citations

Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry

2007 • 1,182 citations

The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus

2002 • 1,152 citations

Infectious Hepatitis C Virus Pseudo-particles Containing Functional E1–E2 Envelope Protein Complexes

2003 • 1,093 citations

Hepatitis C virus and other Flaviviridae viruses enter cells via low density lipoprotein receptor

1999 • 947 citations

Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles

2003 • 792 citations

Cell Entry of Hepatitis C Virus Requires a Set of Co-receptors That Include the CD81 Tetraspanin and the SR-B1 Scavenger Receptor

2003 • 607 citations

Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis

2006 • 563 citations

Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins

2007 • 515 citations

Claudins in occluding junctions of humans and flies

2006 • 511 citations

Cellular Binding of Hepatitis C Virus Envelope Glycoprotein E2 Requires Cell Surface Heparan Sulfate

2003 • 476 citations

Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses

2006 • 406 citations

Human Apolipoprotein E Is Required for Infectivity and Production of Hepatitis C Virus in Cell Culture

2007 • 405 citations

Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies

2007 • 370 citations

Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry

2006 • 370 citations

CD81 Is Required for Hepatitis C Virus Glycoprotein-Mediated Viral Infection

2004 • 354 citations

Hepatitis C Virus Entry Requires a Critical Postinternalization Step and Delivery to Early Endosomes via Clathrin-Coated Vesicles

2006 • 291 citations

An Interplay between Hypervariable Region 1 of the Hepatitis C Virus E2 Glycoprotein, the Scavenger Receptor BI, and High-Density Lipoprotein Promotes both Enhancement of Infection and Protection against Neutralizing Antibodies

2005 • 283 citations

The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus

2006 • 279 citations

Role of N-Linked Glycans in the Functions of Hepatitis C Virus Envelope Glycoproteins

2005 • 269 citations

Initiation of Hepatitis C Virus Infection Is Dependent on Cholesterol and Cooperativity between CD81 and Scavenger Receptor B Type I

2006 • 258 citations

Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1

2005 • 254 citations

Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81

2007 • 246 citations

High Density Lipoproteins Facilitate Hepatitis C Virus Entry through the Scavenger Receptor Class B Type I

2005 • 245 citations

Claudin-6 and Claudin-9 Function as Additional Coreceptors for Hepatitis C Virus

2007 • 216 citations

The Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope Protein

2007 • 208 citations

Cell surface expression of functional hepatitis C virus E1 and E2 glycoproteins

2003 • 195 citations

Hepatitis C virus entry: potential receptors and their biological functions

2006 • 188 citations

Characterization of Fusion Determinants Points to the Involvement of Three Discrete Regions of Both E1 and E2 Glycoproteins in the Membrane Fusion Process of Hepatitis C Virus

2007 • 175 citations

Hepatitis C Virus Particles and Lipoprotein Metabolism

2005 • 173 citations

Diverse CD81 Proteins Support Hepatitis C Virus Infection

2006 • 161 citations

Scavenger receptor BI: A scavenger receptor with a mission to transport high density lipoprotein lipids

2004 • 160 citations

Hepatitis C Virus Envelope Glycoprotein E2 Glycans Modulate Entry, CD81 Binding, and Neutralization

2007 • 159 citations

Scavenger Receptor BI and BII Expression Levels Modulate Hepatitis C Virus Infectivity

2007 • 154 citations

The interaction of natural hepatitis C virus with human scavenger receptor SR‐BI/Cla1 is mediated by ApoB‐containing lipoproteins

2006 • 150 citations

Serum-Derived Hepatitis C Virus Infection of Primary Human Hepatocytes Is Tetraspanin CD81 Dependent

2007 • 138 citations

Hepatitis C virus entry into host cells

2007 • 133 citations

Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells

2006 • 129 citations

Effect of Cell Polarization on Hepatitis C Virus Entry

2007 • 113 citations

The Exchangeable Apolipoprotein ApoC-I Promotes Membrane Fusion of Hepatitis C Virus

2007 • 92 citations

Serum amyloid A has antiviral activity against hepatitis C virus by inhibiting virus entry in a cell culture system

2006 • 90 citations

Assembly of a Functional HCV Glycoprotein Heterodimer

2007 • 89 citations

Different Domains of CD81 Mediate Distinct Stages of Hepatitis C Virus Pseudoparticle Entry

2006 • 89 citations

Transmembrane Domains of Hepatitis C Virus Envelope Glycoproteins: Residues Involved in E1E2 Heterodimerization and Involvement of These Domains in Virus Entry

2006 • 84 citations

Ceramide enrichment of the plasma membrane induces CD81 internalization and inhibits hepatitis C virus entry

2007 • 81 citations

Human Serum Amyloid A Protein Inhibits Hepatitis C Virus Entry into Cells

2007 • 73 citations

Deleted Work

1955 • 0 citations