Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line

1999 • 2,796 citations

Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to hepatitis C virus

1990 • 1,236 citations

Infectious Hepatitis C Virus Pseudo-particles Containing Functional E1–E2 Envelope Protein Complexes

2003 • 1,093 citations

Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles

2003 • 792 citations

Transmission of Hepatitis C by Intrahepatic Inoculation with Transcribed RNA

1997 • 718 citations

Replication of hepatitis C virus

2000 • 625 citations

Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon

2003 • 583 citations

Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee

1997 • 525 citations

Selectable Subgenomic and Genome-Length Dicistronic RNAs Derived from an Infectious Molecular Clone of the HCV-N Strain of Hepatitis C Virus Replicate Efficiently in Cultured Huh7 Cells

2002 • 387 citations

Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes

1993 • 363 citations

Association of hepatitis C virus in human sera with ?-lipoprotein

1992 • 358 citations

Persistent and Transient Replication of Full-Length Hepatitis C Virus Genomes in Cell Culture

2002 • 357 citations

Real-time detection system for quantification of hepatitis C virus genome

1999 • 279 citations

Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees

2002 • 269 citations

Hepatitis C virus particle detected by immunoelectron microscopic study

1994 • 255 citations

Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient*

2001 • 249 citations

Development of a Simple and Highly Sensitive Enzyme Immunoassay for Hepatitis C Virus Core Antigen

1999 • 216 citations

Hepatitis C virus: Detection of intracellular virus particles by electron microscop

1996 • 195 citations

Human Monoclonal Antibodies That Inhibit Binding of Hepatitis C Virus E2 Protein to CD81 and Recognize Conserved Conformational Epitopes

2000 • 188 citations

Previously Infected and Recovered Chimpanzees Exhibit Rapid Responses That Control Hepatitis C Virus Replication upon Rechallenge

2002 • 181 citations

Hepatitis C Virus: An Infectious Molecular Clone of a Second Major Genotype (2a) and Lack of Viability of Intertypic 1a and 2a Chimeras

1999 • 178 citations

Determining the Size of Non-A, Non-B Hepatitis Virus by Filtration

1987 • 172 citations

Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees

2000 • 153 citations

Nonhepatic Cell Lines HeLa and 293 Support Efficient Replication of the Hepatitis C Virus Genotype 2a Subgenomic Replicon

2004 • 130 citations

Genotype 2a Hepatitis C Virus Subgenomic Replicon Can Replicate in HepG2 and IMY-N9 Cells

2004 • 120 citations

The Clearance of Hepatitis C Virus Infection in Chimpanzees May Not Necessarily Correlate with the Appearance of Acquired Immunity

2002 • 93 citations

p26 protein and 33-nm particle associated with nucleocapsid of hepatitis C virus recovered from the circulation of infected hosts

1992 • 83 citations

Processing of hepatitis C virus core protein is regulated by its C‐terminal sequence

2003 • 33 citations