Immunological and structural similarities among allergens: Prerequisite for a specific and component‐based therapy of allergy

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

PROPHYLACTIC INOCULATION AGAINST HAY FEVER

1911 • 1,317 citations

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site.

1991 • 1,178 citations

Peptide and protein molecular weight determination by electrophoresis using a high-molarity tris buffer system without urea

1986 • 926 citations

The gene coding for the major birch pollen allergen Betv1, is highly homologous to a pea disease resistance response gene.

1989 • 674 citations

Identification of Profilin as a Novel Pollen Allergen; IgE Autoreactivity in Sensitized Individuals

1991 • 646 citations

Profilins constitute a novel family of functional plant pan-allergens.

1992 • 634 citations

Allergy to Apple, Carrot and Potato in Children with Birch Pollen Allergy

1983 • 434 citations

Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin)

1995 • 411 citations

Food Hypersensitivity in Patients with Pollen Allergy

1982 • 331 citations

Isolation and expression of an anther-specific gene from tomato

1989 • 287 citations

Cloning and Sequencing of Mal d 1, the Major Allergen from Apple (Malus domestica), and Its Immunological Relationship to Bet v 1, the Major Birch Pollen Allergen

1995 • 286 citations

Common epitopes of birch pollen and apples—Studies by western and northern blot

1991 • 284 citations

Identification of common allergenic structures in hazel pollen and hazelnuts: A possible explanation for sensitivity to hazelnuts in patients allergic to tree pollen

1992 • 277 citations

Molecular Characterization of Api g 1, the Major Allergen of Celery (Apium graveolens), and Its Immumological and Structural Relationships to a Group of 17‐kDa Tree Pollen Allergens

1995 • 237 citations

Four recombinant isoforms of Cor a I, the major allergen of hazel pollen, show different IgE‐binding properties

1993 • 215 citations

Characterization of a pollen-specific cDNA clone from Zea mays and its expression.

1989 • 190 citations

Skin testing with recombinant allergens rBet v 1 and birch profilin, rBet v 2: Diagnostic value for birch pollen and associated allergies

1996 • 188 citations

cDNA cloning and immunological characterization of the rye grass allergen Lol p I.

1990 • 174 citations

Isolation of cDNA encoding a newly identified major allergenic protein of rye-grass pollen: intracellular targeting to the amyloplast.

1991 • 168 citations

The profilin multigene family of maize: differential expression of three isoforms

1993 • 162 citations

Recombinant allergens for immunoblot diagnosis of tree-pollen allergy

1991 • 162 citations

Cloning of Amb a I (antigen E), the major allergen family of short ragweed pollen.

1991 • 160 citations

Purification and characterization of an allergen from celery immunochemically related to an allergen present in several other plant species. Identification as a profilin

1992 • 147 citations

cDNA cloning of a major allergen from timothy grass (Phleum pratense) pollen; characterization of the recombinant Phl pV allergen.

1993 • 144 citations

Properties of Tree and Grass Pollen Allergens: Reinvestigation of the Linkage between Solubility and Allergenicity

1993 • 143 citations

Diagnosis of Grass Pollen Allergy with Recombinant Timothy Grass <i>(Phleum pratense)</i> Pollen Allergens

1992 • 139 citations

Recombinant allergens for diagnosis and therapy of allergic diseases

1995 • 131 citations

Cross-Reactivity of IgE Antibodies with Allergens in Birch Pollen, Fruits and Vegetables

1984 • 130 citations

Basic and practical aspects of recombinant allergens

1995 • 130 citations

Identification of profilin as an IgE‐binding component in latex from Hevea brasiliensis: clinical implications

1995 • 127 citations

Cloning and Sequencing of cDNA Coding for Cry j I, a Major Allergen of Japanese Cedar Pollen

1994 • 126 citations

Complementary DNA cloning of the major allergenPhl p I from timothy grass (Phleum pratense); recombinantPhl p I inhibits IgE binding to group I allergens from eight different grass species

1994 • 119 citations

PCR based cloning and sequencing of isogenes encoding the tree pollen major allergen Car b I from Carpinus betulus, hornbeam

1992 • 110 citations

Molecular characterization of dog albumin as a cross-reactive allergen

1994 • 106 citations

Nucleotide sequence analysis of three cDNAs coding for Poa p IX isoallergens of Kentucky bluegrass pollen.

1991 • 105 citations

XI, a new major grass pollen allergen, is a member of a family of soybean trypsin inhibitor-related proteins

1995 • 100 citations

Molecular cloning and characterization of profilin from tobacco (Nicotiana tabacum): increased profilin expression during pollen maturation

1995 • 95 citations

Allergen nomenclature

1995 • 95 citations

Construction of a Combinatorial IgE Library from an Allergic Patient

1996 • 94 citations

Complementary DNA cloning and expression in Escherichia coli of Aln g I, the major allergen in pollen of alder (Alnus glutinosa)

1992 • 93 citations

Molecular characterization of Phl p II, a major timothy grass (Phleum pratense) pollen allergen

1993 • 86 citations

Isolation of an immunodominant IgE hapten from an epitope expression cDNA library. Dissection of the allergic effector reaction.

1994 • 84 citations

T-cell epitopes of Phl p 1, major pollen allergen of timothy grass (Phleum pratense): Evidence for crossreacting and non-crossreacting T-cell epitopes within grass group I allergens

1995 • 84 citations

Immunological Investigation of Possible Structural Similarities between Pollen Antigens and Antigens in Apple, Carrot and Celery Tuber

1985 • 78 citations

cDNA Cloning and Expression of Cry jII, the Second Major Allergen of Japanese Cedar Pollen

1994 • 78 citations

cDNA Cloning and Expression of Timothy Grass (Phleum pratense) Pollen Profilin in Escherichia coli: Comparison with Birch Pollen Profilin

1994 • 76 citations

Hypersensitivity to Foods among Birch Pollen‐Allergic Patients

1983 • 67 citations

Characterization of Phl p 4, a major timothy grass

1996 • 67 citations

IgE-binding capacity of recombinant timothy grass (Phleum pratense) pollen allergens

1994 • 64 citations

Purification, Characterization, and cDNA Cloning of Profilin from Phaseolus vulgaris

1995 • 54 citations

Tracking Down Plant Genes: Paths, Patterns, and Footprints

1989 • 46 citations

Isolation and characterization of an olive allergen‐like protein from lilac pollen

1994 • 45 citations

Induction of IgE antibodies with predefined specificity in rhesus monkeys with recombinant birch pollen allergens, Bet v 1 and Bet v 2

1996 • 42 citations

Polymerase Chain Reaction Based cDNA Cloning of Wheat Profilin: A Potential Plant Allergen

1994 • 40 citations

Common IgE-epitopes of recombinant Phl p I, the major timothy grass pollen allergen and natural group I grass pollen isoallergens

1996 • 40 citations

Cloning, expression, and immunological characterization of recombinant Lolium perenne allergen Lol p II.

1993 • 37 citations

Expression of Zm13, a pollen specific maize protein, in Escherichia coli reveals IgE‐binding capacity and allergenic potential

1996 • 15 citations