Idiopathic Pulmonary Fibrosis: Cellular and Molecular Pathogenesis

Natural History and Treated Course of Usual and Desquamative Interstitial Pneumonia

1978 • 802 citations

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF

1985 • 719 citations

Idiopathic Pulmonary Fibrosis

1976 • 706 citations

Cell number and cell characteristics of the normal human lung.

1982 • 705 citations

Interstitial Lung Diseases of Unknown Cause

1984 • 696 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

The platelet-derived growth factor

1978 • 649 citations

Unilateral Lung Transplantation for Pulmonary Fibrosis

1986 • 617 citations

Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme.

1984 • 612 citations

Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis.

1977 • 570 citations

Interstitial lung disease: Current concepts of pathogenesis, staging and therapy

1981 • 549 citations

Cryptogenic fibrosing alveolitis: clinical features and their influence on survival

1980 • 529 citations

The nature and action of granulocyte-macrophage colony stimulating factors

1980 • 526 citations

An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis

1978 • 472 citations

Desquamative interstitial pneumonia

1965 • 468 citations

Acute diffuse interstitial fibrosis of the lungs

1944 • 424 citations

Exaggerated Spontaneous Release of Platelet-Derived Growth Factor by Alveolar Macrophages from Patients with Idiopathic Pulmonary Fibrosis

1987 • 420 citations

Permissive effect of the extracellular matrix on cell proliferation in vitro.

1980 • 412 citations

Characterization of fibronectin interactions with glycosaminoglycans and identification of active proteolytic fragments.

1980 • 410 citations

Collagen in health and disease

1982 • 355 citations

Colchicine in the Treatment of Cirrhosis of the Liver

1988 • 327 citations

A novel serine esterase expressed by cytotoxic T lymphocytes

1985 • 319 citations

Diffuse fibrosing alveolitis (diffuse interstitial fibrosis of the lungs): Correlation of histology at biopsy with prognosis

1967 • 317 citations

Bronchoalveolar Lavage in Interstitial Lung Disease

1978 • 302 citations

Human Alveolar Macrophage Growth Factor for Fibroblasts

1982 • 301 citations

Role of fibronectin as a growth factor for fibroblasts.

1983 • 298 citations

Circulating Immune Complexes in the Idiopathic Interstitial Pneumonias

1978 • 281 citations

Human alveolar macrophages produce leukotriene B4.

1982 • 278 citations

Ganglioside inhibition of fibronectin-mediated cell adhesion to collagen.

1979 • 259 citations

Bronchoalveolar lavage in pulmonary fibrosis: comparison of cells obtained with lung biopsy and clinical features

1980 • 254 citations

Human Alveolar Macrophage-derived Chemotactic Factor for Neutrophils

1980 • 253 citations

The prognosis of cryptogenic fibrosing alveolitis

1972 • 253 citations

Idiopathic pulmonary fibrosis. Pretreatment bronchoalveolar lavage cellular constituents and their relationships with lung histopathology and clinical response to therapy.

1987 • 253 citations

Bronchoalveolar lavage fluid cell counts in cryptogenic fibrosing alveolitis and their relation to therapy.

1980 • 250 citations

Morphologic-physiologic correlates of the severity of fibrosis and degree of cellularity in idiopathic pulmonary fibrosis.

1979 • 237 citations

Mechanisms of neutrophil accumulation in the lungs of patients with idiopathic pulmonary fibrosis.

1981 • 235 citations

Alveolar macrophage-derived chemotactic factor: kinetics of in vitro production and partial characterization.

1980 • 233 citations

Heterogeneous Proliferative Characteristics of Human Adult Lung Fibroblast Lines and Clonally Derived Fibroblasts from Control and Fibrotic Tissue

1988 • 228 citations

Tolerance and contact sensitivity to DNFB in mice. I. In vivo detection by ear swelling and correlation with in vitro cell stimulation.

1974 • 220 citations

Collagen polymorphism in the lungAn immunochemical study of pulmonary fibrosis

1980 • 220 citations

Definition and Classification of Interstitial Pneumonias in Human Pathology1

2015 • 218 citations

Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders.

1983 • 217 citations

Collagenase in the Lower Respiratory Tract of Patients with Idiopathic Pulmonary Fibrosis

1979 • 205 citations

Structure of alveolar epithelial cells in patients with fibrotic lung disorders.

1982 • 199 citations

Lung injury induced by leukocytic proteases.

1979 • 183 citations

Platelet-derived growth factor. Structure, function, and roles in normal and transformed cells.

1984 • 178 citations

Lung Collagen Composition and Synthesis

1974 • 178 citations

Frontiers of Pulmonary Radiology.

1970 • 177 citations

Heterogeneity of Normal Human Diploid Fibroblasts: Isolation and Characterization of One Phenotype

1984 • 175 citations

Small Airways in Idiopathic Pulmonary Fibrosis

1977 • 175 citations

The connective tissue of lung.

1975 • 173 citations

The value of serial bronchoalveolar lavages in assessing the clinical progress of patients with cryptogenic fibrosing alveolitis.

1987 • 167 citations

An Inhibitor of Cell Proliferation Released by Cultures of Macrophages

1974 • 151 citations

Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages.

1986 • 144 citations

Tolerance and Contact Sensitivity to Dnfb in Mice

1974 • 134 citations

Localization of the cell attachment region in types I and II collagens

1976 • 131 citations

Auto-antibody Studies in Interstitial Pulmonary Fibrosis

1965 • 130 citations

THE CAUSE OF ARTERIAL HYPOXEMIA AT REST IN PATIENTS WITH “ALVEOLAR-CAPILLARY BLOCK SYNDROME”*

1962 • 126 citations

Lung collagen: more than scaffolding.

1986 • 122 citations

Lavage type III procollagen N-terminal peptides in human pulmonary fibrosis and sarcoidosis.

1983 • 111 citations

Human alveolar macrophage inhibition of lung fibroblast growth. A prostaglandin-dependent process.

1985 • 110 citations

The diffusing capacity of the pulmonary membrane and the pulmonary capillary blood volume in cardiopulmonary disease.

1958 • 93 citations

Idiopathic Pulmonary Fibrosis: Abnormalities in Bronchoalveolar Lavage Fluid Phospholipids

1988 • 91 citations

Lung Connective Tissue

1983 • 90 citations

Recombinant gamma, alpha, and beta interferon regulation of human lung fibroblast proliferation.

1987 • 90 citations

Desquamative Interstitial Pneumonitis

1977 • 87 citations

Colchicine Suppresses the Release of Fibroblast Growth Factors from Alveolar MacrophagesIn Vitro: The Basis of a Possible Therapeutic Approach to the Fibrotic Disorders

1988 • 84 citations

The regulation of ventilation in diffuse pulmonary fibrosis

1965 • 83 citations

Fibronectin and Procollagen 3 Levels in Bronchoalveolar Lavage of Asbestos-Exposed Human Subjects and Sheep

1986 • 78 citations

Collagen in the human lung. Quantitation of rates of synthesis and partial characterization of composition.

1975 • 78 citations

Connective tissue of the normal and fibrotic human liver

1983 • 77 citations

Regulation of the release of alveolar macrophage-derived neutrophil chemotactic factor.

1980 • 77 citations

Clonal heterogeneity in the fibroblast response to mononuclear cell derived mediators

1984 • 76 citations

Serum type III procollagen peptide concentration in cryptogenic fibrosing alveolitis and its clinical relevance.

1984 • 76 citations

Distribution of Ventilation-Perfusion Ratios in Patients with Interstitial Lung Disease

1976 • 76 citations

Cells, collagen and idiopathic pulmonary fibrosis

1978 • 74 citations

Pharmacologic Suppression of the Neutrophil Component of the Alveolitis in Idiopathic Pulmonary Fibrosis

1987 • 73 citations

Effect of Intermittent High Dose Parenteral Corticosteroids on the Alveolitis of Idiopathic Pulmonary Fibrosis^1,2

1983 • 73 citations

Lung collagen heterogeneity. Synthesis of type I and type III collagen by rabbit and human lung cells in culture.

1976 • 72 citations

Platelet-derived growth factor agonist activity of a secreted form of the v-sis oncogene product.

1985 • 72 citations

Diffuse pulmonary alveolar fibrosis

1974 • 71 citations

Correlation of Changes in Pulmonary Surfactant Phospholipids with Compliance in Bleomycin-Induced Pulmonary Fibrosis in the Rat

1987 • 68 citations

Quantitation of Types I and III Collagen in Biopsy Lung Samples from Patients with Cryptogenic Fibrosing Alveolitis

1984 • 68 citations

Human monocyte stimulation of fibroblast growth by a soluble mediator(s).

1980 • 64 citations

Increased Procollagen III Aminoterminal Peptide-related Antigens and Fibroblast Growth Signals in the Lungs of Patients with Idiopathic Pulmonary Fibrosis

1988 • 62 citations

Molecular pathology of connective tissues

1973 • 60 citations

Interstitial Pulmonary Fibrosis—Which Cell is the Culprit?^1,2

1983 • 59 citations

The structure of collagen fibrils

1974 • 59 citations

Pulmonary mechanics in diffuse fibrosing alveolitis.

1975 • 58 citations

Increased Bronchoalveolar IgG-Secreting Cells in Interstitial Lung Diseases

1980 • 57 citations

Chapter 3 The Fibroblast of Human Lung Alveolar Structures: A Differentiated Cell with a Major Role in Lung Structure and Function

1980 • 55 citations

Lung Collagen Heterogeneity

1974 • 54 citations

Characterization of fractionated human diploid fibroblast cell populations

1976 • 54 citations

Pathophysiology of Interstitial Pulmonary Fibrosis

1962 • 51 citations

Studies on respiratory mechanics and the work of breathing in pulmonary fibrosis

1959 • 48 citations

Usual and Desquamative Interstitial Pneumonia

1976 • 37 citations

Modulation of the effects of alveolar macrophages on lung fibroblast collagen production rate.

1987 • 31 citations

Isolation of type III collagen from human adult parenchymal lung tissue

1977 • 31 citations

The Identification of Collagen Messenger RNA

1974 • 29 citations

Pulmonary Interstitial Fibrosis Induced in Hapten-Immune Hamsters

1987 • 24 citations

Comparison of the Alveolitis of Sarcoidosis and Idiopathic Pulmonary Fibrosis

1979 • 24 citations

Hydrolysis: Peptide Bonds

1971 • 22 citations

Phenotypic variability among density-fractionated human lung fibroblasts.

1987 • 21 citations

The concept of the Hamman-Rich syndrome. A critique.

1962 • 19 citations

Antinuclear antibody and lymphocyte responses to nuclear antigens in patients with lung disease

1975 • 19 citations

[Idiopathic diffuse interstitial lung disease].

2000 • 18 citations

Pulmonary Function in Infiltrative Lung Disease

1973 • 17 citations

Morphometric and Angiographic Studies in Diffuse Interstitial Pulmonary Fibrosis

2015 • 16 citations

Diffuse Interstitial Pulmonary Fibrosis

1967 • 16 citations

Bronchoalveolar Lavage Fluid Neutrophils Increase after Corticosteroid Therapy in Smokers with Idiopathic Pulmonary Fibrosis^1–4

1986 • 15 citations

Separation and Characterization of Lymphocytes from Rat Lung Parenchyma

1984 • 10 citations

SOME OBSERVATIONS ON THE HAMMAN-RICH DESEASE

1961 • 10 citations

Alveolar macrophage lysosomal enzyme and C3b receptors in cryptogenic fibrosing alveolitis.

1980 • 10 citations

The Platelet-Derived Growth Factor

1980 • 9 citations

In vitro suppression of fibroblast growth inhibitory lymphokine production by asbestos.

1983 • 6 citations

Diagnostic techniques in diffuse or miliary lung diseases: experience with 381 patients.

1966 • 6 citations

DIFFUSE INTERSTITIAL PULMONARY FIBROSIS

1964 • 6 citations

Comparison of the Alveolitis of Sarcoidosis and Idiopathic Pulmonary Fibrosis

1979 • 4 citations

Hamman-Rich syndrome. Idiopathic pulmonary interstitial fibrosis of the lung.

1969 • 3 citations